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Research Paper Mutation Patterns Define Clinical Heterogeneity in Acute Myeloid Leukemia Full text PDF
Research Paper Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis Full text PDF
Research Paper PKM2 is the Metabolic Checkpoint for Stemness Features in Head and Neck Cancer Full text PDF
Review Field cancerization in urothelial carcinoma: molecular alterations and clinical implications Full text PDF
Research Paper Mitochondrial Parameters influence Chemosensitivity in Gastric Cancer Cells Full text PDF
Review Environmental co-exposure to microplastics and phenol may influence redox signaling and tumor microenvironment dynamics Full text PDF
Issue 8; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Mutation Patterns Define Clinical Heterogeneity in Acute Myeloid Leukemia
Background: Acute myeloid leukemia (AML) is a molecularly heterogeneous malignancy where next-generation sequencing (NGS) has revolutionized risk stratification and treatment paradigms. However, the interplay between mutation cooperativity, clinical phenotypes, and biochemical markers of organ dysfunction remains poorly characterized. This study investigates how co-mutational patterns influence hematological/biochemical parameters and survival outcomes ...
Environmental exposure patterns have shifted from single-compound exposure to complex co-exposure scenarios. Among widespread pollutants, microplastics (MPs) and phenol may interact biologically despite their distinct physicochemical properties. Phenol is associated with oxidative stress-related toxicity, whereas MPs may serve as potential carriers and redox-active modifiers. This review proposes that MP-induced oxidative stress and phenol-mediated ...