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Research Paper Vemurafenib Induces Apoptosis via JNK Activation and AKT Inhibition in Hepatocellular Carcinoma Full text PDF
Research Paper Serum Thyroid Biomarkers for Diagnosing Malignant Thyroid Nodules: A Machine Learning Approach with External and Causal Validation Full text PDF
Research Paper MRI-Based Habitat Radiomics for Differentiating Early-Stage Endometrial Carcinoma from Submucous Leiomyoma: A Multicenter Validation Study Full text PDF
Research Paper Integrative Bulk and Single-Cell Transcriptome Profiling of Telomere-Related Genes Reveals a Robust Prognostic Signature and Immunotherapeutic Landscape in Neuroblastoma Full text PDF
Research Paper Ganoderma lucidum alcohol extract targets mutant p53 signaling to inhibit proliferation in triple-negative breast brain metastasis cancer Full text PDF
Research Paper Functional Stratification and Long-Term Care Service Patterns among Discharged Patients with Cancer: A Retrospective Study from Taiwan Full text PDF
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Triple-negative breast cancer (TNBC) is among the most aggressive subtypes of breast cancer, frequently characterized by invasive growth, metastasis, and poor clinical outcomes. Brain metastasis, commonly observed in TNBC patients, significantly worsens prognosis and survival rates. Current therapeutic strategies for TNBC brain metastases remain limited and largely ineffective. Mutant p53, common in TNBC, promotes malignancy and metastasis. MDA-MB-231 ...
Objective: This study aimed to investigate the utility of magnetic resonance imaging (MRI)-based habitat radiomics for preoperatively distinguishing early-stage endometrial carcinoma (EC) from submucous leiomyoma (SML). Materials and Methods: A retrospective study was conducted on uterine lesions patients who underwent MRI from three hospitals. The k-means clustering algorithm was applied to segment the MRI into distinct habitats based on T1-weighted ...