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Research Paper Targeting MUC16 to Reverse Anoikis Resistance: A Promising Strategy for Metastatic Lung Adenocarcinoma Therapy Kulsoom, Wajahat Ali, Zhe Ma, Wen Cai, Zhenlong Wang, Fu Wang J. Cancer 2026; 17(4): 819-834. doi:10.7150/jca.131494 Full text PDF


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Research Paper Longitudinal CT-based deep learning radiomics for predicting prognosis in esophageal squamous cell carcinoma treated with definitive chemoradiotherapy: a two-center study Xinyang Hu, Wubulaishan Maitudi, Xi Chen, Lina Zhao, Qingsong Pang J. Cancer 2026; 17(4): 808-818. doi:10.7150/jca.126804 Full text PDF


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Research Paper Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer Bing Ang, Yi Bai, Xiyue Deng, Qiong Wu, Yuqian Wang, Shanshan Xu, Weixin Zhang, Yang Li, Dapeng Chen, Ruixi Li, Siyang Li, Zhigang Zhao, Yamin Zhang J. Cancer 2026; 17(4): 797-807. doi:10.7150/jca.127225 Full text PDF


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Research Paper WISP-3 promotes angiogenesis in non-small cell lung cancer through p38/JNK-c-Jun-mediated PDGF-A upregulation En-Ming Chang, Syuan-Ling Lin, Ching-Yuan Cheng, Chih-Hsin Tang, Yu-Chen Chen, Chiang-Wen Lee, Chih-Yang Lin J. Cancer 2026; 17(4): 787-796. doi:10.7150/jca.127681 Full text PDF


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Research Paper High PMS2 Expression-Based Nomogram for Risk Stratification in Resected Hepatocellular Carcinoma: Application to Recurrence and Neoadjuvant Therapy Selection Wenchen Gong, Ruyu Han, Liyu Sun, Yingrui Gao, Zhiqiang Han, Yimeng Wang, Yuren Xia, Yukun Wei, Tianqiang Song, Lu Chen, Xiangdong Tian J. Cancer 2026; 17(4): 771-786. doi:10.7150/jca.131997 Full text PDF


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Review Roles of Cellular Neighborhoods in Lung Cancer Rui Bai, Wenjie Sun J. Cancer 2026; 17(4): 759-770. doi:10.7150/jca.132848 Full text PDF

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Issue 3; 2026

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Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...


WISP-3 promotes angiogenesis in non-small cell lung cancer through p38/JNK-c-Jun-mediated PDGF-A upregulation

Angiogenesis is a pivotal process for tumor progression and metastasis in non-small cell lung cancer (NSCLC). However, the molecular mechanisms by which WNT1-inducible signaling pathway protein 3 (WISP-3) contributes to NSCLC angiogenesis remain poorly defined. This study investigated the role of WISP-3 in regulating pro-angiogenic signaling in lung adenocarcinoma (LUAD) cells. Conditioned medium from H1299 and A549 cells treated with recombinant ...


Therapeutic Targeting of Oxidative Phosphorylation in Microsatellite Instability-High Gastric Cancer

Background: Gastric cancer is the third leading cause of cancer-related mortality worldwide. According to The Cancer Genome Atlas (TCGA), it can be classified into four molecular subtypes, including microsatellite instability (MSI) and genomically stable (GS) subtypes, which display distinct clinical and pathological features. However, differences in their tumor microenvironment, particularly metabolic reprogramming, remain poorly understood. Methods: ...

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