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Volume 17 (1); 2026

Research Papers

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Loss of CDKN2A/B is a Hallmark of RTK II Glioblastomas
Celina K. Langwieder, Dorothee Hölzl, Georg Hutarew, Hans U. Schlicker, Beate Alinger-Scharinger, Christoph Schwartz, Karl Sotlar, Theo F. J. Kraus
J. Cancer 2026; 17(1): 1-9. doi:10.7150/jca.122609
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The Role of Inflammatory Biomarkers in PIPAC: Predicting Survival and Treatment Completion in Patients with Peritoneal Metastasis
Signe Roensholdt, Martin Graversen, Sönke Detlefsen, Claus Fristrup, Per Pfeiffer, Michael Bau Mortensen
J. Cancer 2026; 17(1): 10-20. doi:10.7150/jca.123687
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Identification of key ferroptosis-related targets in colorectal cancer: A transcriptomics-driven study via machine learning and AUcell analysis of single-cell RNA-sequencing
Zhiqiang Liang, Zehui Hou, Zhuomin Yu, Bing Zeng, Fang Li, Jingjing Wu, Yingru Li, Zhipeng Jiang
J. Cancer 2026; 17(1): 32-48. doi:10.7150/jca.114522
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Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization
Mahmoud Mansour, Sabrina van Ginkel, Maaz Alata, Ibrahim Bani, Isra Elhussin
J. Cancer 2026; 17(1): 49-58. doi:10.7150/jca.124252
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Interleukin-17 receptor A drives cancer stem-like properties in colorectal cancer through STAT3 activation
Jeng-Kai Jiang, Chi-Hung Lin, Chun-Chi Lin, Liang-Chuan Lo, Po-Yen Sung, Zhen-Yu Wen, Chien-Ping Lin, Ting-An Chang, Chih-Yung Yang
J. Cancer 2026; 17(1): 74-85. doi:10.7150/jca.121654
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Ganoderma microsporum Immunomodulatory Protein (GMI) Enhances Phagocytosis by Suppressing STAT3/CD47 Signaling in EGFR-Mutant NSCLC Resistant to Gefitinib and Osimertinib
Ya-Chu Hsieh, I-Lun Hsin, Ling-Yen Chiu, Yu-Chien Hung, Yu-Ting Kang, Hui-Yi Chang, Ching-Hsiung Lin, Jiunn-Liang Ko, Yu-Fan Liu
J. Cancer 2026; 17(1): 86-98. doi:10.7150/jca.124363
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CES3 promotes NSCLC progression via lipid metabolic reprogramming regulated by TFAP2A
Pengfei Luo, Zirui Huang, Sijuan Ding, Zhangwen Tang, Yanhong Wei, Shaohui Jiang, Ruoting Tang, Fang Li, Han Yang, Lujun Zhao
J. Cancer 2026; 17(1): 99-108. doi:10.7150/jca.118395
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Association of Ion Concentration with Immune-Related Adverse Events and Prognosis in Lung Cancer Patients Treated with PD-1/PD-L1 Inhibitors
Chen-Wei Liao, Juan Chen, Jia-Si Liu, Lei She, Ting Zou, Ya Wang, Zhan Wang, Zhao-Qian Liu
J. Cancer 2026; 17(1): 109-116. doi:10.7150/jca.120666
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Disulfiram/Copper Combination as a Potential Therapeutic Approach for Hepatocellular Carcinoma: Targeting the ATF3-Mitochondrial Cell Death Pathway
Jing Cao, Jing Deng, Xinhua Li, Yaqiong Chen, Jialei Wang, Yutian Chong, Jiao Gong, Bingliang Lin
J. Cancer 2026; 17(1): 117-130. doi:10.7150/jca.113442
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Sulforaphane-cysteine elicits apoptosis through JNK-mediated caspase activation in oral squamous cell carcinoma cells
Yen-Lin Chen, Yi-Tzu Chen, Wei-En Yang, Chun-Wen Su, Meng-Ying Tsai, Shih-Chi Su, Shun-Fa Yang, Chiao-Wen Lin
J. Cancer 2026; 17(1): 131-141. doi:10.7150/jca.126381
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Comprehensive characterization of AP-1 adaptor complex genes in lung cancer reveals AP1AR as a novel prognostic and therapeutic biomarker
Dahlak Daniel Solomon, I-Jeng Yeh, Hsin-Liang Liu, Che-Yu Su, Yung-Kuo Lee, Ching-Chung Ko, Hui-Ru Lin, Sachin Kumar, Do Thi Minh Xuan, Neethu Palekkode, Ayman Fathima, Hung-Yun Lin, Chih-Yang Wang, Meng-Chi Yen
J. Cancer 2026; 17(1): 142-156. doi:10.7150/jca.125763
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Multi-Omics and Single-Cell Dissection of Exostosin Glycosyltransferases (EXT1/EXT2) Reveals Divergent Oncogenic Roles and Therapeutic Vulnerabilities in Gliomas
Yi-Chun Chiang, Chih-Yang Wang, Neethu Palekkode, Shun-Fa Yang, Kai-Fu Chang, Ching-Chung Ko, Chih-Hsuan Chang, Hui-Ru Lin, Chi-Jen Wu, Yu-Cheng Ho, Chih-Chun Lin, Chien-Han Yuan, Sachin Kumar, Dahlak Daniel Solomon, Juan Lorell Ngadio, Fitria Sari Wulandari, Do Thi Minh Xuan, Chung-Bao Hsieh, Meng-Chi Yen, I-Jeng Yeh, Pi-Chan Ko, Chia-Lung Shih, Hoi-Bor Chan, Yung-Kuo Lee, Ngoc Uyen Nhi Nguyen
J. Cancer 2026; 17(1): 177-196. doi:10.7150/jca.123965
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Reviews

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Biomarkers for Recurrence and Prognosis in Metastatic Urothelial Cancer: Emerging Clinical Applications
Alicia Sánchez Cendra, Linda Rocio Ospino, Leonel Pekarek, Yumna Dbouk, Sami Chnaiker, Ana Luengo, Tania Villamor, Amalia Corralo, Raul Diaz-Pedrero, Laura Lopez-Gonzalez, Miguel A Saez, Majd N Michael Alhaddadin, María Belén Alonso-Bartolome, Carlos Casanova-Martín, Melchor Alvarez-Mon, Leonor Garcia Rodriguez, Silvestra Barrena-Blázquez, Miguel A Ortega
J. Cancer 2026; 17(1): 21-31. doi:10.7150/jca.123907
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Cancer Cell Dormancy and Chemotherapy Resistance
Jingxian Hu, Wei Zhou, Ying Zhao, Peiran Li, Zhenying Zhao, Wei Wang, Wenhong Wang, Yijia Wang
J. Cancer 2026; 17(1): 59-73. doi:10.7150/jca.123742
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Macrophages in Colorectal Cancer: from Normal Mucosa to Distant Metastasis: Beyond the M1/M2 Paradigm
Sergii Pavlov, Esraa Ali, Filip Ambrozkiewicz, Wenjing Ye, Marie Rajtmajerová, Václav Liška, Kari Hemminki, Andriy Trailin
J. Cancer 2026; 17(1): 157-176. doi:10.7150/jca.126772
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