Journal of Cancer
ISSN: 1837-9664
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ISSN: 1837-9664
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Volume 16 (8); 2025
Research Papers
Pair-matched analysis of Circulating Melanoma Cells (CMCs) before and after Immunotherapy in Relation to other Melanoma-Specific Biomarkers
Paula Sawerska, Aneta Konwerska, Łukasz Galus, Agata Kolecka-Bednarczyk, Karolina Buszka, Damian Rusek, Agnieszka Seraszek-Jaros, Michał Nowicki, Jacek Mackiewicz, Joanna Budna-Tukan
J. Cancer 2025; 16(8): 2421-2433. doi:10.7150/jca.102131
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circSLC39A8 by sponging hsa-miR-11181-5p and direct binding to PIK3CA mRNA promotes retinoblastoma proliferation
Jian Gong, Zicheng Song, Jiandong Pan, Xiangwei Huang, Xiaofen Feng, Qian Li
J. Cancer 2025; 16(8): 2434-2448. doi:10.7150/jca.99599
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A Comprehensive Analysis of the Role of DSN1 in Pan-Cancer Prognosis and Immunotherapy
Donggang Xu, Yue Zhang, Maoqia Shen, Xiaolong Cao
J. Cancer 2025; 16(8): 2449-2465. doi:10.7150/jca.111585
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High MIG-6 expression promotes tumor proliferation and metastasis of gastric cancer
Wenqiu Zhao, Tao Jin, Yun Liu, Shihe Shao, Feilun Cui
J. Cancer 2025; 16(8): 2466-2475. doi:10.7150/jca.98431
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Retinoic acid metabolism related gene CYP26B1 promotes tumor stemness and tumor microenvironment remodeling in bladder cancer
Jun Gu, Zhen-Duo Shi, Kun Pang, Lin Hao, Wei Wang, Cong-hui Han
J. Cancer 2025; 16(8): 2476-2491. doi:10.7150/jca.101406
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In vitro antioxidant, anticholinesterase, and antiproliferative activities of methanol extracts of Crateva religiosa bark
Md Sifat Hossain, Md Abdul Majed Patwary, Sharmin Akther Rupa, Mohsin Kazi, Ashok Kumar, Khalid M Alghamdi, Mohammed Mahbubul Matin, Md. Rezaur Rahman
J. Cancer 2025; 16(8): 2492-2502. doi:10.7150/jca.94492
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Hypoxia regulates glycolysis through the HIF-1α/BMAL1/ALDOC axis to reduce oxaliplatin sensitivity in colorectal cancer
Jialing Ran, Feifei Li, Lei Zhan, Yue Jin, Qian Dong, Xiaoyan Li, XiaoXi Li, Qian Fei, Jingdong Zhang
J. Cancer 2025; 16(8): 2503-2515. doi:10.7150/jca.108582
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Pyroptosis-Related Gene Signatures Enable Robustly Diagnosis, Prognosis and Immune Responses Prediction in Uterine Corpus Endometrial Carcinoma
Xuanming Chen, Xiangyu Jin, Jiafu Wang, Hanfei Li, Chuanfang Wu, Jinku Bao
J. Cancer 2025; 16(8): 2516-2536. doi:10.7150/jca.104826
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Development And Validation of An RNA Binding Protein-Associated Prognostic Model for Colon Adenocarcinoma
Xiajing Yu, Daixin Guo, Jie Gao, Jialing Hu, Wenyige Zhang, Qijun Yang, Jingyi Wang, Yingcheng He, Kaili Liao, Xiaozhong Wang
J. Cancer 2025; 16(8): 2537-2552. doi:10.7150/jca.103477
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Ursolic Acid induces ferroptosis by affecting redox balance and FADS2-mediated unsaturated fatty acid synthesis in Non-Small Cell Lung Cancer
Lanlan Yang, Yuan Fang, Yuli Wang, Yingbin Luo, Yanbin Pan, Jianchun Wu, Yan Li
J. Cancer 2025; 16(8): 2553-2566. doi:10.7150/jca.105863
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Theaflavin-3,3′-digallate triggers apoptosis in osteosarcoma cells via the caspase pathway
Yat-Yin Law, Yi-Hsien Hsieh, Yih-Shou Hsieh, Yi-Hsun Lee, Chia-Ling Tang, Chia-Yi Lee, Shun-Fa Yang, Shu-Chen Chu, Pei-Ni Chen
J. Cancer 2025; 16(8): 2567-2577. doi:10.7150/jca.111718
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Identification of Quercetin as a Natural MMP1 Inhibitor for Overcoming Cisplatin Resistance in Epithelial Ovarian Cancer
Shubo Wang, Ziming Zhao, Lili Yu, Jue Wang, Yue Ouyang, Hua Zhou, Weixing Shen, Qibiao Wu
J. Cancer 2025; 16(8): 2578-2594. doi:10.7150/jca.110517
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Resveratrol Induces Oxidative Stress and Downregulates GPX4 and xCT to Activate the Ferroptosis Pathway for Anti-Bladder Cancer Organoids
Xiang Chen, Jun-Lin Lu, Hong Li, Guang-Yao Liu, Ting-Ting Li, Kang-Hua Xiao, Hai-Shan Ye, Sheng Li, Xu Chen, Jia Liu
J. Cancer 2025; 16(8): 2613-2625. doi:10.7150/jca.109350
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Pan-cancer analysis identifies DBF4B as an immunologic and prognostic biomarker
Chongjiu Qin, Yu Chen, Haifei Qin, Xinlei Huang, Haixiang Xie, Kejian Yang, Junqi Liu, Xin Zhou, Xiwen Liao, Chuangye Han, Hao Su, Guohong Yan, Zuying Wan, Tao Peng, Guangzhi Zhu
J. Cancer 2025; 16(8): 2626-2648. doi:10.7150/jca.109134
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Omega-6/Omega-3 Ratio as a Protective Factor in Lung Cancer: A Mendelian Randomization Study on Polyunsaturated Fatty Acids and Lung Adenocarcinoma Risk
Cheng Wang, Ya Ding, Qikang Hu, Bin Wang, Shouzhi Xie, Zhi Yang, Zhe Zhang, Dexing Dai, An Xiong, Ruoman Sun, Yali Ling, Lei Qiu, Fenglei Yu, Zhongjian Xie, Muyun Peng
J. Cancer 2025; 16(8): 2649-2662. doi:10.7150/jca.112416
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Pretreatment Multi-sequence Contrast-Enhanced MRI to Predict Response to Immunotherapy in Unresectable Hepatocellular Carcinoma Using Transformer: A Multicenter Study
Jialin Chen, Juan Chen, Yamei Ye, Linbin Lu, Xinying Guo, Simiao Gao, Lifang Liu, Hongyi Yang, Chun Lin, Xiong Chen
J. Cancer 2025; 16(8): 2663-2672. doi:10.7150/jca.111026
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Prognostic Value of Des-Gamma-Carboxy Prothrombin in AFP-Negative Hepatocellular Carcinoma Patients Following Liver Resection: A Multicenter Study
Si-Yu Liu, Mu-Gen Dai, Wen-Feng Lu, Lei Liang, Jun-Wei Liu, Zhuo-Kai Li, Bin Ye
J. Cancer 2025; 16(8): 2680-2689. doi:10.7150/jca.112394
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Two-Sample Network Mendelian Randomization and Single-Cell Analysis Reveal the Causal Associations and Underlying Mechanisms Between Antihypertensive Drugs and Kidney Cancer
Ruiyi Deng, Mingrui Zou, Jianhui Qiu, Jiaheng Shang, Chaojian Yu, Peidong Tian, Yizhou Wang, Lin Cai, Jingcheng Zhou, Kan Gong
J. Cancer 2025; 16(8): 2690-2705. doi:10.7150/jca.110850
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Revealing Potential Therapeutic Targets in Gastric Cancer through Inflammation and Protein-Protein Interaction Hub Networks
Wei Wu, Guoliang Li, Lixin Chai, Yating Yin, Xin Xu, Chenlun Han, Hongyong Liu, Yi Cao, Yumiao Wang, Qunhao Guo, Wenxuan Chen, Peter Wang, Zhijian Pan
J. Cancer 2025; 16(8): 2720-2736. doi:10.7150/jca.112218
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Stanniocalcin-2 significantly promotes colorectal cancer progression by regulating cancer cell proliferation and invasion
Fang Li, Zihao Liu, Kaibin Huang, Shunkai Ding, Chang Zhu, Yuxiang Fu, Xiao Sun, Shipai Zhang, Rui Zhang, Zhipeng Jiang, Keli Zhong, Qijun Zheng
J. Cancer 2025; 16(8): 2737-2749. doi:10.7150/jca.101892
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TACE Empowers Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors in Unresectable HCC: A Multicenter Retrospective Study
Yu Lei, Yaowei Bai, Xiatong Bai, Jiacheng Liu, Bo Sun, Wenlong Wu, Xiaoling Zhi, Yang Su, Hongsen Zhang, Chuansheng Zheng
J. Cancer 2025; 16(8): 2750-2761. doi:10.7150/jca.112706
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Integrated machine learning based on cuproptosis and RNA methylation regulators to explore the molecular model of prostate cancer and provide novel insights to immunotherapy
Junchao Wu, Wentian Wu, Jiaxuan Qin, Ziqi Chen, Rongfang Zhong, Xunkai Zhu, Jialin Meng, Peng Guo, Song Fan
J. Cancer 2025; 16(8): 2762-2777. doi:10.7150/jca.112843
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Reviews
Development of Traditional Chinese Medicine in combination with EGFR Inhibitors against Cancer
Xiao Chen, Tiansheng Zheng, Bingjie Hao, Shumeng Lin, Liduo Yue, Lihong Fan
J. Cancer 2025; 16(8): 2595-2612. doi:10.7150/jca.109420
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Current status and future prospects of cancer-derived immunoglobulins in pancreatic cancer
Rui Ma, Fusheng Zhang, Yongsu Ma, Weikang Liu, Guangnian Liu, Yiran Chen, Jixin Zhang, Yinmo Yang, Xiaodong Tian
J. Cancer 2025; 16(8): 2673-2679. doi:10.7150/jca.109497
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Navigating the role of protein lactylation in prostate cancer and its implications for immunotherapy
Dongzhang Li, Kaifeng Wang, Guantao Lou, Wangjian Li, Quan Ma, Yu'e Liu, Yongliang Chen
J. Cancer 2025; 16(8): 2706-2719. doi:10.7150/jca.114137
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