Impact Factor ISSN: 1837-9664
Research Paper The scPagwas analysis of single-cell sequencing combined with Bayesian deconvolution with SMR Reveals Tumor Heterogeneity and Predicts Immunotherapy Response in Neuroblastoma Full text PDF
Research Paper LH2 Promotes Tumor Progression in Oral Squamous Cell Carcinoma via EPHA7-AKT-VEGF Signaling Full text PDF
Research Paper EfficientNetB5-Based Deep Learning for Automated Cancer Detection in Tissue Microarray Images Full text PDF
Review Molecular mechanism and potential role of mitophagy in breast cancer Full text PDF
Review A candidate PPARγ to GPX4 axis in ferroptosis suppression and platinum resistance in bladder cancer: evidence appraisal and a testable research agenda Full text PDF
Research Paper Exosomes from Cancer-associated Fibroblasts Orchestrate Lung Metastasis of Breast Cancer via LncRNA LMAEP Full text PDF
Issue 10; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Objective: High-risk neuroblastoma, the predominant driver of pediatric cancer deaths, is marked by marked intratumoral heterogeneity that fuels therapy resistance. To predict response to and targets for immunotherapy, we use single-cell and bulk RNA sequencing data to reveal tumor heterogeneity in neuroblastoma, and to identify prognostic genes for neuroblastoma. Methodology: Single-cell data were analyzed for trait-associated subpopulations and ...
Molecular mechanism and potential role of mitophagy in breast cancer
Breast cancer remains the most commonly diagnosed malignancy among women worldwide and a leading cause of cancer related mortality in this population. Mitochondrial dysfunction is increasingly recognized as a hallmark of breast cancer, contributing to tumor initiation, progression, and therapeutic resistance. Mitophagy, a selective form of autophagy that eliminates damaged or dysfunctional mitochondria, is essential for maintaining cellular and mitochondrial ...