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Volume 11 (8); 2020

Research Papers

The combination of PKM2 overexpression and M2 macrophages infiltration confers a poor prognosis for PDAC patients
Hai Hu, Wenzhi Tu, Yungu Chen, Ming Zhu, Huan Jin, Ting Huang, Zhengzhi Zou, Qing Xia
J. Cancer 2020; 11(8): 2022-2031. doi:10.7150/jca.38981
[Abstract] [Full text] [PDF]

MRPS16 facilitates tumor progression via the PI3K/AKT/Snail signaling axis
Zhen Wang, Junjun Li, Xiaobing Long, Liwu Jiao, Minghui Zhou, Kang Wu
J. Cancer 2020; 11(8): 2032-2043. doi:10.7150/jca.39671
[Abstract] [Full text] [PDF]

Macrovascular Endothelial Cells Enhance the Motility of Liver Cancer Cells by Up-regulation of MMP-3, Activation of Integrin/FAK Signaling Pathway and Induction of Non-classical Epithelial-mesenchymal Transition
Song-Ming Ding, Ai-Li Lu, Jian-Fang Lu, Xu-Liang Chen, Muhammad Ibrahim Alhadi Edoo, Lin Zhou, Hai-Yang Xie, Shu-Sen Zheng, Qi-Yong Li
J. Cancer 2020; 11(8): 2044-2059. doi:10.7150/jca.38209
[Abstract] [Full text] [PDF]

Risk factors of acquired T790M mutation in patients with epidermal growth factor receptor-mutated advanced non-small cell lung cancer
Wen Ouyang, Jing Yu, Zhao Huang, Gang Chen, Yu Liu, Zhengkai Liao, Wei Zeng, Junhong Zhang, Conghua Xie
J. Cancer 2020; 11(8): 2060-2067. doi:10.7150/jca.37991
[Abstract] [Full text] [PDF]

Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression
Jincheng Zeng, Shasha Chen, Caihong Li, Ziyu Ye, Bihua Lin, Yanfang Liang, Bin Wang, Yan Ma, Xingxing Chai, Xin Zhang, Keyuan Zhou, Qunzhou Zhang, Haitao Zhang
J. Cancer 2020; 11(8): 2068-2079. doi:10.7150/jca.37932
[Abstract] [Full text] [PDF]

Nomograms for the Prediction of Survival for Patients with Pediatric Adrenal Cancer after Surgery
Junjiong Zheng, Jinhua Cai, Xiayao Diao, Jianqiu Kong, Xiong Chen, Hao Yu, Weibin Xie, Jian Huang, Tianxin Lin
J. Cancer 2020; 11(8): 2080-2090. doi:10.7150/jca.36861
[Abstract] [Full text] [PDF]

Cadherin 13 Inhibits Pancreatic Cancer Progression and Epithelial-mesenchymal Transition by Wnt/β-Catenin Signaling
Dengfei Xu, Hui Yuan, Zihong Meng, Chunmei Yang, Zefang Li, Mengge Li, Zhigang Zhang, Yu Gan, Hong Tu
J. Cancer 2020; 11(8): 2101-2112. doi:10.7150/jca.37762
[Abstract] [Full text] [PDF]

Circulating tumor cells as a new predictive and prognostic factor in patients with small cell lung cancer
Pei-Pei Wang, Si-Hong Liu, Cun-Te Chen, Lin Lv, Dan Li, Qiong-Yao Liu, Guo-Long Liu, Yong Wu
J. Cancer 2020; 11(8): 2113-2122. doi:10.7150/jca.35308
[Abstract] [Full text] [PDF]

Apigenin and Abivertinib, a novel BTK inhibitor synergize to inhibit diffuse large B-cell lymphoma in vivo and vitro
Shujuan Huang, Mengxia Yu, Nana Shi, Yile Zhou, Fengling Li, Xia Li, Xin Huang, Jie Jin
J. Cancer 2020; 11(8): 2123-2132. doi:10.7150/jca.34981
[Abstract] [Full text] [PDF]

Common genetic variants in pre-microRNAs are associated with cervical cancer susceptibility in southern Chinese women
Guange Chen, Mingyao Zhang, Jiawei Zhu, Feng Chen, Danyang Yu, Anqi Zhang, Jing He, Wenfeng Hua, Ping Duan
J. Cancer 2020; 11(8): 2133-2138. doi:10.7150/jca.39636
[Abstract] [Full text] [PDF]

A Combined four-mRNA Signature Associated with Lymphatic Metastasis for Prognosis of Colorectal Cancer
Xueping Li, Qiang Zhang, Lan Zhao, Longyang Jiang, Aoshuang Qi, Qian Wei, Xinyue Song, Lin Wang, Liwen Zhang, Yanyun Zhao, Xuemei Lv, Minjie Wei, Lin Zhao
J. Cancer 2020; 11(8): 2139-2149. doi:10.7150/jca.38796
[Abstract] [Full text] [PDF]

Bioinformatics analysis and identification of potential genes related to pathogenesis of cervical intraepithelial neoplasia
Xue Zhang, Jian Bai, Cheng Yuan, Long Long, Zhewen Zheng, Qingqing Wang, Fengxia Chen, Yunfeng Zhou
J. Cancer 2020; 11(8): 2150-2157. doi:10.7150/jca.38211
[Abstract] [Full text] [PDF]

B7-H3 promotes the cell cycle-mediated chemoresistance of colorectal cancer cells by regulating CDC25A
Yanchao Ma, Ruoqin Wang, Huimin Lu, Xiaomi Li, Guangbo Zhang, Fengqing Fu, Lei Cao, Shenghua Zhan, Zhenxin Wang, Zhongbin Deng, Tongguo Shi, Xueguang Zhang, Weichang Chen
J. Cancer 2020; 11(8): 2158-2170. doi:10.7150/jca.37255
[Abstract] [Full text] [PDF]

Prognostic Value of Albumin-to-Alkaline Phosphatase Ratio in Hepatocellular Carcinoma Patients Treated with Liver Transplantation
Hui Li, Li Wang, Liang Chen, Hui Zhao, Jianye Cai, Jia Yao, Jun Zheng, Yang Yang, Genshu Wang
J. Cancer 2020; 11(8): 2171-2180. doi:10.7150/jca.39615
[Abstract] [Full text] [PDF]

Visualization of gene therapy with a liver cancer-targeted adeno-associated virus 3 vector
Xusheng Liu, Hanling Huang, Yan Gao, Lumeng Zhou, Jianwei Yang, Xiaohui Li, Yang Li, Haiwen Zhao, Shanchun Su, Changbin Ke, Zhijun Pei
J. Cancer 2020; 11(8): 2192-2200. doi:10.7150/jca.39579
[Abstract] [Full text] [PDF]

Lnc-SNHG16/miR-128 axis modulates malignant phenotype through WNT/β-catenin pathway in cervical cancer cells
Wu Wu, Li Guo, Zhenlong Liang, Yuanbin Liu, Zhi Yao
J. Cancer 2020; 11(8): 2201-2212. doi:10.7150/jca.40319
[Abstract] [Full text] [PDF]

High Expression of Cancer-Derived Glycosylated Immunoglobulin G Predicts Poor Prognosis in Pancreatic Ductal Adenocarcinoma
Ming Cui, Lei You, Bang Zheng, Xinmei Huang, Qiaofei Liu, Jing Huang, Boju Pan, Xiaoyan Qiu, Quan Liao, Yupei Zhao
J. Cancer 2020; 11(8): 2213-2221. doi:10.7150/jca.39800
[Abstract] [Full text] [PDF]

The Role of MiR-5094 as a Proliferation Suppressor during Cellular Radiation Response via Downregulating STAT5b
Nan Ding, Junrui Hua, Jinpeng He, Dong Lu, Wenjun Wei, Yanan Zhang, Heng Zhou, Liying Zhang, Yongqi Liu, Guangming Zhou, Jufang Wang
J. Cancer 2020; 11(8): 2222-2233. doi:10.7150/jca.39679
[Abstract] [Full text] [PDF]

BCR-ABL1 transcript decline ratio combined BCR-ABL1IS as a precise predictor for imatinib response and outcome in the patients with chronic myeloid leukemia
Zhimei Cai, Xiting Jia, Jie Zi, Huihui Song, Shujun Wang, Mary McGrath, Lidong Zhao, Chunhua Song, Zheng Ge
J. Cancer 2020; 11(8): 2234-2240. doi:10.7150/jca.38752
[Abstract] [Full text] [PDF]

Therapeutic Rationale to Target Highly Expressed Aurora kinase A Conferring Poor Prognosis in Cholangiocarcinoma
Xiwei Ding, Tianlu Huang, Chunyan Peng, Keun Soo Ahn, Jesper B Andersen, Monika Lewinska, Yu Cao, Guifang Xu, Gang Chen, Bo Kong, Helmut Friess, Shanshan Shen, Lewis R Roberts, Lei Wang, Xiaoping Zou
J. Cancer 2020; 11(8): 2241-2251. doi:10.7150/jca.31989
[Abstract] [Full text] [PDF]

The Correlation between EGFR Mutation Status and DNA Content of Lung Adenocarcinoma Cells in Pleural Effusion
Yun Du, Xiao Guo, Rui Wang, Yang Ma, Yan Zhang, Ying Liu, Lvli Dong, Juan Wu, Xiaokun Ji, Heng Wang
J. Cancer 2020; 11(8): 2265-2272. doi:10.7150/jca.38615
[Abstract] [Full text] [PDF]

InvivoPen: A novel plasma source for in vivo cancer treatment
Xin Zhou, Dongyan Cai, Shaoqing Xiao, Meng Ning, Renwu Zhou, Shuo Zhang, Xiao Chen, Kostya Ostrikov, Xiaofeng Dai
J. Cancer 2020; 11(8): 2273-2282. doi:10.7150/jca.38613
[Abstract] [Full text] [PDF]

Preoperative evaluation of residual tumor in patients with endometrial carcinoma by using 18F-FDG PET/CT
Chunhua Wu, Ruohua Chen, Xiang Zhou, Qian Xia, Jianjun Liu
J. Cancer 2020; 11(8): 2283-2288. doi:10.7150/jca.39423
[Abstract] [Full text] [PDF]

FAM115C could be a novel tumor suppressor associated with prolonged survival in pancreatic cancer patients
Kiyoshi Saeki, Hideya Onishi, Satoko Koga, Shu Ichimiya, Kazunori Nakayama, Yasuhiro Oyama, Makoto Kawamoto, Kukiko Sakihama, Takeo Yamamoto, Ryota Matsuda, Yoshihiro Miyasaka, Masafumi Nakamura, Yoshinao Oda
J. Cancer 2020; 11(8): 2289-2302. doi:10.7150/jca.38399
[Abstract] [Full text] [PDF]

Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells
Bolin Yang, Huiru Bai, Yunli Sa, Ping Zhu, Ping Liu
J. Cancer 2020; 11(8): 2303-2317. doi:10.7150/jca.37242
[Abstract] [Full text] [PDF]

Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms
Xiaojun Xu, Kazufumi Honda, Nami Miura, Shutaro Hori, Solange Le Blanc, Frank Bergmann, Matthias M. Gaida, Michael Volkmar, Simon Schimmack, Thilo Hackert, Oliver Strobel, Klaus Felix
J. Cancer 2020; 11(8): 2318-2328. doi:10.7150/jca.37503
[Abstract] [Full text] [PDF]

Precise prediction of the radiation pneumonitis in lung cancer: an explorative preliminary mathematical model using genotype information
Lehui Du, Na Ma, Xiangkun Dai, Wei Yu, Xiang Huang, Shouping Xu, Fang Liu, Qiduo He, Yanli Liu, Qian Wang, Xiangtao Liu, Hui Zheng, Baolin Qu
J. Cancer 2020; 11(8): 2329-2338. doi:10.7150/jca.37708
[Abstract] [Full text] [PDF]

Weighted gene co-expression network analysis identified MYL9 and CNN1 are associated with recurrence in colorectal cancer
Xiao Qiu, Shen-Hong Cheng, Fei Xu, Jin-Wen Yin, Li-Yang Wang, Xin-You Zhang
J. Cancer 2020; 11(8): 2348-2359. doi:10.7150/jca.39723
[Abstract] [Full text] [PDF]

Curcumin Enhances Radiosensitization of Nasopharyngeal Carcinoma via Mediating Regulation of Tumor Stem-like Cells by a CircRNA Network
Daoqi Zhu, Meng Shao, Jiabin Yang, Miao Fang, Shiya Liu, Dandan Lou, Ruijiao Gao, Ying Liu, Aiwu Li, Ying Lv, Zhixian Mo, Qin Fan
J. Cancer 2020; 11(8): 2360-2370. doi:10.7150/jca.39511
[Abstract] [Full text] [PDF]

Reviews

FGF/FGFR signaling pathway involved resistance in various cancer types
Yangyang Zhou, Chengyu Wu, Guangrong Lu, Zijing Hu, Qiuxiang Chen, Xiaojing Du
J. Cancer 2020; 11(8): 2000-2007. doi:10.7150/jca.40531
[Abstract] [Full text] [PDF]

Glypican-3: A New Target for Diagnosis and Treatment of Hepatocellular Carcinoma
Meng Guo, Hailing Zhang, Jianming Zheng, Yangfang Liu
J. Cancer 2020; 11(8): 2008-2021. doi:10.7150/jca.39972
[Abstract] [Full text] [PDF]

Epstein barr virus encodes miRNAs to assist host immune escape
Weiming Li, Cong He, Jiayi Wu, Dazhi Yang, Weihong Yi
J. Cancer 2020; 11(8): 2091-2100. doi:10.7150/jca.42498
[Abstract] [Full text] [PDF]

Association of microRNA biosynthesis genes XPO5 and RAN polymorphisms with cancer susceptibility: Bayesian hierarchical meta-analysis
Yi Shao, Yi Shen, Lei Zhao, Xudong Guo, Chen Niu, Fen Liu
J. Cancer 2020; 11(8): 2181-2191. doi:10.7150/jca.37150
[Abstract] [Full text] [PDF]

The role of YWHAZ in cancer: A maze of opportunities and challenges
Yun Gan, Feng Ye, Xing-Xing He
J. Cancer 2020; 11(8): 2252-2264. doi:10.7150/jca.41316
[Abstract] [Full text] [PDF]

Diffusion Kurtosis Imaging for Assessing the Therapeutic Response of Transcatheter Arterial Chemoembolization in Hepatocellular Carcinoma
Zhen-Guo Yuan, Zong-Ying Wang, Meng-Ying Xia, Feng-Zhi Li, Yao Li, Zhen Shen, Xi-Zhen Wang
J. Cancer 2020; 11(8): 2339-2347. doi:10.7150/jca.32491
[Abstract] [Full text] [PDF]