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Research Paper Vemurafenib Induces Apoptosis via JNK Activation and AKT Inhibition in Hepatocellular Carcinoma Full text PDF
Research Paper Serum Thyroid Biomarkers for Diagnosing Malignant Thyroid Nodules: A Machine Learning Approach with External and Causal Validation Full text PDF
Research Paper MRI-Based Habitat Radiomics for Differentiating Early-Stage Endometrial Carcinoma from Submucous Leiomyoma: A Multicenter Validation Study Full text PDF
Research Paper Integrative Bulk and Single-Cell Transcriptome Profiling of Telomere-Related Genes Reveals a Robust Prognostic Signature and Immunotherapeutic Landscape in Neuroblastoma Full text PDF
Research Paper Ganoderma lucidum alcohol extract targets mutant p53 signaling to inhibit proliferation in triple-negative breast brain metastasis cancer Full text PDF
Research Paper Functional Stratification and Long-Term Care Service Patterns among Discharged Patients with Cancer: A Retrospective Study from Taiwan Full text PDF
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Background: As cancer survival improves, a growing number of patients experience functional decline and require supportive care and long-term care after hospitalization. However, the relationship between functional severity and post-discharge long-term care utilization in patients with cancer remains insufficiently characterized. This study examined long-term care service patterns across functional severity levels, as classified by a Case-Mix System, ...
Background: Thyroid nodules (TNs) are common, and accurate malignancy risk stratification is critical for clinical decision-making. Although serum thyroid biomarkers are routinely measured, their contribution to malignancy discrimination remains insufficiently characterized. Thus, we aimed to develop a practical and biologically grounded model for identifying malignant TNs using routinely clinical data. Methods: We retrospectively analyzed 5537 patients ...