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Volume 11 (6); 2020

Research Papers

p62 Suppressed VK3-induced Oxidative Damage Through Keap1/Nrf2 Pathway In Human Ovarian Cancer Cells
Mei-hui Xia, Xiao-yu Yan, Lei Zhou, Long Xu, Li-chao Zhang, Hao-wei Yi, Jing Su
J. Cancer 2020; 11(6): 1299-1307. doi:10.7150/jca.34423
[Abstract] [Full text] [PDF]

Creating nanocrystallized chemotherapy: the differences in pressurized aerosol chemotherapy (PAC) via intracavitary (IAG) and extracavitary aerosol generation (EAG) regarding particle generation, morphology and structure
Tanja Khosrawipour, Justyna Schubert, Joanna Kulas, Pawel Migdal, Mohamed Arafkas, Jacek Bania, Veria Khosrawipour
J. Cancer 2020; 11(6): 1308-1314. doi:10.7150/jca.39097
[Abstract] [Full text] [PDF]

Serum miR-1290 and miR-1246 as Potential Diagnostic Biomarkers of Human Pancreatic Cancer
Jia Wei, Lu Yang, Yi-ning Wu, Jian Xu
J. Cancer 2020; 11(6): 1325-1333. doi:10.7150/jca.38048
[Abstract] [Full text] [PDF]

Gustave Roussy Immune Score (GRIm-Score) is a prognostic marker in patients with resectable esophageal squamous cell carcinoma
Ji-Feng Feng, Liang Wang, Xun Yang, Sheng Chen
J. Cancer 2020; 11(6): 1334-1340. doi:10.7150/jca.37898
[Abstract] [Full text] [PDF]

Outcomes after Treatment of Metaplastic Versus Other Breast Cancer Subtypes
Amy C. Moreno, Yan Heather Lin, Isabelle Bedrosian, Yu Shen, Gildy V. Babiera, Simona F. Shaitelman
J. Cancer 2020; 11(6): 1341-1350. doi:10.7150/jca.40817
[Abstract] [Full text] [PDF]

High level of RNF187 contributes to the progression and drug resistance of osteosarcoma
Wen-Bing Wan, Kai Wu, Kun Peng, Zhi-Qiang Qiu, Zhi-Bin Duan, Xiang Chen, Ze-Min Xu, Ke Cheng, Jiang-Ming-Hao Zhao, Qing-Ming Shi
J. Cancer 2020; 11(6): 1351-1358. doi:10.7150/jca.33488
[Abstract] [Full text] [PDF]

The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1α
Fei Shi, Di Wei, Zheng Zhu, Fei Yan, Fuli Wang, Keke Zhang, Xi'an Li, Yu Zheng, Jiarui Yuan, Zifan Lu, Jianlin Yuan
J. Cancer 2020; 11(6): 1359-1370. doi:10.7150/jca.36083
[Abstract] [Full text] [PDF]

Practice of the New Integrated Molecular Diagnostics in Gliomas: Experiences and New Findings in a Single Chinese Center
Wan-Ming Hu, Fang Wang, Shao-Yan Xi, Xiao Zhang, Jun-Peng Lai, Hui-Yu Wu, Li-Ling Liu, Ke Sai, Jing Zeng
J. Cancer 2020; 11(6): 1371-1382. doi:10.7150/jca.38603
[Abstract] [Full text] [PDF]

Long non-coding RNA TCL6 enhances preferential toxicity of paclitaxel to renal cell carcinoma cells
Zhizhao Chen, Quan Zhuang, Ke Cheng, Yingzi Ming, Yujun Zhao, Qifa Ye, Sheng Zhang
J. Cancer 2020; 11(6): 1383-1392. doi:10.7150/jca.32552
[Abstract] [Full text] [PDF]

Identification of key genes and pathways associated with esophageal squamous cell carcinoma development based on weighted gene correlation network analysis
Mingrui Shao, Wenya Li, Shiyang Wang, Zhenghua Liu
J. Cancer 2020; 11(6): 1393-1402. doi:10.7150/jca.30699
[Abstract] [Full text] [PDF]

Downregulation of EVI1 Expression Inhibits Cell Proliferation and Induces Apoptosis in Hilar Cholangiocarcinoma via the PTEN/AKT Signalling Pathway
Xiao-ming Zhang, Zeng-li Liu, Bo Qiu, Yun-fei XU, Chang Pan, Zong-li Zhang
J. Cancer 2020; 11(6): 1412-1423. doi:10.7150/jca.31903
[Abstract] [Full text] [PDF]

The microRNA212 regulated PEA15 promotes ovarian cancer progression by inhibiting of apoptosis
Yonghong Luo, Chuanchuan Fang, Lan Jin, Huafeng Ding, Yuanyuan Lyu, Guantai Ni
J. Cancer 2020; 11(6): 1424-1435. doi:10.7150/jca.32886
[Abstract] [Full text] [PDF]

Triple-high expression of phosphatase and tensin homolog (PTEN), estrogen receptor (ER) and progesterone receptor (PR) may predict favorable prognosis for patients with Type I endometrial carcinoma
Yanfang Liang, Bihua Lin, Ziyu Ye, Shasha Chen, Haibo Yu, Can Chen, Xin Zhang, Keyuan Zhou, Jincheng Zeng
J. Cancer 2020; 11(6): 1436-1445. doi:10.7150/jca.33720
[Abstract] [Full text] [PDF]

The miR-34 family and its clinical significance in ovarian cancer
Hannah Welponer, Irina Tsibulak, Verena Wieser, Christine Degasper, Giridhar Shivalingaiah, Sören Wenzel, Susanne Sprung, Christian Marth, Hubert Hackl, Heidelinde Fiegl, Alain G. Zeimet
J. Cancer 2020; 11(6): 1446-1456. doi:10.7150/jca.33831
[Abstract] [Full text] [PDF]

p16 promotes proliferation in cervical carcinoma cells through CDK6-HuR-IL1A axis
Mingzhe Li, Jiong Yang, Kaiyu Liu, Jianming Yang, Xiangwen Zhan, Le Wang, Xiaomeng Shen, Jing Chen, Zebin Mao
J. Cancer 2020; 11(6): 1457-1467. doi:10.7150/jca.35479
[Abstract] [Full text] [PDF]

LncRNA00518 promotes cell proliferation through regulating miR-101 in bladder cancer
Kunpeng Wang, Long Ma, Jingyuan Tang, Qiu Yu, Yang Shen, Yunfei Wei, Chen Zhu, Zhonglei Deng, Wei Zhang
J. Cancer 2020; 11(6): 1468-1477. doi:10.7150/jca.35710
[Abstract] [Full text] [PDF]

Alteration of CYP4A11 expression in renal cell carcinoma: diagnostic and prognostic implications
Sup Kim, Jin Man Kim, Hyo Jin Lee, Jae Sung Lim, In-Ock Seong, Kyung-Hee Kim
J. Cancer 2020; 11(6): 1478-1485. doi:10.7150/jca.36438
[Abstract] [Full text] [PDF]

LRG1 Suppresses Migration and Invasion of Esophageal Squamous Cell Carcinoma by Modulating Epithelial to Mesenchymal Transition
Ninggang Zhang, Yaqiong Ren, Yusheng Wang, Lei Zhao, Bin Wang, Nina Ma, Zhengxing Gao, Bangwei Cao
J. Cancer 2020; 11(6): 1486-1494. doi:10.7150/jca.36189
[Abstract] [Full text] [PDF]

Functional characterization of full-length BARD1 strengthens its role as a tumor suppressor in neuroblastoma
Flora Cimmino, Marianna Avitabile, Vito Alessandro Lasorsa, Lucia Pezone, Antonella Cardinale, Annalaura Montella, Sueva Cantalupo, Achille Iolascon, Mario Capasso
J. Cancer 2020; 11(6): 1495-1504. doi:10.7150/jca.36164
[Abstract] [Full text] [PDF]

Prognostic Nomogram and Predictive Factors in Refractory or Relapsed Diffuse Large B-Cell Lymphoma Patients Failing Front-Line R-CHOP Regimens
Shiyu Jiang, Yan Qin, Peng Liu, Jianliang Yang, Sheng Yang, Xiaohui He, Shengyu Zhou, Lin Gui, Changgong Zhang, Liqiang Zhou, Yan Sun, Yuankai Shi
J. Cancer 2020; 11(6): 1516-1524. doi:10.7150/jca.36997
[Abstract] [Full text] [PDF]

Comparison of EML4-ALK fusion gene positive rate in different detection methods and samples of non-small cell lung cancer
Shan Lu, Can Lu, YuXuan Xiao, Wei Zhu, QiuYan He, Bin Xie, JianHua Zhou, YongGuang Tao, Shuang Liu, DeSheng Xiao
J. Cancer 2020; 11(6): 1525-1531. doi:10.7150/jca.36580
[Abstract] [Full text] [PDF]

Prognosis for different patterns of distant metastases in patients with uterine cervical cancer: a population-based analysis
Yiran Zhang, Ying Guo, Xinzi Zhou, Xuena Wang, Xiaofei Wang
J. Cancer 2020; 11(6): 1532-1541. doi:10.7150/jca.37390
[Abstract] [Full text] [PDF]

Genome-wide Analysis of the Alternative Splicing Profiles Revealed Novel Prognostic Index for Kidney Renal Cell Clear Cell Carcinoma
Li Gao, Rong-quan He, Zhi-guang Huang, Yi-wu Dang, Yong-yao Gu, Hai-biao Yan, Sheng-hua Li, Gang Chen
J. Cancer 2020; 11(6): 1542-1554. doi:10.7150/jca.36998
[Abstract] [Full text] [PDF]

Tumour-Infiltrating Immune Cell-Based Subtyping and Signature Gene Analysis in Breast Cancer Based on Gene Expression Profiles
Jingxin Jiang, Weiwei Pan, Yazhang Xu, Chao Ni, Dan Xue, Zhigang Chen, Wuzhen Chen, Jian Huang
J. Cancer 2020; 11(6): 1568-1583. doi:10.7150/jca.37637
[Abstract] [Full text] [PDF]

Effects of Galectin-1 on Biological Behavior in Cervical Cancer
Mandika Chetry, Yizuo Song, Chunyu Pan, Ruyi Li, Jianan Zhang, Xueqiong Zhu
J. Cancer 2020; 11(6): 1584-1595. doi:10.7150/jca.38538
[Abstract] [Full text] [PDF]

Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma
Qiaoshi Xu, Hanyue Chang, Xuerui Tian, Chao Lou, Hailong Ma, Xi Yang
J. Cancer 2020; 11(6): 1596-1605. doi:10.7150/jca.38217
[Abstract] [Full text] [PDF]

Pleurodesis and Immunotherapy in NSCLC; Medical Thoracoscopy or VATS?
Paul Zarogoulidis, Haidong Huang, Meng Yang, Jun Zhou, Yang Jiao, Qin Wang, Dimitris Petridis, Konstantinos Sapalidis, Chrysanthi Sardeli, Parthenopi Konsta, Charilaos Koulouris, Nikolaos Michalopoulos, Dimitrios Giannakidis, Nikolaos Barbetakis, Athanasios Katsaounis, Wolfgang Hohenforst-Schmidt, Aikaterini Amaniti, Savvas Petanidis, Kosmas Tsakiridis, Nikolaos Courcoutsakis, Alexandru Marian Goganau, Anastasios Vagionas, Konstantinos Romanidis, Panagoula Oikonomou, Michael Karanikas, Iason Nikolaos Katsios, Isaak Kesisoglou, Christoforos Kosmidis
J. Cancer 2020; 11(6): 1606-1613. doi:10.7150/jca.40004
[Abstract] [Full text] [PDF]

MiR-142-3p functions as an oncogene in prostate cancer by targeting FOXO1
Yi-Fan Tan, Zhi-Yuan Chen, Lei Wang, Min Wang, Xiu-Heng Liu
J. Cancer 2020; 11(6): 1614-1624. doi:10.7150/jca.41888
[Abstract] [Full text] [PDF]

LZAP promotes the proliferation and invasiveness of cervical carcinoma cells by targeting AKT and EMT
Yi-Fang Dai, Na Lin, De-Qin He, Mu Xu, Li-Ying Zhong, Shu-Qiong He, Dan-Hua Guo, Ying Li, Hai-Long Huang, Xiang-Qing Zheng, Liang-Pu Xu
J. Cancer 2020; 11(6): 1625-1633. doi:10.7150/jca.39359
[Abstract] [Full text] [PDF]

Choice of Treatment for Stage IA Non-small Cell Lung Cancer Patients Ineligible for Surgery: Ablation or Stereotactic Body Radiotherapy?
Long Liang, Guoshu Li, Shuanshuan Xie, Guifeng Sun, Mengmei Zhang, Fenyong Sun, Aimei Peng
J. Cancer 2020; 11(6): 1634-1640. doi:10.7150/jca.39465
[Abstract] [Full text] [PDF]

Effects of MACC1 polymorphisms on hepatocellular carcinoma development and clinical characteristics
Chien-Hua Lin, Ming-Ju Hsieh, Hsiang-Lin Lee, Shun-Fa Yang, Shih-Chi Su, Wei-Jiunn Lee, Ying-Erh Chou
J. Cancer 2020; 11(6): 1641-1647. doi:10.7150/jca.38856
[Abstract] [Full text] [PDF]

Reviews

MicroRNA-183 in Cancer Progression
Dingren Cao, Min Di, Jingjie Liang, Shuang Shi, Qiang Tan, Zhengguang Wang
J. Cancer 2020; 11(6): 1315-1324. doi:10.7150/jca.39044
[Abstract] [Full text] [PDF]

The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
Ligong Chang, Surong Fang, Wei Gu
J. Cancer 2020; 11(6): 1403-1411. doi:10.7150/jca.31406
[Abstract] [Full text] [PDF]

Molecular Mechanism of Pancreatic Stellate Cells Activation in Chronic Pancreatitis and Pancreatic Cancer
Guihua Jin, Weilong Hong, Yangyang Guo, Yongheng Bai, Bicheng Chen
J. Cancer 2020; 11(6): 1505-1515. doi:10.7150/jca.38616
[Abstract] [Full text] [PDF]

Progress in Animal Models of Pancreatic Ductal Adenocarcinoma
Kaiwen Kong, Meng Guo, Yanfang Liu, Jianming Zheng
J. Cancer 2020; 11(6): 1555-1567. doi:10.7150/jca.37529
[Abstract] [Full text] [PDF]