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Volume 16 (15); 2025

Research Papers

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Capsaicin, the Pungent Component of Red Chili Pepper, induces p21-mediated Cell Cycle Arrest in Renal Cell Carcinoma via Downregulating GLI1: an Experimental Research In Vitro
Long Zheng, Yongchao He, Hao Huang, Wei Qu
J. Cancer 2025; 16(15): 4284-4291. doi:10.7150/jca.119706
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The Prognostic Value of Lymph Node Downstaging Following Neoadjuvant Chemoimmunotherapy for Non-Small Cell Lung Cancer
Marissa Guo, Mahmoud Abdel-Rasoul, Jeremy Chang, Aaron Guo, Ioana Baiu, Desmond M. D'Souza, Robert E. Merritt, Peter J. Kneuertz
J. Cancer 2025; 16(15): 4292-4301. doi:10.7150/jca.119881
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Chemopreventive Targeting of Oncogenic Stemness: EGCG-Mediated Suppression of the HIF-1α-PPARγ-Cancer Stem Cells Transcriptional Signature in 3D Glioblastoma Spheroids
Abdallah Fallah, Maellis Payet-Desruisseaux, Alain Zgheib, Bogdan Alexandru Danalache, Nicoletta Eliopoulos, Borhane Annabi
J. Cancer 2025; 16(15): 4302-4315. doi:10.7150/jca.124247
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Genetic association of NEAT1 gene polymorphism with the progression of colorectal cancer
Bei-Hao Shiu, Yi-Hsien Hsieh, Chi-Chou Huang, Chih-Hsin Tang, Lun-Ching Chang, Shih-Chi Su, Shun-Fa Yang
J. Cancer 2025; 16(15): 4338-4345. doi:10.7150/jca.123558
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Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer
Haonan Dong, Hongqiong Li, Shi Chen, Qun Wang, Yawei Zhang, Hongjin Shi, Jieming Zuo, Junhao Chen, Jiansong Wang, Haifeng Wang
J. Cancer 2025; 16(15): 4357-4370. doi:10.7150/jca.119178
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Validation of WHO 2017 Classification and Identification of Prognostic Factors in Patients with Pancreatic Neuroendocrine Neoplasms: A Real-World Experience in Taiwan
Wei-Pang Ho, Wen-Chi Chou, Chia-Hsun Hsieh, Ming-Mo Hou, Wen-chi Shen, Pei-Wei Huang, Chiao-En Wu, Chih-Chung Hsu, Wen-Cheng Chang, Yung-Chia Kuo, Hung-Chih Hsu, Ching-Fu Chang, Po-Jung Su, Ren-Chin Wu, Jen-Shi Chen, Wen-Kuan Huang
J. Cancer 2025; 16(15): 4371-4377. doi:10.7150/jca.123900
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FoxM1 promotes TFAM expression and regulates Mitochondrial Dynamics in Glioblastoma cells
Nida Fatima Moazzam, Muhammad Asad Iqbal, Xiu Han, Zhangzuo Li, Aihua Gong
J. Cancer 2025; 16(15): 4378-4389. doi:10.7150/jca.111013
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The immunosuppressive role of CCR8+ Tregs in gastric cancer
Koichi Jinushi, Yoshinori Hayashi, Koichi Morishita, Takuro Saito, Atsunari Kawashima, Yuichiro Doki, Azumi Ueyama, Hisashi Wada
J. Cancer 2025; 16(15): 4390-4399. doi:10.7150/jca.121363
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2023 FIGO Staging of Endometrial Cancer with Molecular Classification: Dawn and Challenges
Wei Zhao, Qiqi Xu, Peiyu Feng, Dongxiao Hu, Hongyan Xu, Xiaofei Zhang, Wanrun Lin, Feng Zhou, Yang Li
J. Cancer 2025; 16(15): 4400-4407. doi:10.7150/jca.120459
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Dasatinib inhibits PD-L1 expression via a proteasomal pathway in pancreatic ductal adenocarcinoma cells
Ching-Chung Ko, Hui-Ying Li, Pei-Ming Yang
J. Cancer 2025; 16(15): 4408-4414. doi:10.7150/jca.124262
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Isoginkgetin Induces Caspase Cascade Activation and Cell Apoptosis via JNK Signaling in Oral Cancer
Wei-En Yang, Chun-Yi Chuang, Chiao-Wen Lin, Chun-Wen Su, Meng-Ying Tsai, Shih-Chi Su, Heng-Hsiung Wu, Shun-Fa Yang, Yi-Tzu Chen
J. Cancer 2025; 16(15): 4415-4425. doi:10.7150/jca.123992
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COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling
Xing Ji, Yongyang Yun, Zhenpeng Zhu, Tianyu Wu, Mingjian Ruan, Yu Fan, Qian Zhang
J. Cancer 2025; 16(15): 4426-4439. doi:10.7150/jca.120607
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Reviews

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Molecular Mechanisms and Novel Therapeutics Targeting Ferroptosis in Gastric Cancer: A Literature Review
Hsi-Lung Hsieh, Ming-Chin Yu, Hui-Ching Tseng, Yi-Hsuan Wu, Ming-Ming Tsai
J. Cancer 2025; 16(15): 4270-4283. doi:10.7150/jca.119757
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Divulging Patterns: An Analytical Review for Machine Learning Methodologies for Breast Cancer Detection
Alveena Saleem, Muhammad Umair, Muhammad Tahir Naseem, Muhammad Zubair, Silvia Aparicio Obregon, Ruben Calderon Iglesias, Shoaib Hassan, Imran Ashraf
J. Cancer 2025; 16(15): 4316-4337. doi:10.7150/jca.118698
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Emerging Roles of PTTG1/Securin in Breast Cancer
Lingyuan Min, Shaojie Feng, Xiuxiu Liu, Yan Zhang, Mengmeng Zhao, Huan Shi, Xianqiang Liu, Tianning Wang
J. Cancer 2025; 16(15): 4346-4356. doi:10.7150/jca.121650
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