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Research Paper Bevacizumab or Aflibercept in Combination with Second-Line FOLFIRI after Progression on FOLFOX Plus Bevacizumab in Metastatic Colorectal Cancer: A Comparative Study Okan Aydin, Sermin Dinc Sonusen, Asli Buyukkuscu, Seyyit Bayram Sahin, Serhat Kalkan, Ahmet Emin Ozturk, Mert Erciyestepe, Fatih Atalah, Zehra Sucuoglu Isleyen, Emir Celik, Kayhan Erturk, Muhammed Mustafa Atci J. Cancer 2026; 17(10): 1733-1743. doi:10.7150/jca.138530 Full text PDF


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Review Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer Yuan Zhu, Jia Shang, Xin Zhang, Sheng Tu, Gang Li, Shenjuan Li, Hongwei Peng, Haoli Ma, Fangjin Chen, Wan Xiang, Cong Zou, Yu Xiao, Zilin Xu, Kaiyu Qian, Gang Wang J. Cancer 2026; 17(10): 1720-1732. doi:10.7150/jca.138160 Full text PDF


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Research Paper Associations of HMGA2 single-nucleotide polymorphisms with clinicopathological features of tongue squamous cell carcinoma in Taiwanese men with distinct lifestyle-related risk factors Yi-Chieh Yang, Chia-Hwa Lee, Yi-Fang Ding, Chiao-Wen Lin, Lun-Ching Chang, Yu-Ching Wen, Shun-Fa Yang, Ming-Hsien Chien J. Cancer 2026; 17(10): 1709-1719. doi:10.7150/jca.139096 Full text PDF


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Research Paper Separability of histopathology foundation model embeddings of stimulated Raman histology images for lung carcinoma subtyping Karl-Moritz Schröder, Uyen-Thao Le, Birte Ohm, Till Nicke, Martin Peter Pichotka, Martin Werner, Jürgen Beck, Jakob Straehle, Rainer Schmelzeisen, Leonard Brandenburg, Peter Bronsert, Andreas Weber-Steinhilber J. Cancer 2026; 17(10): 1698-1708. doi:10.7150/jca.135384 Full text PDF


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Review Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges Haixia Gao, Yuan Fang, Pingjing Zhang, Qijun Qian J. Cancer 2026; 17(9): 1684-1697. doi:10.7150/jca.134677 Full text PDF


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Review Regulatory roles of E3 ubiquitin ligase RNF128 in inflammatory diseases and tumors Qiuxiang Xiao, Qidong Liu, Jing Wei, Dalang Yu J. Cancer 2026; 17(9): 1671-1683. doi:10.7150/jca.138010 Full text PDF

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Issue 9; 2026

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Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...


Separability of histopathology foundation model embeddings of stimulated Raman histology images for lung carcinoma subtyping

Histopathology foundation models trained on hematoxylin and eosin (H&E) whole-slide images have recently emerged as versatile encoders for downstream diagnostic tasks, but their transferability to out-of-domain imaging modalities such as stimulated Raman histology (SRH) is unknown. Here, we retrospectively evaluated whether embeddings from histopathology foundation models enable intraoperative SRH-based classification of lung cancer patients into ...


Bevacizumab or Aflibercept in Combination with Second-Line FOLFIRI after Progression on FOLFOX Plus Bevacizumab in Metastatic Colorectal Cancer: A Comparative Study

Background: The optimal anti-angiogenic strategy in the second-line treatment of metastatic colorectal cancer (mCRC) after progression on first-line FOLFOX plus bevacizumab remains unclear. We aimed to compare the efficacy and safety of FOLFIRI combined with bevacizumab or aflibercept in this well-defined clinical setting. Methods: In this retrospective single-center study, 152 patients with mCRC who progressed after at least four cycles of first-line ...

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