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Review tsRNA's Biological Function and its Potential Application in Disease Diagnosis and Prognosis Full text PDF
Research Paper Long-Term Empagliflozin Treatment (50 Days) Attenuates Protease Activity, Migration, and Stemness-Associated Phenotypes in BFTC-909 Renal Pelvis Transitional Cell Carcinoma Cells Full text PDF
Research Paper A digital polymerase chain reaction method targeting non-recombined T-cell receptor sequences aids in diagnosing primary cutaneous T-cell lymphomas Full text PDF
Research Paper Single-cell Transcriptomics Uncovers the Tumor Microenvironment and Collagen-CD44 Axis in HIV Positive Cervical Squamous Cell Carcinoma Full text PDF
Research Paper Integrative bulk and single-cell transcriptomic analysis identifies an ac4C-related signature in lung adenocarcinoma Full text PDF
Research Paper Cell-Specific DNA Methylation Markers in Plasma cfDNA Reveal Diagnostic Potential for Head and Neck Cancer Full text PDF
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Background: N4-acetylcytidine (ac4C) RNA modification is a critical epitranscriptomic regulator of cancer progression, yet its specific biological functions and regulatory patterns in lung adenocarcinoma (LUAD) remain poorly understood. This study aims to characterize the clinical relevance and potential regulatory patterns of ac4C-related features in the LUAD tumor microenvironment (TME). Methods: We integrated bulk RNA-seq data from TCGA and single-cell ...
Background: Diagnosing primary cutaneous T-cell lymphoma (PCTCL) relies on the comprehensive evaluation of clinical presentation, histopathology, immune profile, and molecular testing. Regarding molecular testing, the BIOMED-2 assay is most commonly used for detecting monoclonality of T-cell receptor (TCR) genes. However, its sensitivity is not ideal for PCTCLs, and a supplementary test is required. We recently found that the ratios of non-recombined ...