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Volume 11 (14); 2020

Research Papers

Role of the E3 Ubiquitin Ligase TRIM4 in Predicting the Prognosis of Hepatocellular Carcinoma
Zhao-Ru Dong, Wei Zhou, Dong Sun, Yu-Chuan Yan, Chun-Cheng Yang, Ya-Fei Yang, Hai-Chao Li, Xu-Ting Zhi, Tao Li
J. Cancer 2020; 11(14): 4007-4014. doi:10.7150/jca.37164
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Gonadotropin-releasing hormone agonists, anti-androgens and the risk of cardio-cerebrovascular disease in prostate cancer patients: an asian population-based observational study
Jong-Mi Seong, Dongho Shin, Jae Woo Sung, Shinjay Cho, Jonghyup Yang, Sungmin Kang, Hyong Woo Moon, Kyu Won Lee, U-Syn Ha
J. Cancer 2020; 11(14): 4015-4022. doi:10.7150/jca.38237
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Development and Validation of an Individualized Nomogram for Predicting Survival in Patients with Esophageal Carcinoma after Resection
Feng Du, Zhiwei Sun, Jun Jia, Ying Yang, Jing Yu, Youwu Shi, Bo Jia, Jiuda Zhao, Xiaodong Zhang
J. Cancer 2020; 11(14): 4023-4029. doi:10.7150/jca.40767
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Silencing of Wwox Increases Nuclear Import of Dvl proteins in Head and Neck Cancer
Asuman Celebi, Ceren Orhan, Betul Seyhan, Nur Buyru
J. Cancer 2020; 11(14): 4030-4036. doi:10.7150/jca.40840
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Plasma exo-hsa_circRNA_0056616: A potential biomarker for lymph node metastasis in lung adenocarcinoma
Fei He, Xuejing Zhong, Zheng Lin, Jianbo Lin, Minglian Qiu, Xu Li, Zhijian Hu
J. Cancer 2020; 11(14): 4037-4046. doi:10.7150/jca.30360
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Xanthohumol suppresses glioblastoma via modulation of Hexokinase 2 -mediated glycolysis
Jian Yuan, Gang Peng, Gelei Xiao, Zhuanyi Yang, Jun Huang, Qing Liu, Zhiquan Yang, Dingyang Liu
J. Cancer 2020; 11(14): 4047-4058. doi:10.7150/jca.33045
[Abstract] [Full text] [PDF] [PubMed] [PMC]

HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment
Young-Dae Kim, Sang-Min Park, Hae Chan Ha, A Reum Lee, Heeyoung Won, Hyunju Cha, Sangsook Cho, Joong Myung Cho
J. Cancer 2020; 11(14): 4059-4072. doi:10.7150/jca.44622
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Quantitative proteomic analysis of bile in extrahepatic cholangiocarcinoma patients
Kuk Hui Son, Chi Bum Ahn, Hyo Jung Kim, Jae Seon Kim
J. Cancer 2020; 11(14): 4073-4080. doi:10.7150/jca.40964
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Expression of Perilipin Family Proteins can be used as Diagnostic Markers of Liposarcoma and to Differentiate Subtypes
Qiaochu Zhang, Pengpeng Zhang, Bingcheng Li, Hongwei Dang, Jinfang Jiang, Lian Meng, Haijun Zhang, Yangyang Zhang, Xiaomeng Wang, Qianru Li, Yang wang, Chunxia Liu, Feng Li
J. Cancer 2020; 11(14): 4081-4090. doi:10.7150/jca.41736
[Abstract] [Full text] [PDF] [PubMed] [PMC]

High Fat High Calories Diet (HFD) Increase Gut Susceptibility to Carcinogens by Altering the Gut Microbial Community
Heiying Jin, Chunxia Zhang
J. Cancer 2020; 11(14): 4091-4098. doi:10.7150/jca.43561
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Use of eribulin as an earlier-line chemotherapy for patients with HER2-negative metastatic breast cancer
Sumito Shingaki, Takahiro Kogawa, Mototsugu Shimokawa, Kenichi Harano, Yoichi Naito, Shota Kusuhara, Yumi Fujimoto, Nobuaki Matsubara, Ako Hosono, Hirofumi Mukai, Tatsuya Onishi, Takashi Hojo, Toru Mukohara
J. Cancer 2020; 11(14): 4099-4105. doi:10.7150/jca.37670
[Abstract] [Full text] [PDF] [PubMed] [PMC]

microRNA Expression Profiling in Young Prostate Cancer Patients
Vladimir A. Valera, Rafael Parra-Medina, Beatriz A. Walter, Peter Pinto, Maria J Merino
J. Cancer 2020; 11(14): 4106-4114. doi:10.7150/jca.37842
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Adjuvant transarterial chemoembolization following radical resection for intrahepatic cholangiocarcinoma: A multi-center retrospective study
Lei Wang, Zi-Guo Lin, Qiao Ke, Jian-Ying Lou, Shu-Guo Zheng, Xin-Yu Bi, Jian-Ming Wang, Wei Guo, Fu-Yu Li, Jian Wang, Ya-Min Zheng, Jing-Dong Li, Shi Cheng, Wei-Ping Zhou, Yong-Yi Zeng
J. Cancer 2020; 11(14): 4115-4122. doi:10.7150/jca.40358
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Ligand-independent EphB1 signaling mediates TGF-β-activated CDH2 and promotes lung cancer cell invasion and migration
Lujuan Wang, Qiu Peng, Buqing Sai, Leliang Zheng, Jiaqi Xu, Na Yin, Xiang Feng, Juanjuan Xiang
J. Cancer 2020; 11(14): 4123-4131. doi:10.7150/jca.44576
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Prediction of Survival in Hepatocellular Carcinoma Based on A Four Long Non-coding RNAs Expression Signature
Zongxing Yang, Yuhan Yang, Gang Zhou, Yan Luo, Wenjun Yang, Youliang Zhou, Jin Yang
J. Cancer 2020; 11(14): 4132-4144. doi:10.7150/jca.40621
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Predictive value of hypoxia, metabolism and immune factors for prognosis in hepatocellular carcinoma: a retrospective analysis and multicenter validation study
Peng Lin, Dong-yue wen, Gang Chen, Yi-wu Dang, Yun He, Hong Yang
J. Cancer 2020; 11(14): 4145-4156. doi:10.7150/jca.41983
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Outcomes of Adjuvant Oral versus Intravenous Fluoropyrimidines for High-Risk Stage II or Stage III Colon Adenocarcinoma: A Propensity Score-Matched, Nationwide, Population-Based Cohort Study
Jiaqiang Zhang, Yu-Chun Yen, Lei Qin, Chia-Lun Chang, Kevin Sheng-Po Yuan, Alexander T.H. Wu, Szu-Yuan Wu
J. Cancer 2020; 11(14): 4157-4165. doi:10.7150/jca.42404
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Improving stereotactic radiotherapy (SRT) planning process for brain metastases by Cyberknife system: reducing dose distribution in healthy tissues
Yu Xuyao, Yuan Zhiyong, Wang Yuwen, Yu Hui, Song Yongchun, Dong Yang, Zhao LuJun, Wang Ping
J. Cancer 2020; 11(14): 4166-4172. doi:10.7150/jca.41102
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Overexpression of Citron Rho-Interacting Serine/Threonine Kinase Associated with Poor Outcome in Bladder Cancer
Jiafeng Shou, Chong Yu, Dahong Zhang, Qi Zhang
J. Cancer 2020; 11(14): 4173-4180. doi:10.7150/jca.43435
[Abstract] [Full text] [PDF] [PubMed] [PMC]

TOP2A Promotes Tumorigenesis of High-grade Serous Ovarian Cancer by Regulating the TGF-β/Smad Pathway
Yan Gao, Hongyu Zhao, Meng Ren, Qi Chen, Jie Li, Zhefeng Li, Chenghong Yin, Wentao Yue
J. Cancer 2020; 11(14): 4181-4192. doi:10.7150/jca.42736
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Prognostic Value of Neutrophil-to-lymphocyte Ratio and Monocyte-to-lymphocyte Ratio in Metastatic Gastric Cancer Treated with Systemic Chemotherapy
Danyang Zhou, Ying Wu, Ying Zhu, Zhenyu Lin, Dandan Yu, Tao Zhang
J. Cancer 2020; 11(14): 4205-4212. doi:10.7150/jca.39575
[Abstract] [Full text] [PDF] [PubMed] [PMC]

High expression of folate cycle enzyme MTHFD1L correlates with poor prognosis and increased proliferation and migration in colorectal cancer
Zhongyun He, Xia Wang, Huizhong Zhang, Baoxia Liang, Jinling Zhang, Zhenfeng Zhang, Yi Yang
J. Cancer 2020; 11(14): 4213-4221. doi:10.7150/jca.35014
[Abstract] [Full text] [PDF] [PubMed] [PMC]

circNFIC suppresses breast cancer progression by sponging miR-658
Gaosheng Xu, Dongmei Ye, Qiang Zhao, Rongfang He, Wei Ma, Yuxuan Li, Shujie Tang, Zhiwei Zhou, Xing Li, Zhiwei Zhang
J. Cancer 2020; 11(14): 4222-4229. doi:10.7150/jca.38830
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Circular RNA HIPK3 is a Prognostic and Clinicopathological Predictor in Malignant Tumor Patients
Gao Wenzhe, Xu Jiahao, Peng Cheng, Zhu Hongwei, Yu Xiao
J. Cancer 2020; 11(14): 4230-4239. doi:10.7150/jca.40001
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prognostic value of stem cell markers in esophageal and esophagogastric junction cancer: a meta-analysis
Elisabetta Trevellin, Giovanni Pirozzolo, Matteo Fassan, Roberto Vettor
J. Cancer 2020; 11(14): 4240-4249. doi:10.7150/jca.33699
[Abstract] [Full text] [PDF] [PubMed] [PMC]

IL-2 enhanced MHC class I expression in papillary thyroid cancer with Hashimoto's thyroiditis overcomes immune escape in vitro
Jia-Qian Hu, Bo-Wen Lei, Duo Wen, Ben Ma, Ting-Ting Zhang, Zhong-Wu Lu, Wen-Jun Wei, Yu-Long Wang, Yu Wang, Duan-Shu Li, Qing-Hai Ji, Tian Liao
J. Cancer 2020; 11(14): 4250-4260. doi:10.7150/jca.38330
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells
Yin-Yu Zhang, Lin-Ming Luo, Yu-Xiang Wang, Neng Zhu, Tan-Jun Zhao, Li Qin
J. Cancer 2020; 11(14): 4261-4273. doi:10.7150/jca.42285
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A Panel of Four-lncRNA Signature as a Potential Biomarker for Predicting Survival in Clear Cell Renal Cell Carcinoma
Haoran Liu, Tao Ye, Xiaoqi Yang, Peng Lv, Xiaoliang Wu, Hui Zhou, Jin Zeng, Kun Tang, Zhangqun Ye
J. Cancer 2020; 11(14): 4274-4283. doi:10.7150/jca.40421
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

Multiple Mechanisms Involving in Radioresistance of Nasopharyngeal Carcinoma
Yuting Zhan, Songqing Fan
J. Cancer 2020; 11(14): 4193-4204. doi:10.7150/jca.39354
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Aberrant LncRNA Expression in Leukemia
Jie Gao, Fujue Wang, Pengqiang Wu, Yingying Chen, Yongqian Jia
J. Cancer 2020; 11(14): 4284-4296. doi:10.7150/jca.42093
[Abstract] [Full text] [PDF] [PubMed] [PMC]