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Research Paper PKM2 is the Metabolic Checkpoint for Stemness Features in Head and Neck Cancer Full text PDF
Review Field cancerization in urothelial carcinoma: molecular alterations and clinical implications Full text PDF
Research Paper Mitochondrial Parameters influence Chemosensitivity in Gastric Cancer Cells Full text PDF
Review Environmental co-exposure to microplastics and phenol may influence redox signaling and tumor microenvironment dynamics Full text PDF
Research Paper Potential influence of long non-coding RNA NEAT1 genetic variants and expression levels on the progression of prostate cancer Full text PDF
Review Mitochondrial Dysfunction as a Targetable Vulnerability in Gastric Cancer: From Carcinogenesis to Apoptosis (A Narrative Review) Full text PDF
Issue 8; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Gastric cancer (GC) remains a major global health burden and is associated with high mortality worldwide. Current treatment integrates surgery, perioperative or systemic chemotherapy, molecularly targeted therapy, and immune checkpoint blockade; however, efficacy is frequently limited by intratumoral heterogeneity, metabolic plasticity, and therapeutic resistance. Mitochondria, as central regulators of cellular bioenergetics, redox homeostasis, and ...
Field cancerization in urothelial carcinoma: molecular alterations and clinical implications
Urothelial carcinoma (UC) is a common malignancy of the urinary tract and is characterized by frequent recurrence, particularly in patients with non-muscle-invasive disease. Recurrence has traditionally been explained by residual tumor cells, intraluminal seeding, or the outgrowth of disseminated clones. However, molecular studies have shown that urothelium that appears normal under routine histological examination may already harbor cancer-related ...