Impact Factor ISSN: 1837-9664
Research Paper Exosomes from Cancer-associated Fibroblasts Orchestrate Lung Metastasis of Breast Cancer via LncRNA LMAEP Full text PDF
Research Paper Radiation-induced SLAMF1 reconfigures the SLAM family receptors landscape in triple-negative breast cancer cells Full text PDF
Research Paper Per-patient Comparison of [68Ga]-FAPI-46 Versus [18F]FDG as PET Tracers in ER-positive Breast Cancer: Study Design of a Single-centre Prospective Study Full text PDF
Research Paper Prognostic value of neuro-related genes in colorectal cancer and their potential implications for immunotherapy Full text PDF
Research Paper Bevacizumab or Aflibercept in Combination with Second-Line FOLFIRI after Progression on FOLFOX Plus Bevacizumab in Metastatic Colorectal Cancer: A Comparative Study Full text PDF
Review Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer Full text PDF
Issue 9; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Lung metastasis is a leading cause of patient mortality in breast cancer. Cancer-associated fibroblasts (CAFs), the most abundant stromal cells within the tumor microenvironment, are closely implicated in pulmonary metastasis. Nevertheless, the mechanism underlying CAF-mediated metastasis remains elusive. We found that density of CAFs in primary tumors showed no significant difference in patients with or without lung metastasis. However, CAFs of breast ...
Background: The optimal anti-angiogenic strategy in the second-line treatment of metastatic colorectal cancer (mCRC) after progression on first-line FOLFOX plus bevacizumab remains unclear. We aimed to compare the efficacy and safety of FOLFIRI combined with bevacizumab or aflibercept in this well-defined clinical setting. Methods: In this retrospective single-center study, 152 patients with mCRC who progressed after at least four cycles of first-line ...