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Volume 12 (16); 2021

Hypothesis

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Hypothesis: Sam68 and Pygo2 mediate cell type-specific effects of the modulation of CBP-Wnt and p300-Wnt activities in Colorectal Cancer Cells
Michael Bordonaro
J. Cancer 2021; 12(16): 5046-5052. doi:10.7150/jca.59726
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Papers

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A nomogram to predict the prognosis of patients with unresected rectal adenocarcinoma undergoing chemoradiotherapy: a population-based study
Lin-Lin Liu, Jun-Die Sun, Zuo-Lin Xiang
J. Cancer 2021; 12(16): 4745-4761. doi:10.7150/jca.61642
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prognostic and immunological role of CD36: A pan-cancer analysis
Yong-Jian Chen, Wei-Xin Liao, Shao-Zhuo Huang, Yun-Fang Yu, Jing-Yun Wen, Jie Chen, Da-Gui Lin, Xiang-Yuan Wu, Nan Jiang, Xing Li
J. Cancer 2021; 12(16): 4762-4773. doi:10.7150/jca.50502
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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EIF5A expression and its role as a potential diagnostic biomarker in hepatocellular carcinoma
Linjing Li, Xin Li, Qingyan Zhang, Tao Ye, Shuli Zou, Jing Yan
J. Cancer 2021; 12(16): 4774-4779. doi:10.7150/jca.58168
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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ALDH3A1 driving tumor metastasis is mediated by p53/BAG1 in lung adenocarcinoma
Feifei Fan, Ruxue Yin, Liuya Wang, Shunxin Zhao, Dan Lv, Kangli Yang, Shen Geng, Ningning Yang, Xiaohong Zhang, Hongmin Wang
J. Cancer 2021; 12(16): 4780-4790. doi:10.7150/jca.58250
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Upregulating KTN1 promotes Hepatocellular Carcinoma progression
Jian Pan, Nai-Xia Chao, Yao-Yao Zhang, Tian-Ming Huang, Cheng-Xiao Chen, Qiu-Hong Qin, Jin-Hong Guo, Rong-Shi Huang, Guo-Rong Luo
J. Cancer 2021; 12(16): 4791-4809. doi:10.7150/jca.55570
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prognostic significance of miR-203 and ZEB1 expression in early-stage hepatocellular carcinoma
Hongyuan Chen, Meng Kong, Ying Chen, Yugang Jiang, Mingxin Wen, Xinke Zhang
J. Cancer 2021; 12(16): 4810-4818. doi:10.7150/jca.57819
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Upregulation of V-ATPase by STAT3 Activation Promotes Anoikis Resistance and Tumor Metastasis
Funmilayo O. Adeshakin, Adeleye O. Adeshakin, Zhao Liu, Xiaoxu Lu, Jian Cheng, Pengchao Zhang, Dehong Yan, Guizhong Zhang, Xiaochun Wan
J. Cancer 2021; 12(16): 4819-4829. doi:10.7150/jca.58670
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation
Qiqi Zhang, Qing Liu, Shutao Zheng, Tao Liu, Lifei Yang, Xiujuan Han, Xiaomei Lu
J. Cancer 2021; 12(16): 4830-4840. doi:10.7150/jca.58494
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MRPS17 promotes invasion and metastasis through PI3K/AKT signal pathway and could be potential prognostic marker for gastric cancer
Wenjie Zhou, Jun Ouyang, Junqing Li, Fangjie Liu, Tailai An, Lvjia Cheng, Zi Chong Kuo, Changhua Zhang, Yulong He
J. Cancer 2021; 12(16): 4849-4861. doi:10.7150/jca.55719
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Exosomal IDH1 increases the resistance of colorectal cancer cells to 5-Fluorouracil
Hao Yang, Sha Xie, Beibei Liang, Qiqi Tang, Huanchen Liu, Dongliang Wang, Gang Huang
J. Cancer 2021; 12(16): 4862-4872. doi:10.7150/jca.58846
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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TRA2A Binds With LncRNA MALAT1 To Promote Esophageal Cancer Progression By Regulating EZH2/β-catenin Pathway
Xing Zhao, Qiuyang Chen, Yujie Cai, Danze Chen, Mingrong Bei, Hongyan Dong, Jianzhen Xu
J. Cancer 2021; 12(16): 4883-4890. doi:10.7150/jca.55661
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Long Noncoding RNA LIT3527 Knockdown induces Apoptosis and Autophagy through inhibiting mTOR pathway in Gastric Cancer Cells
Boya Wang, Yujie Deng, Juan Jin, Yan Wu, Lirong Shen
J. Cancer 2021; 12(16): 4901-4911. doi:10.7150/jca.58185
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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A clinical prediction model identifies a subgroup with inferior survival within intermediate risk acute myeloid leukemia
Xiaoxia Hu, Bianhong Wang, Qi Chen, Aijie Huang, Weijia Fu, Lixia Liu, Ying Zhang, Gusheng Tang, Hui Cheng, Xiong Ni, Lei Gao, Jie Chen, Li Chen, Weiping Zhang, Jianmin Yang, Shanbo Cao, Li Yu, Jianmin Wang
J. Cancer 2021; 12(16): 4912-4923. doi:10.7150/jca.57231
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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circALPL Sponges miR-127 to Promote Gastric Cancer Progression by Enhancing MTDH Expression
Peng Wu, Dongmei Ye, Jiaoyan Li, Fei Yan, Xin Jin, Zhiwei Zhang, Zhenfa Li
J. Cancer 2021; 12(16): 4924-4932. doi:10.7150/jca.49942
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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MicroRNA-124-3p inhibited progression of nasopharyngeal carcinoma by interaction with PCDH8 and the inactivation of PI3K/AKT/mTOR pathway
Jiacai Ye, Quanxing Liao, Xiaohui Zeng, Chang Liu, Yan Ding, Xuefeng Liu, Lisi Zeng, Tianpei Guan, Yawei Yuan
J. Cancer 2021; 12(16): 4933-4944. doi:10.7150/jca.57152
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway
Xinchun Xu, Xiaofeng Xuan, Jieru Zhang, Hui Xu, Xiaomei Yang, Ling Zhang, Yuanjie Zhao, Hong Xu, Dawei Li
J. Cancer 2021; 12(16): 4945-4957. doi:10.7150/jca.53613
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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LncRNA SNHG14 promotes cell proliferation and invasion in colorectal cancer through modulating miR-519b-3p/DDX5 axis
Xiaoyuan Wang, Peng Yang, Dongsheng Zhang, Ming Lu, Chi Zhang, Yueming Sun
J. Cancer 2021; 12(16): 4958-4970. doi:10.7150/jca.55495
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Integrating 13 Microarrays to Construct a 6 RNA-binding proteins Prognostic Signature for Gastric Cancer patients
Liqiang Zhou, Qi Zhou, You Wu, Lin Xin
J. Cancer 2021; 12(16): 4971-4984. doi:10.7150/jca.57225
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Reduced survival of young patients under 55 years with metastatic prostate cancer: a population-based study
Pan Song, Zhufeng Peng, Mengxuan Shu, Jiaxiang Wang, Peiwen Liu, Xiaoyu Di, Luchen Yang, Zhenghuan Liu, Jing Zhou, Qiang Dong
J. Cancer 2021; 12(16): 4985-4992. doi:10.7150/jca.58144
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells
Jesús S Aguilar Díaz de león, Honor L Glenn, Mark Knappenberger, Chad R Borges
J. Cancer 2021; 12(16): 4993-5004. doi:10.7150/jca.55526
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Plasma exosomal caveolin-1 predicts Poor Prognosis in Ovarian Cancer
Lijuan Yang, Haohao Wu, Yan Zhu, Xiaoping Chen, Youguo Chen
J. Cancer 2021; 12(16): 5005-5012. doi:10.7150/jca.58762
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells
Naiyi Zou, Xueyuan Zhang, Shuguang Li, Youmei Li, Yan Zhao, Xingxiao Yang, Shuchai Zhu
J. Cancer 2021; 12(16): 5013-5024. doi:10.7150/jca.58023
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Prognostic Significance of the Preoperative Albumin/Fibrinogen Ratio in Patients with Esophageal Squamous Cell Carcinoma after Surgical Resection
Hongdian Zhang, Peng Ren, Mingquan Ma, Xiaolei Zhu, Kai Zhu, Wanyi Xiao, Lei Gong, Peng Tang, Zhentao Yu
J. Cancer 2021; 12(16): 5025-5034. doi:10.7150/jca.58022
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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miR-30a/SOX4 Double Negative Feedback Loop is modulated by Disulfiram and regulates EMT and Stem Cell-like properties in Breast Cancer
Zijian Liu, Mi Mi, Xin Zheng, Caijiao Zhang, Fang Zhu, Tao Liu, Gang Wu, Liling Zhang
J. Cancer 2021; 12(16): 5053-5065. doi:10.7150/jca.57752
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Evaluation of the value of Preoperative Sialic Acid Levels in Diagnosis and Localization of Urothelial Tumors
Dongshan Chen, Dawei Li, Zhanwu Cui, Cong Zhang, Zhao Zhang, Lei Yan
J. Cancer 2021; 12(16): 5066-5075. doi:10.7150/jca.45648
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reviews

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Tumor-related Microbiome in the Breast Microenvironment and Breast Cancer
Na Wang, Tao Sun, Junnan Xu
J. Cancer 2021; 12(16): 4841-4848. doi:10.7150/jca.58986
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Potential impact and mechanism of Long Non-coding RNAs on cancer and associated T cells
Wenxiu Chen, Shuna Liu, Fang Wang
J. Cancer 2021; 12(16): 4873-4882. doi:10.7150/jca.58859
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Chlamydia Trachomatis Infection: Their potential implication in the Etiology of Cervical Cancer
Xingju Yang, Anam Siddique, Abdul Arif Khan, Qian Wang, Abdul Malik, Arif Tasleem Jan, Hassan Ahmed Rudayni, Anis Ahmad Chaudhary, Shahanavaj Khan
J. Cancer 2021; 12(16): 4891-4900. doi:10.7150/jca.58582
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Emerging Diagnostic Potential of Tumor-derived Exosomes
Ruhua Luo, Mengmeng Liu, Qian Yang, Huijuan Cheng, Huimin Yang, Minhui Li, Xue Bai, Yue Wang, Honghua Zhang, Shuling Wang, Tian Xie, Qingchang Tian
J. Cancer 2021; 12(16): 5035-5045. doi:10.7150/jca.59391
[Abstract] [Full text] [PDF] [PubMed] [PMC]