Journal of Cancer
ISSN: 1837-9664
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ISSN: 1837-9664
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Volume 16 (14); 2025
Research Papers
Tyrosine Kinase Inhibitors Outperform Immune Checkpoint Inhibitors in Bone-Predominant Metastatic Renal Cell Carcinoma: A Multicenter Real-World Analysis
Lingbin Meng, Sarah P. Psutka, Jinesh Gheeya, Mingjia Li, Meghana Noonavath, Delaney Orcutt, Evan Gross, Katharine A. Collier, Amir Mortazavi, Edmund Folefac, Paul Monk, Yuanquan Yang
J. Cancer 2025; 16(14): 4047-4054. doi:10.7150/jca.113258
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CXCR4 Inhibition Induces Tumor Necrosis by Selectively Targeting the Proliferating Blood Vessels in Oral Squamous Cell Carcinoma
Yamin Soe, Hotaka Kawai, Htoo Shwe Eain, Saori Yoshida, May Wathone Oo, Zin Zin Min, Kiyofumi Takabatake, Keisuke Nakano, Hitoshi Nagatsuka
J. Cancer 2025; 16(14): 4055-4070. doi:10.7150/jca.115847
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Isoliquiritigenin inhibits colorectal cancer progression by targeting the FGFR4/FASN mediated lipid metabolism pathway
Xiaohui Zhai, Huizhi Yang, Zhiqin Tan, Song Wu, Qing Bao, Jian Liang, Hailin Tang
J. Cancer 2025; 16(14): 4071-4080. doi:10.7150/jca.116357
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NCAPH as a potential prognostic signaling biomarker regulating low-grade glioma cell proliferation, migration, invasion, immune microenvironment, and drug sensitivity
Lirui Dai, Shu Jiang, Peizhi Zhou
J. Cancer 2025; 16(14): 4099-4116. doi:10.7150/jca.115870
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Revisiting IGF2BP1 in Endometrial Cancer: Ethnic-Specific Prognostic Implications and Association with Caspase-3 and pSTAT3
Hua Ho, Ching-Yu Shih, Chiao-Yin Cheng, Yao-Jen Liang, Yen-Lin Chen
J. Cancer 2025; 16(14): 4117-4126. doi:10.7150/jca.119549
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Development and validation of a nomogram to predict prognosis of patients with combined hepatocellular-cholangiocarcinoma after hepatic resection
Rongqiang Liu, Sheng Wang, Yesheng Du, Tao Wen, Lei Xiang, Wenyuan Xie, Dewei Li, Hui Li
J. Cancer 2025; 16(14): 4127-4138. doi:10.7150/jca.116790
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Causal Relationship Between Metabolic Traits and Risk of NSCLC: A Two-Sample Mendelian Randomization Analysis
Xin Li, Weifang Cui, Chaojun Duan, Chunfang Zhang
J. Cancer 2025; 16(14): 4139-4146. doi:10.7150/jca.109913
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OCT4-mediated upregulation of DUSP6 promotes metastasis in non-small-cell lung cancer
Bing-Hua Su, Chung-Teng Wang, Chia-Sing Lu, Tang-Hsiu Huang, Tzu-Chun Wu, Yu-Chu Su, Yu-Chih Wu, Yi-Ting Yen, Yau-Lin Tseng, Li-Hsin Cheng, Chi-Won Suk, Ai-Li Shiau, Jia-Ming Chang, Chao-Liang Wu
J. Cancer 2025; 16(14): 4172-4186. doi:10.7150/jca.108663
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Effect of hydrogel-spacer implantation and uneven positioning on rectal dose in intensity-modulated radiotherapy for prostate cancer
Masafumi Uno, Yukihisa Tamaki, Kasumi Nonomura, Unta Yamamori, Hiroshi Burioka, Natsuko Nagano, Atsushi Ue, Yoko Sonoyama, Rika Yoshida, Kazuhiro Kitajima, Koichiro Wada
J. Cancer 2025; 16(14): 4187-4195. doi:10.7150/jca.119694
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Associations of serum lead with colorectal cancer: data from NHANES 1999-2020
Lin Zhong, Yuanhong Peng, Lina Luo, Luji Huang, Fu Cheng, Yan Lu, Yongle Ju, Manzhao Ouyang
J. Cancer 2025; 16(14): 4196-4205. doi:10.7150/jca.117774
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Extrachromosomal circular DNA of multiple myeloma
Fangfang Li, Xinyi Long, Sishi Tang, Jing Liu, Yunfeng Fu
J. Cancer 2025; 16(14): 4206-4218. doi:10.7150/jca.117290
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Integrative Analysis of GEO Datasets and Mendelian Randomization Reveals a Potential Role ofISOC1 in Renal Cell Carcinoma
Jingsong Wang, Yunxun Liu, Zhiwei Yan, Qianxue Lu, Jun Jian, Xiuheng Liu, Zhiyuan Chen, Qingyuan Zheng, Shanshan Wan, Lei Wang
J. Cancer 2025; 16(14): 4219-4232. doi:10.7150/jca.118622
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Exploring the Glycolytic Mechanisms in “Driver Gene-Negative” Lung Adenocarcinoma (LUAD): A Single-Cell RNA Sequencing Approach to Identify the MIF-HIF-1α Axis
Hao-Shuai Yang, Yuan-Hao Li, Qi Chen, Hong-He Luo, Qi-Duo Yu, Yu Han, Weijie Zhu, Jin Zhang, Chao-Yang Liang
J. Cancer 2025; 16(14): 4233-4244. doi:10.7150/jca.119149
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Local Genetic Correlations and Pleiotropy Reveal Shared Genetic Architecture Between COVID-19 Phenotypes and Prostate Cancer in European Populations
Rong Xiang, Xunying Zhao, Lin Chen, Xueyao Wu, Jinyu Xiao, Xia Jiang
J. Cancer 2025; 16(14): 4245-4256. doi:10.7150/jca.111126
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Gene Signature Associated with Ferroptosis for Predicting Overall Survival among Ovarian Cancer Patients
Yanling Li, Yidi Wang, Han Lei, Kai Wai Li, Jingman Tang, Lu Xu, Yan Liu, Jianhong Lu, Yulong Peng, Lili Fan, Xiaojuan Li, Jianbo He
J. Cancer 2025; 16(14): 4257-4269. doi:10.7150/jca.116777
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Capsaicin, the Pungent Component of Red Chili Pepper, induces p21-mediated Cell Cycle Arrest in Renal Cell Carcinoma via Downregulating GLI1: an Experimental Research In Vitro
Long Zheng, Yongchao He, Hao Huang, Wei Qu
J. Cancer 2025; 16(14): 4284-4291. doi:10.7150/jca.119706
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Reviews
From Herb to Hope: A Systematic Exploration of Medicinal Plants' Role in Cancer Therapy
Sahar S. Alghamdi, Ruya Alshkrh, Afrah E. Mohammed, Shuroug A. Alowais
J. Cancer 2025; 16(14): 4081-4098. doi:10.7150/jca.114837
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Regulating arachidonic acid metabolism: a novel strategy to prevent colorectal inflammatory cancer transformation
Sisi Ren, Lu Lu, Hang Su, Zongping Li, Sumei Li, Jiashu Pan, Yujing Liu, Guang Ji, Hanchen Xu
J. Cancer 2025; 16(14): 4155-4171. doi:10.7150/jca.118694
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Molecular Mechanisms and Novel Therapeutics Targeting Ferroptosis in Gastric Cancer: A Literature Review
Hsi-Lung Hsieh, Ming-Chin Yu, Hui-Ching Tseng, Yi-Hsuan Wu, Ming-Ming Tsai
J. Cancer 2025; 16(14): 4270-4283. doi:10.7150/jca.119757
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Short Research Communication
Expression of CX3CL1 in the neoplastic lung tissue of squamous cell lung cancer
Alfonso Salgado-Aguayo, Selma Rivas-Fuentes, Ma. Eugenia Vázquez-Manríquez, Maribel Soto-Nava, César Luna-Rivero, Edgar Sevilla-Reyes, Santiago Ávila-Ríos
J. Cancer 2025; 16(14): 4147-4154. doi:10.7150/jca.116713
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