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Review Development of nasopharyngeal carcinoma target delineation: from two-dimensional radiotherapy to adaptive precision radiotherapy Xiaojing Yang, Lijun Liu, Huicai Zhang, Hanru Ren, Jie Fu J. Cancer 2026; 17(6): 1179-1186. doi:10.7150/jca.125480 Full text PDF


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Research Paper Dehydroleucodine Induces ROS-Mediated Mitochondrial Apoptosis and G2/M Cell Cycle Arrest in Oral Squamous Cell Carcinoma Johnathon Lee, Tsung-Ming Chang, Chia-Jung Lee, Ju-Fang Liu, Hsin-Hua Chou J. Cancer 2026; 17(6): 1165-1178. doi:10.7150/jca.127924 Full text PDF


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Review The Emerging Role of CACNA1E in Cancer: Molecular Mechanisms and Therapeutic Implications Wei Hou J. Cancer 2026; 17(6): 1155-1164. doi:10.7150/jca.133409 Full text PDF


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Research Paper Development and Validation of an m6A-Derived Prognostic Signature in Lung Adenocarcinoma Zheng Shao, YongLi Situ, Bairu Lai, Ying Xu, Jv Chen, Li Deng, QinYing Xu, Meng Liang, Zhu Liang, ZhanQiang Xie J. Cancer 2026; 17(6): 1134-1154. doi:10.7150/jca.134792 Full text PDF


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Research Paper Epidemiological Trends and Shared Molecular Signatures of Pancreatic Ductal Adenocarcinoma and Diabetes: An Integrative Analysis Based on Global Burden of Disease and Gene Expression Omnibus Datasets Jiaxi Zhang, Zhibin Liu, Ke Huang, Junkoo Yi, Myoung Ok Kim J. Cancer 2026; 17(6): 1125-1133. doi:10.7150/jca.134528 Full text PDF


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Research Paper CellVizio® System for Mesothorax Lymphadenopathy Rapid on Site, 18G needle: Pros and Cons Paul Zarogoulidis, Wolfgang Hofenforst-Schwidt, Haidong Huang, Stavros Tryfon, Yifei Zhang, Xiaping Shen, Guoren Ma, Kyriakos Amarantidis, Elena Maragouli, Vasilis Papadopoulos, Eleni-Isidora Perdikouri, Vagelis Voulgaris, Lutz Freitag, Chrysoula Margioula-Siarkou, Theodora Tsiouda, Paschalis Ntolios, Stamatis Petousis, Konstantina Triantafylopoulou, Kosmas Tsakiridis, Nikolaos Courcoutsakis, Sofia Baka, Dimitris Baloukas, Paschalis Steiropoulos, Bojan Zaric, Xiaping Shen J. Cancer 2026; 17(6): 1117-1124. doi:10.7150/jca.136122 Full text PDF

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Development of nasopharyngeal carcinoma target delineation: from two-dimensional radiotherapy to adaptive precision radiotherapy

Nasopharyngeal carcinoma (NPC) is mainly treated with radiotherapy. With the advancements of imaging and radiotherapy techniques, the delineation of NPC target areas has evolved from empirical field setting in the two-dimensional era to three-dimensional conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT), and image-guided adaptive radiotherapy (ART), significantly improving treatment accuracy and safety. This review systematically ...


Development and Validation of an m6A-Derived Prognostic Signature in Lung Adenocarcinoma

Background: Lung adenocarcinoma (LUAD) exhibits extensive molecular heterogeneity and poor prognosis, necessitating novel epigenetic biomarkers. N6-methyladenosine (m6A) modification, a pivotal epigenetic regulator of RNA, is frequently dysregulated in LUAD, yet its systematic roles in clinical prognosis and the tumor microenvironment (TME) remain poorly elucidated. Methods: Transcriptomic profiles and clinical data from large-scale cohorts were integrated ...

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