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Volume 12 (1); 2021

Research Papers

Specific MiRNAs in naïve T cells associated with Hepatitis C Virus-induced Hepatocellular Carcinoma
Peng Yan, Pengfei Pang, Xiaojun Hu, Ani Wang, Huitao Zhang, Yingdong Ma, Ke Zhang, Yaochao Ye, Bin Zhou, Junjie Mao
J. Cancer 2021; 12(1): 1-9. doi:10.7150/jca.49594
[Abstract] [Full text] [PDF]

The role of chemotherapy in patients with T1bN0M0 triple-negative breast cancer: a real-world competing risk analysis
Tian Lan, Yunyan Lu, Hua Luo, Ouou Yang, Junling He, Haibin Xu, Zujian Hu
J. Cancer 2021; 12(1): 10-17. doi:10.7150/jca.52540
[Abstract] [Full text] [PDF]

Clinical value of docetaxel plus cisplatin (TP) induction chemotherapy followed by TP concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma
Hao-Yun Tao, Ze-Jiang Zhan, Wen-Ze Qiu, Kai Liao, Ya-Wei Yuan, Tai-Ze Yuan, Rong-Hui Zheng
J. Cancer 2021; 12(1): 18-27. doi:10.7150/jca.49944
[Abstract] [Full text] [PDF]

Downregulation of CDH11 Promotes Metastasis and Resistance to Paclitaxel in Gastric Cancer Cells
Zhongyin Yang, Chao Yan, Zhenjia Yu, Changyu He, Jianfang Li, Chen Li, Min Yan, Bingya Liu, Yingli Wu, Zhenggang Zhu
J. Cancer 2021; 12(1): 65-75. doi:10.7150/jca.48193
[Abstract] [Full text] [PDF]

Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway
Chang Bao, Tao Liu, Lingbo Qian, Chi Xiao, Xinru Zhou, Heng Ai, Jue Wang, Weimin Fan, Jie Pan
J. Cancer 2021; 12(1): 76-88. doi:10.7150/jca.47553
[Abstract] [Full text] [PDF]

Inhibition of SPATS2 Suppresses Proliferation and Invasion of Hepatocellular Carcinoma Cells through TRIM44-STAT3 Signaling Pathway
Lirong Chen, Chenhe Yi, Wenshuai Li, Yujen Tseng, Jun Zhang, Jie Liu
J. Cancer 2021; 12(1): 89-98. doi:10.7150/jca.47526
[Abstract] [Full text] [PDF]

GINS2 attenuates the development of lung cancer by inhibiting the STAT signaling pathway
Dianmin Sun, Yuanyuan Zong, Jinling Cheng, Zhenxiang Li, Ligang Xing, Jinming Yu
J. Cancer 2021; 12(1): 99-110. doi:10.7150/jca.46744
[Abstract] [Full text] [PDF]

Lower dietary mineral intake is significantly associated with cervical cancer risk in a population-based cross-sectional study
Zhe Wang, Wenhao Wang, Aimin Yang, Weihong Zhao, Jing Yang, Zhilian Wang, Wei Wang, Xiaoqiang Su, Jintao Wang, Jinghui Song, Li Li, Weiguo Lv, Dongyan Li, Huiqiang Liu, Chen Wang, Min Hao
J. Cancer 2021; 12(1): 111-123. doi:10.7150/jca.39806
[Abstract] [Full text] [PDF]

Screening Study on the Anti-Angiogenic Effects of Traditional Chinese Medicine - Part II: Wild Chrysanthemum
Xiang Tu, He Bin Wang, Qun Huang, Yi Cai, Yuan Ping Deng, Zhe Yong, Quan Hu, Jian Feng, James B. Jordan, Sen Zhong
J. Cancer 2021; 12(1): 124-133. doi:10.7150/jca.52971
[Abstract] [Full text] [PDF]

U three protein 14a (UTP14A) promotes tumour proliferation and metastasis via the PERK/eIF2a/GRP78 signalling pathway in oesophageal squamous cell carcinoma
Kun-Kun Li, Cheng-Yi Mao, Qiang Ma, Tao Bao, Ying-Jian Wang, Wei Guo, Xiao-Long Zhao
J. Cancer 2021; 12(1): 134-140. doi:10.7150/jca.44649
[Abstract] [Full text] [PDF]

Increased Reactive Oxygen Species and Distinct Oxidative Damage in Resveratrol-suppressed Glioblastoma Cells
Bin Jia, Xu Zheng, Mo-Li Wu, Xiao-Ting Tian, Xue Song, Yan-Na Liu, Pei-Nan Li, Jia Liu
J. Cancer 2021; 12(1): 141-149. doi:10.7150/jca.45489
[Abstract] [Full text] [PDF]

ALKAL1 gene silencing prevents colorectal cancer progression via suppressing Sonic Hedgehog (SHH) signaling pathway
Shasha Chen, Bin Wang, Xuekun Fu, Yanfang Liang, Xingxing Chai, Ziyu Ye, Ronggang Li, Yaoming He, Gang Kong, Jiachun Lian, Xiangyong Li, Ting Chen, Xin Zhang, Xianxiu Qiu, Xudong Tang, Keyuan Zhou, Bihua Lin, Jincheng Zeng
J. Cancer 2021; 12(1): 150-162. doi:10.7150/jca.46447
[Abstract] [Full text] [PDF]

Gemcitabine, oxaliplatin and dexamethasone (GemDOx) as salvage therapy for relapsed or refractory diffuse large B-cell lymphoma and peripheral T-cell lymphoma
Qiu-Dan Shen, Li Wang, Hua-Yuan Zhu, Jin-Hua Liang, Yi Xia, Jia-Zhu Wu, Lei Fan, Jian-Yong Li, Wei Xu
J. Cancer 2021; 12(1): 163-169. doi:10.7150/jca.47031
[Abstract] [Full text] [PDF]

Distinct Impacts of Pre-Operative Antiviral Treatment on Post-Operative Outcomes of HBV-related Hepatocellular Carcinoma: A Landmark Analysis
Jun Fu, Zongren Ding, Qinjunjie Chen, Kongying Lin, Hongzhi Liu, Yuzhen Gao, Yongyi Zeng, Haitao Li, Feng Shen, Jingfeng Liu
J. Cancer 2021; 12(1): 170-180. doi:10.7150/jca.47125
[Abstract] [Full text] [PDF]

Loss of LIMCH1 predicts poor prognosis in patients with surgically resected Lung Adenocarcinoma: A study based on Immunohistochemical Analysis and Bioinformatics
He Cao, Jing Zhao, Zhen Chen, Wenjia Sun, Kexin Ruan, Jianya Zhou, Jianying Zhou
J. Cancer 2021; 12(1): 181-189. doi:10.7150/jca.47883
[Abstract] [Full text] [PDF]

A Noninvasive Assessment of Tumor Proliferation in Lung cancer Patients using Intravoxel Incoherent Motion Magnetic Resonance Imaging
Yu Zheng, Wenjun Huang, Xuelin Zhang, Chen Lu, Caixia Fu, Shihong Li, Guangwu Lin
J. Cancer 2021; 12(1): 190-197. doi:10.7150/jca.48589
[Abstract] [Full text] [PDF]

Emerging roles of MiR-133a in human cancers
Yu-Ting Hua, Wen-Xiu Xu, Hui Li, Min Xia
J. Cancer 2021; 12(1): 198-206. doi:10.7150/jca.48769
[Abstract] [Full text] [PDF]

Berberine inhibits the Warburg effect through TET3/miR-145/HK2 pathways in ovarian cancer cells
Jie Li, Yuliang Zou, Meili Pei, Yun Zhang, Yu Jiang
J. Cancer 2021; 12(1): 207-216. doi:10.7150/jca.48896
[Abstract] [Full text] [PDF]

LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma
Longrong Wang, Kai Yan, Xigan He, Hongxu Zhu, Jia Song, Shiqing Chen, Shangli Cai, Yiming Zhao, Lu Wang
J. Cancer 2021; 12(1): 217-223. doi:10.7150/jca.48983
[Abstract] [Full text] [PDF]

Down-regulation of ACACA suppresses the malignant progression of Prostate Cancer through inhibiting mitochondrial potential
Hui Zhang, Shaoyou Liu, Zhouda Cai, Weimin Dong, Jianheng Ye, Zhiduan Cai, Zhaodong Han, Yuxiang Liang, Yangjia Zhuo, Yong Luo, Xuejin Zhu, Yulin Deng, Yixun Zhang, Ren Liu, Yuanfa Feng, Jiarun Lai, Rui Zhou, Huijing Tan, Weide Zhong
J. Cancer 2021; 12(1): 232-243. doi:10.7150/jca.49560
[Abstract] [Full text] [PDF]

Synthesis and evaluation of 68Ga-labeled dimeric cNGR peptide for PET imaging of CD13 expression with ovarian cancer xenograft
Yi Yang, Jun Zhang, Huifeng Zou, Yang Shen, Shengming Deng, Yiwei Wu
J. Cancer 2021; 12(1): 244-252. doi:10.7150/jca.49628
[Abstract] [Full text] [PDF]

NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway
Jun-fu Wang, Kun Zhao, Ye-yang Chen, Yue Qiu, Jin-hui Zhu, Bo-pei Li, Zheng Wang, Jun-qiang Chen
J. Cancer 2021; 12(1): 253-263. doi:10.7150/jca.49709
[Abstract] [Full text] [PDF]

The Association of Polymorphisms in Base Excision Repair Genes with Ovarian Cancer Susceptibility in Chinese Women: A Two-Center Case-Control Study
Mingyao Zhang, Zhiguang Zhao, Sailing Chen, Zongwen Liang, Jiawei Zhu, Manman Zhao, Chaoyi Xu, Jing He, Ping Duan, Anqi Zhang
J. Cancer 2021; 12(1): 264-269. doi:10.7150/jca.49925
[Abstract] [Full text] [PDF]

Tephrosin induces apoptosis of human pancreatic cancer cells through the generation of reactive oxygen species
Jie Du, Fan Jiang, Shen-Sheng Xu, Zi-Feng Huang, Li‐Li Chen, Li Li
J. Cancer 2021; 12(1): 270-280. doi:10.7150/jca.50360
[Abstract] [Full text] [PDF]

HnRNP-F promotes the proliferation of bladder cancer cells mediated by PI3K/AKT/FOXO1
Fei Li, Weiwei Xie, Yunze Fang, Kunfeng Xie, Wendong Liu, Lina Hou, Wanlong Tan
J. Cancer 2021; 12(1): 281-291. doi:10.7150/jca.50490
[Abstract] [Full text] [PDF]

Risk-predicted dual nomograms consisting of clinical and ultrasound factors for downgrading BI-RADS category 4a breast lesions - A multiple centre study
Zihan Niu, Jia-Wei Tian, Hai-Tao Ran, Wei-Dong Ren, Cai Chang, Jian-Jun Yuan, Chun-Song Kang, You-Bin Deng, Hui Wang, Bao-Ming Luo, Sheng-Lan Guo, Qi Zhou, En-Sheng Xue, Wei-Wei Zhan, Qing Zhou, Jie Li, Ping Zhou, Chun-Quan Zhang, Man Chen, Ying Gu, Jin-Feng Xu, Wu Chen, Yu-Hong Zhang, Hong-Qiao Wang, Jian-Chu Li, Hong-Yan Wang, Yu-Xin Jiang
J. Cancer 2021; 12(1): 292-304. doi:10.7150/jca.51302
[Abstract] [Full text] [PDF]

Reviews

The Essential Factors of Establishing Patient-derived Tumor Model
Chuanzhi Chen, Wu Lin, Yingying Huang, Xiangliu Chen, Haohao Wang, Lisong Teng
J. Cancer 2021; 12(1): 28-37. doi:10.7150/jca.51749
[Abstract] [Full text] [PDF]

Current Ovarian Cancer Maintenance Strategies and Promising New Developments
Vinaya Gogineni, Susan Morand, Hannah Staats, Rachel Royfman, Monika Devanaboyina, Katelyn Einloth, Danielle Dever, Laura Stanbery, Phylicia Aaron, Luisa Manning, Adam Walter, Gerald Edelman, Lance Dworkin, John Nemunaitis
J. Cancer 2021; 12(1): 38-53. doi:10.7150/jca.49406
[Abstract] [Full text] [PDF]

Tumor-associated macrophages: role in tumorigenesis and immunotherapy implications
Shunyao Zhu, Ziyi Luo, Xixi Li, Xi Han, Senlin Shi, Ting Zhang
J. Cancer 2021; 12(1): 54-64. doi:10.7150/jca.49692
[Abstract] [Full text] [PDF]

The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker
Xuewen Tan, Haifeng Jiang, Yilong Fang, Dafei Han, Yawei Guo, Xinming Wang, Xun Gong, Wenming Hong, Jiajie Tu, Wei Wei
J. Cancer 2021; 12(1): 224-231. doi:10.7150/jca.49203
[Abstract] [Full text] [PDF]