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Review Tumor Treating Fields in Solid Tumors: A Multiscale Evidence Framework with Gastric Cancer as an Early Translational Case Study Yiwei Yuan, Haohan Zheng, Yipeng Zhang, Yulong Sun, Jianfeng Zhang, Huijuan Li J. Cancer 2026; 17(12): 2019-2041. doi:10.7150/jca.143340 Full text PDF


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Research Paper Systemic Immune Traits and Candidate Genes in Uveal Melanoma: An Exploratory Mendelian Randomization and Transcriptomic Study Jianhui Wang, Qi Zhang, Tengteng Yao, Na Sun, Zhaoyang Wang J. Cancer 2026; 17(12): 2007-2018. doi:10.7150/jca.142907 Full text PDF


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Research Paper Dynamic Postoperative Skeletal Muscle Trajectories Predict Survival in Stage II-III Gastric Cancer Jeong Eun Kim, Song Ee Park, Jin Hwa Choi, In Gyu Hwang J. Cancer 2026; 17(12): 1996-2006. doi:10.7150/jca.142566 Full text PDF


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Research Paper RFC1, RPA1, and POLE expression characterizes the clinical behavior and immune microenvironment of colorectal cancer Michał Gola, Bartłomiej Emil Kraziński, Jacek Kieżun, Hanna Majewska, Janusz Godlewski J. Cancer 2026; 17(12): 1981-1995. doi:10.7150/jca.140797 Full text PDF


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Review Who Should Undergo Surgery, and at What Operative Risk? Two Conditions Governing Cytoreduction in TKI-Treated Gastrointestinal Stromal Tumor Chun-Nan Yeh J. Cancer 2026; 17(11): 1965-1977. doi:10.7150/jca.144312 Full text PDF


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Research Paper Integrative Locus-Resolved Genomics Uncovers Distinct Genetic Links Between Leukocyte Telomere Length and Colon Cancer Susceptibility Aocheng Ji, Wenbin Xu, Yonghui Wu, Yiyi Jin, Wen Lin, Longxin Xiong, Chunyan Zeng J. Cancer 2026; 17(11): 1952-1964. doi:10.7150/jca.142445 Full text PDF

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Tumor Treating Fields in Solid Tumors: A Multiscale Evidence Framework with Gastric Cancer as an Early Translational Case Study

Tumor Treating Fields (TTFields) involve low-intensity, intermediate-frequency alternating electric fields and are most established for glioblastoma. Evidence for other solid tumors is growing, but data for gastric cancer remains limited to a single in vitro FOLFOX-combination study and an exploratory signal from the EF-31 single-arm study, which was reported in a registry and conference abstract without a peer-reviewed patient-outcome paper. We assess ...


Systemic Immune Traits and Candidate Genes in Uveal Melanoma: An Exploratory Mendelian Randomization and Transcriptomic Study

Background: Uveal melanoma (UM) is classified by recurrent genomic alterations and by high-risk, immune-rich tumor states, but the contribution of inherited variation in peripheral immune phenotypes remains unclear. We aimed to identify peripheral immune traits and candidate genes associated with UM and characterize candidate-gene expression in its immune microenvironment. We combined two-sample Mendelian randomization (MR) of 731 immunophenotypes, ...

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