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Volume 16 (7); 2025

Research Papers

Graphic abstract

A novel prognostic model to predict prognosis of patients with osteosarcoma based on clinical characteristics and blood biomarkers
Shulin Chen, Liru Tian, Chuan Li, Dongmei Zhong, Tingting Wang, Yuyu Chen, Taifeng Zhou, Xiaoming Yang, Zhiheng Liao, Caixia Xu
J. Cancer 2025; 16(7): 2075-2086. doi:10.7150/jca.105590
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Cholesterol metabolism-related genes predict immune infiltration and prognosis in gastric cancer patients
Wenxuan Liu, Li Liu, Tianrui Kuang, Wenhong Deng
J. Cancer 2025; 16(7): 2087-2102. doi:10.7150/jca.104389
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Identification and Characterization of Oxidative Stress and Endoplasmic Reticulum Stress-Related Genes in Esophageal Cancer
Xiaoxu Li, Juntao Lu, Yan Zhao, Wei Guo
J. Cancer 2025; 16(7): 2103-2123. doi:10.7150/jca.104376
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Vessel sign analysis paves the way to optimized CBCT application in interventional pulmonology: COMBINED algorithm as a one-stop-shop
Wolfgang Hohenforst-Schmidt, Ying Xu, Julia Greeven, Sander Langereis, Haidong Huang, Jian Liu, Xiaopeng Yao, Xiaping Shen, Yang Yang, Liangquan Wu, Paul Zarogoulidis, Stamatis Petousis, Chrysoula Margioula-Siarkou, Dimitris Petridis, Michael Steinheimer, Andreas Riedel, Noufal Aboobaker, Evaggelos Karamitrousis, Eleni-Isidora Perdikouri, Anastasios Vagionas, Thomas Vogl, Anil Sinha
J. Cancer 2025; 16(7): 2124-2144. doi:10.7150/jca.109996
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Identification and Validation of Prognostic Genes Related to Histone Lactylation Modification in Glioblastoma: An Integrated Analysis of Transcriptome and Single-cell RNA Sequencing
Wenfeng He, Ruihong Chen, Guangliang Chen, Lihan Zhang, Yuhang Qian, Jie Zhou, Jianhua Peng, Vincent Kam Wai Wong, Yong Jiang
J. Cancer 2025; 16(7): 2145-2166. doi:10.7150/jca.110646
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Pan-cancer analysis of DLAT reveals it as a prognostic Biomarker involved in immune infiltration of liver hepatocellular carcinoma
Haitao Xu, Yiqun Ma, Lishi Shao, Yao Fu, Bosheng Luo, Chunjuan Xia, Xiaoli Min
J. Cancer 2025; 16(7): 2167-2180. doi:10.7150/jca.102256
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SLC16A1 Inhibits Ferroptosis and Promotes the Progression of Head and Neck Squamous Cell Carcinoma
Huaiyuan Zong, Luyao Teng, Lifang Chen, Jianxin Qiu, Chunhui Tian
J. Cancer 2025; 16(7): 2184-2196. doi:10.7150/jca.110217
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Extracellular vesicles-miR-205-5p inhibits lymphatic metastasis in pancreatic cancer through diffusely downregulating VEGFA
Yuanyang Wang, Cheng Qin, Yutong Zhao, Bangbo Zhao, Zeru Li, Tianyu Li, Xiangyu Zhang, Weibin Wang
J. Cancer 2025; 16(7): 2197-2211. doi:10.7150/jca.110659
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Network Pharmacology and Experimental Validation-based Investigation of the Underlying Mechanism of Yi-Yi-Fu-Zi-Bai-Jiang-San of Nasopharyngeal Carcinoma
Zehua lin, Ting Huang, Baoai Han, Zezhang Tao, Xiong Chen
J. Cancer 2025; 16(7): 2212-2232. doi:10.7150/jca.109758
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RBM39 Functions as a Potential Oncogene Through the NF-κB Signaling Pathway in Colorectal Cancer Cells
YaTao Wang, XueSi Yang, ZhangQuan Yang, ZiRui Chen, HaiFeng Jiang, YiCong Wang, DongYan Shen, GuoQiang Su
J. Cancer 2025; 16(7): 2233-2249. doi:10.7150/jca.105120
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HPV Genotype, AGC Categories, and Age-Stratified Immediate Prevalence of Precancers and Cancers in Women with Atypical Glandular Cells with or without Concurrent Squamous Abnormal Cytology
Xin Zhou, Zicheng Huang, Wanrun Lin, Suming Huang, Huijuan Zhang, Wenxin Zheng, Yudong Wang, Feng Zhou
J. Cancer 2025; 16(7): 2250-2260. doi:10.7150/jca.105805
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circ_0046599 Promotes HCC Progression by Competing with miR-1322 to Enhance NT5DC2 Expression
Xiaobo Zhang, Suxin Li, Luhao Li, Dingyang Li, Huashan Zhao, Xiaole Gao, Xiaowei Dang
J. Cancer 2025; 16(7): 2275-2288. doi:10.7150/jca.103661
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Arachidonic acid promotes myeloid differentiation of splenic CD45- Ter119+ cells in myeloproliferative neoplasm
Linlin Zhang, Yi Yang, Xiao Yu, Guodong Li, Peihua Zhang, Xiaomin Ren, Siyu Luo, Lin Li, Gustave Munyurangabo, Yachun Jia, Lingqin Song, Aili He, Guangyao Kong
J. Cancer 2025; 16(7): 2289-2297. doi:10.7150/jca.110478
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Effects of Exercise Intensity and Time on Efficacy of Paclitaxel and Doxorubicin and Immune Microenvironment in the 4T1 Breast Cancer Model
Liang Zhou, Yonghong Yang, Xiang Luo, Xinling Gan, Chengqi He, Yong Xia, Siyi Zhu
J. Cancer 2025; 16(7): 2298-2311. doi:10.7150/jca.105352
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Clinicopathological and Molecular Characterization of Non-Endometrioid Endometrial Carcinoma
Danqing Zhu, Keyi Shi, Dongxiao Hu, Wanrun Lin, Xiaofei Zhang, Feng Zhou, Yang Li
J. Cancer 2025; 16(7): 2312-2320. doi:10.7150/jca.108685
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Construction of a Prognostic Model for Cervical Cancer Related to lncRNA Based on Differential Co-expression Network and Functional Study of Key Gene EGFR-AS1
Kailong Du, Qian Chen, Hui Fan, Yunlong Lei, Jian Zhang
J. Cancer 2025; 16(7): 2321-2338. doi:10.7150/jca.108429
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Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways
Xiaonan Yang, Zhimin Ding, Hongting Hua, Ruijia Gan, Dongdong Meng, Yan Zang, Han Xiao, Dong Wang, Wanjin Jiang, Dongyu Si, Xiang Wei, Mei Zhang, Huabing Zhang, Chaobing Gao
J. Cancer 2025; 16(7): 2339-2352. doi:10.7150/jca.92956
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Identification of the role of MED6 in the development and prognosis of lung adenocarcinoma based on multi-omics profiling
Changqing Yang, Ding Cheng, Shuo Wang, Baichuan Wang, Yingxi Li, Guixin Wang, Xingkai Wang, Cangchang Shi, Yao Tian, Keyun Zhu, Jing Feng
J. Cancer 2025; 16(7): 2362-2374. doi:10.7150/jca.110981
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Construction of a Prognostic Model based on CSC-related Genes in Patients with Colorectal Cancer
Zi-Yue Li, Ming-Feng Li, Ying-Ying He, Guan-Sheng Zheng, Jie-Rong Chen, Yun-Miao Guo, Qizhou Lian, Cai-Feng Yue
J. Cancer 2025; 16(7): 2375-2387. doi:10.7150/jca.108188
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MiR-371b-5p reduces osteosarcoma cell migration and proliferation to induce apoptosis by targeting FUT4
Qiang Xue, Ruicong Ma, YueYuan Chen, Xiaodi Yan, Jiajia Liu, Jianhua Xue, Yang Yang, Xianchen Liu
J. Cancer 2025; 16(7): 2388-2400. doi:10.7150/jca.103286
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Integration of multi-omics and single-cell transcriptome reveals mitochondrial outer membrane protein-2 (MTX-2) as a prognostic biomarker and characterizes ubiquinone metabolism in lung adenocarcinoma
Sachin Kumar, Chung-Che Wu, Fitria Sari Wulandari, Chung-Chieh Chiao, Ching-Chung Ko, Hung-Yun Lin, Juan Lorell Ngadio, Cathleen Rebecca, Do Thi Minh Xuan, Dahlak Daniel Solomon, Michael Michael, Lidya Kristiani, Jian-Ying Chuang, Ming-Cheng Tsai, Chih-Yang Wang
J. Cancer 2025; 16(7): 2401-2420. doi:10.7150/jca.106902
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Reviews

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Nano-strategies for Targeting Tumor-Associated Macrophages in Cancer immunotherapy
Qian Li, Jingwei Xu, Runjia Hua, Hanye Xu, Yongyou Wu, Xiaju Cheng
J. Cancer 2025; 16(7): 2261-2274. doi:10.7150/jca.108194
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SF3a1: A Novel Potential Tumor Biomarker or Therapeutic Target
Xueqian Shuai, Yaoqi Sun, Shupeng Liu, Zhongping Cheng
J. Cancer 2025; 16(7): 2353-2359. doi:10.7150/jca.103209
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Errata

Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells: Erratum
Xin Nie, Lingling Gao, Mingjun Zheng, Caixia Wang, Shuang Wang, Xiao Li, Yue Qi, Liancheng Zhu, Juanjuan Liu, Bei Lin
J. Cancer 2025; 16(7): 2181. doi:10.7150/jca.113036
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CCT8 promotes cell migration and tumor metastasis in lung adenocarcinomas: Erratum
Zhiqiang Wu, Liyuan Deng, Jin Tao, Yuhai Lu, Xiaofei Zeng, Weikun Jia, Hu Chen
J. Cancer 2025; 16(7): 2182-2183. doi:10.7150/jca.113359
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Co-delivery of Cyclopamine and Doxorubicin Mediated by Bovine Serum Albumin Nanoparticles Reverses Doxorubicin Resistance in Breast Cancer by Down-regulating P-glycoprotein Expression: Erratum
Yong-lin Lu, Ya-bin Ma, Chan Feng, Dong-lei Zhu, Jie Liu, Lv Chen, Shu-jing Liang, Chun-yan Dong
J. Cancer 2025; 16(7): 2360-2361. doi:10.7150/jca.113959
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