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Volume 16 (11); 2025

Research Papers

Diallyl Trisulfide Enhances Doxorubicin Chemosensitivity by Inhibiting the Warburg Effect and Inducing Apoptosis in Breast Cancer Cells
Chun-Ming Chang, Wei-Jan Wang, Thomas G. Mhone, Wen-Kun Ho, Chih-Jung Chen, Shawn Shang-Chuan Ng, Chi-Cheng Li, Chia-Hua Kuo, Chih-Yang Huang, Wei-Wen Kuo
J. Cancer 2025; 16(11): 3283-3295. doi:10.7150/jca.113578
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Investigating the Role of Lactate-Related Genes in Radiotherapy Resistance of Lung Cancer by Integrated Bioinformatics and Experiment Validation
Qianqian Li, Lili Shen, Yanguang Yang, Guomei Tai, Qiwei Zhu, Canyu Liu, Qin Ge, Qiong Yi
J. Cancer 2025; 16(11): 3296-3313. doi:10.7150/jca.113046
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Integrating Bulk RNA and Single-cell transcriptome to explore the role of glycan-related genes in lung adenocarcinoma
Keyun Zhu, Changqing Yang, Guixin Wang, XingKai Wang, Chengbin Lin, Yingxi Li, Ningning He, Yao Tian, Weiyu Shen
J. Cancer 2025; 16(11): 3314-3328. doi:10.7150/jca.115989
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Paxillin promotes the invasion and migration of polyploid giant cancer cells with daughter cells after arsenic trioxide treatment by regulating the expression of cathepsin B/D
Jiangping Wang, Xiaorui Wang, Na Li, Kai Liu, Shiwu Zhang
J. Cancer 2025; 16(11): 3329-3342. doi:10.7150/jca.115892
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The Prediction Model for Triple-Negative Breast Cancer Prognosis and Immunotherapy Efficacy Based on Single-Cell Sequencing of CD8+ T cells
Jiarong Yi, Yejun Qiao, Zhengchong Xiong, Jikun Feng, Xiazi Zouxu, Shuang Zeyu, Xi Wang
J. Cancer 2025; 16(11): 3343-3354. doi:10.7150/jca.115507
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Implication of CDKN2A in cuproptosis through defining cuproptosis-related gene signature in ovarian cancer
Beilei Zhang, Zhaojie Yang, Yinuo Zheng, Yongchao He, Yulu Yan, Jiarui Song, Fu Wang, Ruifang An
J. Cancer 2025; 16(11): 3355-3371. doi:10.7150/jca.115374
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Pan-cancer analysis reveals SGO1 as a potential cancer prognostic and immunological biomarker
Yongqiang Wang, Xianming Long, Long Zhang, Fangfang Zhou, Miaochun Zhong
J. Cancer 2025; 16(11): 3372-3388. doi:10.7150/jca.115334
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Integrative Analysis of Histone Deacetylases Reveals the Potential Role and Prognostic Value of HDAC7 in Hepatocellular Carcinoma
Changjiang Yang, Zhenze Yu, Ranran Wang, Meijing Zhang, Zihan Zhao
J. Cancer 2025; 16(11): 3389-3402. doi:10.7150/jca.112983
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DUSP9 is Up-Regulated and Promotes Tumor Progression in Head and Neck Squamous Cell Carcinoma
Yuzhe Hu, Yue Li, Chenfeng Jiang, Wenling Han, Xiaohong Chen, Pingzhang Wang, Hongbo Xu
J. Cancer 2025; 16(11): 3403-3414. doi:10.7150/jca.110597
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HLA-DOB: A Key “Coordinator” Between Cutaneous Melanoma and Psoriasis
Yingxi Li, Jing Luo, Dongchen Tian, Chenxi Li, Chen Wu, Guixin Wang, Ruitan Guo, Long He, Lin Li, Yao Tian, Lizhi Hu
J. Cancer 2025; 16(11): 3415-3424. doi:10.7150/jca.110306
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A Promising Prognostic Signature Consisting of Fatty Acid Metabolism Genes based on Machine Learning Predicts Biochemical Recurrence and Aids ARSI Therapy in Prostate Cancer
Zhenjie Wu, Yulin Deng, Yuanfa Feng, Zeheng Tan, Shanghua Cai, Huichan He, Wenjun Yin, Jinchuang Li, Weicheng Tian, Jianming Lu, Wenjie Xie, Jundong Lin, Jianheng Ye, Zhaodong Han, Weide Zhong
J. Cancer 2025; 16(11): 3450-3463. doi:10.7150/jca.112597
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Risk of Bladder Cancer in Patients with Chronic Indwelling Catheters: A Real-World Data Analysis
Wen-Hsin Tseng, Chang-Hua Lee, Ren-Jie Lin, Chung-Han Ho, Chien-Liang Liu, Steven K. Huang, Allen W. Chiu, Chien-Feng Li, Yow-Ling Shiue
J. Cancer 2025; 16(11): 3464-3472. doi:10.7150/jca.114223
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A nomogram based on plasma HSP90α and NLR for predicting prognosis in advanced gastric cancer patients treated with PD-1 inhibitors
Ziting Qu, Yan Zhang, Lili Lu, Xiaowen Qi, Tengteng Zhang, Zhiyan Zhao, Yiyin Zhang, Kangsheng Gu
J. Cancer 2025; 16(11): 3473-3484. doi:10.7150/jca.114975
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Exploration of the relationship between apoptosis related characteristic genes and the prognosis of HCC
Qiyao Zhang, Zhen Cao, Hongtao Cao, Hao Wu, Shangcheng Yan, Yuqian Kan, Xinwei Cui, Yingchun Feng, Ziwen Liu
J. Cancer 2025; 16(11): 3485-3496. doi:10.7150/jca.114359
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Combined Bioinformatics Analyses and Immunohistochemical Validation Reveal the Prognostic Relevance and Immune-Related Role of CIITA in Breast Cancer
Wenge Li, Xin Yu, Yue Xia, Juanjuan Li
J. Cancer 2025; 16(11): 3513-3524. doi:10.7150/jca.118933
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Integrating Single-Cell and Bulk RNA Sequencing Reveals the Malignant Phenotype of CBX4 in Prostate Cancer
Zihao Liu, Yang Liu, Zhinan Fu, Hua Huang, Runpeng Wang, Zhun Wang, Shuanghe Peng, Jiahao Wang, Ziqi Fang, Liwei Liu, Ruibing Chen, Yong Wang
J. Cancer 2025; 16(11): 3525-3536. doi:10.7150/jca.115613
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Integrative Multi-Omics Analysis Reveals Key Metabolic Regulators and Prognostic Biomarkers in Pediatric and Adult Thyroid Cancer
Bin Ling, Mengran Tian, Jinmiao Wang, Wei Luo, Jialong Yu, Xing Wan, Qiman Dong, Ming Gao, Min Zhao, Xiangqian Zheng, Xianhui Ruan
J. Cancer 2025; 16(11): 3551-3566. doi:10.7150/jca.117034
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Reviews

Strategies to Overcome PD-1/PD-L1 Blockade Resistance: Focusing on Combination with Immune Checkpoint Blockades
Dinglin Liu, Haoyue Xiao, Ying Xiang, Dian Zhong, Yuchen Liu, Yunfei Wang, Weijia Zhang
J. Cancer 2025; 16(11): 3425-3449. doi:10.7150/jca.108163
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Latest Advancements of Natural Products in Combating Ovarian Cancer
Yangyuxiao Lu, Hong Huang, Yuling Chen, Keren He, Mengqi Fang, Ye Xu, Yuan Zhou, Fangfang Tao
J. Cancer 2025; 16(11): 3497-3512. doi:10.7150/jca.118209
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H3K14: A histone site closely related to diseases
Chenyu Fan, Feng Zeng, Yan Lei, Qian He, Kun Liu, Juan Xu, Yanhong Zhou
J. Cancer 2025; 16(11): 3537-3550. doi:10.7150/jca.118273
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