Impact Factor ISSN: 1837-9664
Research Paper Integrative Locus-Resolved Genomics Uncovers Distinct Genetic Links Between Leukocyte Telomere Length and Colon Cancer Susceptibility Full text PDF
Research Paper [177Lu]Lu-PSMA-617-Mediated Endoradiotherapy of Breast Cancer by Targeting Tumor-Associated Neovasculature Full text PDF
Review Delayed First Childbirth Reshapes Postpartum Breast Cancer Risk: A Biphasic Model Full text PDF
Research Paper Real-World Comparative Survival Outcomes of First-Line Serplulimab Plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer: A Single-Center Retrospective Cohort Study Full text PDF PubMed PMC
Research Paper An Eight-Gene Metabolic Prognostic Signature in Head and Neck Squamous Cell Carcinoma: Cross-Cohort Evaluation, Single-Cell Analysis, and Preliminary Functional Evaluation of PYGL and G6PD Full text PDF PubMed PMC
Research Paper FLNA Expression in Cancer-Associated Fibroblasts Is Associated with Immunosuppression and Tumor Progression in Colorectal Cancer Full text PDF PubMed PMC
Issue 10; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Delayed First Childbirth Reshapes Postpartum Breast Cancer Risk: A Biphasic Model
Delayed first childbirth (35-39 y) is a rapidly rising global exposure that reshapes postpartum breast cancer (PPBC) risk in a biphasic manner: a prolonged short-term risk peak (hazard ratio 1.40 at 6.4 years postpartum) coupled with long-term protection delayed beyond 15 years. Synthesizing 15 prospective cohorts with single-cell and spatial atlases of the aging parous mammary gland, we propose that maternal age is a dual modifier of PPBC risk. First, ...
Background: Head and neck squamous cell carcinoma (HNSCC) is the most prevalent pathological subtype of head and neck malignancies. Although metabolic reprogramming contributes to malignant progression and adaptation within the tumor microenvironment in HNSCC, its biological and prognostic implications remain incompletely understood. Objective: To develop and evaluate a metabolism-related prognostic score for head and neck squamous cell carcinoma ...