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Research Paper
DNA methylation mediated down-regulation of ANGPTL4 promotes colorectal cancer metastasis by activating the ERK pathway
Kunning Zhang, Zhiwei Zhai, Sanshui Yu, Yu Tao
J. Cancer 2021; 12(18): 5473-5485. doi:10.7150/jca.52338
[Abstract] [Full text] [PDF]


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Research Paper
Sirt3 Promoted DNA Damage Repair and Radioresistance Through ATM-Chk2 in Non-small Cell Lung Cancer Cells
Kun Cao, Yuanyuan Chen, Songyun Zhao, Yijuan Huang, Tingting Liu, Hu Liu, Bailong Li, Jianguo Cui, Jianming Cai, Chong Bai, Yanyong Yang, Fu Gao
J. Cancer 2021; 12(18): 5464-5472. doi:10.7150/jca.53173
[Abstract] [Full text] [PDF]


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Research Paper
The Expression of CLDN6 in Hepatocellular Carcinoma Tissue and the Effects of CLDN6 on Biological Phenotypes of Hepatocellular Carcinoma Cells
Yan Lu, Qihua Dang, Yin Bo, Xuejin Su, Liping Wang, Jiaqi Sun, Junyuan Wei, Chengshi Quan, Yanru Li
J. Cancer 2021; 12(18): 5454-5463. doi:10.7150/jca.55727
[Abstract] [Full text] [PDF]


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Research Paper
SLC34A2 Up-regulation And SLC4A4 Down-regulation Correlates With Invasion, Metastasis, And The MAPK Signaling Pathway In Papillary Thyroid Carcinomas
Fengyan Huang, Haitao Wang, Juan Xiao, Chunchun Shao, Yong Zhou, Wei Cong, Maosong Gong, Jingfu Sun, Liqun Shan, Zhanyu Hao, Lihua Wang, Shouluan Ding, Zhigang Yu, Jianing Liu, Hongying Jia
J. Cancer 2021; 12(18): 5439-5453. doi:10.7150/jca.56730
[Abstract] [Full text] [PDF]


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Research Paper
GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer
Sonia Brun, Jean-Marc Pascussi, Elena Patricia Gifu, Eloïne Bestion, Zuzana Macek-Jilkova, Guanxiong Wang, Firas Bassissi, Soraya Mezouar, Jérôme Courcambeck, Philippe Merle, Thomas Decaens, Julie Pannequin, Philippe Halfon, Claude Caron de Fromentel
J. Cancer 2021; 12(18): 5432-5438. doi:10.7150/jca.58533
[Abstract] [Full text] [PDF]


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Research Paper
Serial surveillance by circulating tumor DNA profiling after chimeric antigen receptor T therapy for the guidance of r/r diffuse large B cell lymphoma precise treatment
Linghui Zhou, Houli Zhao, Yang Shao, Xin Chen, Ruimin Hong, Linqin Wang, Fang Ni, Arnon Nagler, Yongxian Hu, He Huang
J. Cancer 2021; 12(18): 5423-5431. doi:10.7150/jca.60390
[Abstract] [Full text] [PDF]


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Research Paper
PSD3 is an oncogene that promotes proliferation, migration, invasion, and G1/S transition while inhibits apoptotic in papillary thyroid cancer
Lingli Jin, Danni Zheng, Adheesh Bhandari, Danxiang Chen, Erjie Xia, Yaoyao Guan, Jialiang Wen, Ouchen Wang
J. Cancer 2021; 12(18): 5413-5422. doi:10.7150/jca.60885
[Abstract] [Full text] [PDF]


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Review
WFDC Protein: A Promising Diagnosis Biomarker of Ovarian Cancer
Chen Zhang, Haoyue Hu, Xiaoyan Wang, Yajuan Zhu, Ming Jiang
J. Cancer 2021; 12(18): 5404-5412. doi:10.7150/jca.57880
[Abstract] [Full text] [PDF]


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Research Paper
MiR-301a-5p/SCIN promotes gastric cancer progression via regulating STAT3 and NF-κB signaling
Yingying Huang, Xiaoxiao Du, Xiangliu Chen, Chuanzhi Chen, Haiyong Wang, Yan Yang, Lisong Teng
J. Cancer 2021; 12(18): 5394-5403. doi:10.7150/jca.59747
[Abstract] [Full text] [PDF]


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Research Paper
Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer
Sang-Soo Park, Yea Seong Ryu, Dong-In Koh, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Mi Jin Kim, Do Yeon Kim, Jun Ki Hong, Eun Ho Kim, Hong-Rae Jeong, Yoon Sun Park, Joseph Kim, Dong Min Kim, Hyeseon Yun, Joo-Yeon Shin, Dong-Hoon Jin
J. Cancer 2021; 12(18): 5385-5393. doi:10.7150/jca.57463
[Abstract] [Full text] [PDF]


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Research Paper
MicroRNA Profiling of Morphologically Heterogeneous Clear Cell Renal Cell Carcinoma
Alessio Giubellino, Christopher J. Ricketts, Vanessa Moreno, W. Marston Linehan, Maria J. Merino
J. Cancer 2021; 12(18): 5375-5384. doi:10.7150/jca.52310
[Abstract] [Full text] [PDF]


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Research Paper
Discrepancy of Breast and Axillary Pathologic Complete Response and Outcomes in Different Subtypes of Node-positive Breast Cancer after Neoadjuvant Chemotherapy
Shin-Cheh Chen, Chi-Chang Yu, Hsien-Kun Chang, Yung-Chang Lin, Yung-Feng Lo, Shih-Che Shen, Wen-Lin Kuo, Hsiu-Pei Tsai, Hsu-Huan Chou, Chia-Hui Chu, Wen-Chi Shen, Ren-Chin Wu, Shir-Hwa Ueng, Yi-Ting Huang
J. Cancer 2021; 12(17): 5365-5374. doi:10.7150/jca.62830
[Abstract] [Full text] [PDF]


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Research Paper
Metronomic vinorelbine is an excellent and safe treatment for advanced breast cancer: a retrospective, observational study
Chien-Ting Liu, Meng-Che Hsieh, Yu-Li Su, Chaio-Ming Hung, Sung-Nan Pei, Chun-Kai Liao, Yu-Fen Tsai, Hsiu-Yun Liao, Wei-Ching Liu, Chong-Chi Chiu, Shih-Chung Wu, Shih-Ho Wang, Ching-Ting Wei, Kun-Ming Rau
J. Cancer 2021; 12(17): 5355-5364. doi:10.7150/jca.60682
[Abstract] [Full text] [PDF]


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Research Paper
FHL1 Inhibits the Progression of Colorectal Cancer by Regulating the Wnt/β-Catenin Signaling Pathway
Yujing Liu, Chunyan Wang, Peiqiu Cheng, Shengan Zhang, Wenjun Zhou, Yangxian Xu, Hanchen Xu, Guang Ji
J. Cancer 2021; 12(17): 5345-5354. doi:10.7150/jca.60543
[Abstract] [Full text] [PDF]


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Research Paper
Dyslipidemia in Chinese Pancreatic Cancer Patients: A Two-Center Retrospective Study
Feiyang Wang, Li Huang, Jinyan Zhang, Junwei Fan, Heshui Wu, Junming Xu
J. Cancer 2021; 12(17): 5338-5344. doi:10.7150/jca.60340
[Abstract] [Full text] [PDF]


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Research Paper
Prognostic Value of KRAS Exon 3 and Exon 4 Mutations in Colorectal Cancer Patients
Tianan Guo, Yuchen Wu, Dan Huang, Yutong Jin, Weiqi Sheng, Sanjun Cai, Xiaoyan Zhou, Xiaoli Zhu, Fangqi Liu, Ye Xu
J. Cancer 2021; 12(17): 5331-5337. doi:10.7150/jca.59193
[Abstract] [Full text] [PDF]

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