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Volume 10 (24); 2019

Research Papers

Establishing the prediction models for recurrence and progression of T1G3 bladder urothelial carcinoma
Song Chen, Mengxin Lu, Tianchen Peng, Yejinpeng Wang, Xuefeng Liu, Yu Xiao, Xinghuan Wang
J. Cancer 2019; 10(24): 5891-5902. doi:10.7150/jca.35866
[Abstract] [Full text] [PDF]

Expression of EMT-Related Genes CAMK2N1 and WNT5A is increased in Locally Invasive and Metastatic Prostate Cancer
Isa Carneiro, Filipa Quintela-Vieira, João Lobo, Catarina Moreira-Barbosa, Francisco Duarte Menezes, Ana Teresa Martins, Jorge Oliveira, Regina Silva, Carmen Jerónimo, Rui Henrique
J. Cancer 2019; 10(24): 5915-5925. doi:10.7150/jca.34564
[Abstract] [Full text] [PDF]

Impact of primary tumor location in patients with RAS wild-type metastatic colon cancer treated with first-line chemotherapy plus anti-EGFR or anti-VEGF monoclonal antibodies: a retrospective multicenter study
Antonino Grassadonia, Pietro Di Marino, Corrado Ficorella, Alessio Cortellini, Katia Cannita, Alessandro Parisi, Teresa Gamucci, Federica Zoratto, Patrizia Vici, Maddalena Barba, Ettore Porreca, Matteo Neri, Angelo Veronese, Clara Natoli, Michele De Tursi, Nicola Tinari
J. Cancer 2019; 10(24): 5926-5934. doi:10.7150/jca.34550
[Abstract] [Full text] [PDF]

Independent effect of postoperative neutrophil-to-lymphocyte ratio on the survival of pancreatic ductal adenocarcinoma with open distal pancreatosplenectomy and its nomogram-based prediction
Ning Pu, Hanlin Yin, Guochao Zhao, Abulimiti Nuerxiati, Dansong Wang, Xuefeng Xu, Tiantao Kuang, Dayong Jin, Wenhui Lou, Wenchuan Wu
J. Cancer 2019; 10(24): 5935-5943. doi:10.7150/jca.35856
[Abstract] [Full text] [PDF]

A novel and validated nomogram to predict overall survival for gastric neuroendocrine neoplasms
Sheng Zhang, Yi Xin Tong, Xin Hua Zhang, Yu Jie Zhang, Xiang Shang Xu, Ai Tang Xiao, Teng Fei Chao
J. Cancer 2019; 10(24): 5944-5954. doi:10.7150/jca.35785
[Abstract] [Full text] [PDF]

HIF-1α rs11549465 C>T polymorphism contributes to increased cancer susceptibility: Evidence from 49 studies
Hu-Nian Li, Ting He, Yong-Jiu Zha, Fang Du, Jie Liu, Hui-Ran Lin, Wen-Zi Yang
J. Cancer 2019; 10(24): 5955-5963. doi:10.7150/jca.35716
[Abstract] [Full text] [PDF]

Cip2a/miR-301a feedback loop promotes cell proliferation and invasion of triple-negative breast cancer
Jiang Yin, Danyang Chen, Kai Luo, Minying Lu, Yixue Gu, Shanshan Zeng, Xiangzhou Chen, Ying Song, Zhijie Zhang, Guopei Zheng, Zhimin He, Hao Liu
J. Cancer 2019; 10(24): 5964-5974. doi:10.7150/jca.35704
[Abstract] [Full text] [PDF]

Long-term Results of Conversion Therapy for Initially Unresectable Gastric Cancer: Analysis of 122 Patients at the National Cancer Center in China
Tongbo Wang, Nianchang Wang, Hu Ren, Hong Zhou, Aiping Zhou, Jing Jin, Yingtai Chen, Dongbing Zhao
J. Cancer 2019; 10(24): 5975-5985. doi:10.7150/jca.35527
[Abstract] [Full text] [PDF]

Intraoperative Chemotherapy with a Novel Regimen Improved the Therapeutic Outcomes of Colorectal Cancer
Zhihua Liu, Yifeng Zou, Yuming Rong, Xingyuan Shi, Chen Li, Chao Li, Yinghai Tian, Hongcheng Lin, Min Liu, Jinsheng Weng, Ting Liu, Xiaomei Li, Chao Lei, Weipeng Li, Xinke Zhou
J. Cancer 2019; 10(24): 5986-5991. doi:10.7150/jca.35450
[Abstract] [Full text] [PDF]

The Value of LncRNA BCAR4 as a Prognostic Biomarker on Clinical Outcomes in Human Cancers
Chao Tu, Xiaolei Ren, Jieyu He, Chenghao Zhang, Ruiqi Chen, Wanchun Wang, Zhihong Li
J. Cancer 2019; 10(24): 5992-6002. doi:10.7150/jca.35113
[Abstract] [Full text] [PDF]

Long non-coding RNA LOC554202 promotes acquired gefitinib resistance in non-small cell lung cancer through upregulating miR-31 expression
Jing He, Shidai Jin, Wei Zhang, Deqin Wu, Jun Li, Jing Xu, Wen Gao
J. Cancer 2019; 10(24): 6003-6013. doi:10.7150/jca.35097
[Abstract] [Full text] [PDF]

Suppression of non-small cell lung cancer migration and invasion by hsa-miR-486-5p via the TGF-β/SMAD2 signaling pathway
Tao Chen, Jianjie Zhu, Tingting Cai, Wenwen Du, Yang Zhang, Qingqing Zhu, Zeyi Liu, Jian-an Huang
J. Cancer 2019; 10(24): 6014-6024. doi:10.7150/jca.35017
[Abstract] [Full text] [PDF]

Downregulated Salt-inducible Kinase 3 Expression Promotes Chemoresistance in Serous Ovarian Cancer via the ATP‐binding Cassette Protein ABCG2
Yu-Ling Liang, Chin-Han Wu, Chieh-Yi Kang, Chang-Ni Lin, Neng-Yao Shih, Sheng-Hsiang Lin, Yeong-Chang Chen, Keng-Fu Hsu
J. Cancer 2019; 10(24): 6025-6036. doi:10.7150/jca.34886
[Abstract] [Full text] [PDF]

Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway
Yu Liang, Danxi Zhu, Liming Zhu, Yichao Hou, Lidan Hou, Xin Huang, Linjing Li, Yu Wang, Lei Li, Huimin Zou, Tianqi Wu, Mengfei Yao, Jianhua Wang, Xiangjun Meng
J. Cancer 2019; 10(24): 6037-6047. doi:10.7150/jca.34650
[Abstract] [Full text] [PDF]

High expression of CHML predicts poor prognosis of multiple myeloma
Weilong Zhang, Ling Cao, Xiaoni Liu, Xue He, Ye Zhang, Zuozhen Yang, Ping Yang, Jing Wang, Kai Hu, Xiuru Zhang, Weiyou Liu, Xiaoliang Yuan, Hongmei Jing
J. Cancer 2019; 10(24): 6048-6056. doi:10.7150/jca.34465
[Abstract] [Full text] [PDF]

Dihydroartemisinin Induces Endothelial Cell Autophagy through Suppression of the Akt/mTOR Pathway
Jing Liu, Yanjun Ren, Yinglong Hou, Caiqing Zhang, Bei Wang, Xiaorui Li, Rong Sun, Ju Liu
J. Cancer 2019; 10(24): 6057-6064. doi:10.7150/jca.33704
[Abstract] [Full text] [PDF]

NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma
Huan Li, Zihui Yang, Weiqi Wang, Jun Wang, Jianying Zhang, Junye Liu, Tao Yang, Yaowu Yang, Jianhua Wei, Delin Lei, Xinjie Yang
J. Cancer 2019; 10(24): 6065-6073. doi:10.7150/jca.33635
[Abstract] [Full text] [PDF]

Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma
Nan Tian, Wenbing Shangguan, Zuolin Zhou, Yao yao, Chunlei Fan, Lijun Cai
J. Cancer 2019; 10(24): 6074-6087. doi:10.7150/jca.33421
[Abstract] [Full text] [PDF]

High expression of DOCK2 indicates good prognosis in acute myeloid leukemia
Ning Hu, Yifan Pang, Hongmian Zhao, Chaozeng Si, Hui Ding, Li Chen, Chao Wang, Tong Qin, Qianyu Li, Yu Han, Yifeng Dai, Yijie Zhang, Jinlong Shi, Depei Wu, Xinyou Zhang, Zhiheng Cheng, Lin Fu
J. Cancer 2019; 10(24): 6088-6094. doi:10.7150/jca.33244
[Abstract] [Full text] [PDF]

Establishment and Characterization of a CTC Cell Line from Peripheral Blood of Breast Cancer Patient
Pan Zhao, Wenbin Zhou, Chang Liu, Huirong Zhang, Zhiqiang Cheng, Weiqing Wu, Kaisheng Liu, Hong Hu, Caineng Zhong, Yayuan Zhang, Dongxian Zhou, Feiyuan Liu, Yong Dai, Jianhong Wang, Chang Zou
J. Cancer 2019; 10(24): 6095-6104. doi:10.7150/jca.33157
[Abstract] [Full text] [PDF]

Indirect comparison between immune checkpoint inhibitors and targeted therapies for the treatment of melanoma
Minliang Wu, Yuchong Wang, Yalong Xu, Ji Zhu, Chuan Lv, Mengyan Sun, Rui Guo, Yu Xia, Wei Zhang, Chunyu Xue
J. Cancer 2019; 10(24): 6114-6123. doi:10.7150/jca.32638
[Abstract] [Full text] [PDF]

Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin
Yaojun Peng, Li Wang, Liangliang Wu, Ling Zhang, Guangjun Nie, Mingzhou Guo
J. Cancer 2019; 10(24): 6124-6134. doi:10.7150/jca.32511
[Abstract] [Full text] [PDF]

Plan quality comparison for cervical carcinoma treated with Halcyon and Trilogy intensity-modulated radiotherapy
Chengqiang Li, Jinhu Chen, Jian Zhu, Guanzhong Gong, Cheng Tao, Zhenjiang Li, Jie Lu, Yong Yin
J. Cancer 2019; 10(24): 6135-6141. doi:10.7150/jca.32500
[Abstract] [Full text] [PDF]

DNA Replication and Sister Chromatid Cohesion 1 (DSCC1) of the Replication Factor Complex CTF18-RFC is Critical for Colon Cancer Cell Growth
Jong-Tae Kim, Hee Jun Cho, Sang Yoon Park, Byung Moo Oh, Yo Sep Hwang, Kyoung Eun Baek, Young-Ha Lee, Hee Cheol Kim, Hee Gu Lee
J. Cancer 2019; 10(24): 6142-6153. doi:10.7150/jca.32339
[Abstract] [Full text] [PDF]

Long-term cardiac-specific mortality among 44,292 acute myeloid leukemia patients treated with chemotherapy: a population-based analysis
Guangli Li, Zhijuan Zhou, Wencong Yang, Hao Yang, Xiuwu Fan, Yuelan Yin, Liyun Luo, Jinyou Zhang, Niujian Wu, Zibin Liang, Jianting Ke, Jian Chen
J. Cancer 2019; 10(24): 6161-6169. doi:10.7150/jca.36948
[Abstract] [Full text] [PDF]

Genetic variants in RTEL1 influencing telomere length are associated with prostate cancer risk
Cheng-Yuan Gu, Sheng-Ming Jin, Xiao-Jian Qin, Yao Zhu, Dai Bo, Guo-Wen Lin, Guo-Hai Shi, Ding-Wei Ye
J. Cancer 2019; 10(24): 6170-6174. doi:10.7150/jca.35917
[Abstract] [Full text] [PDF]

Clinical Implications of Tumor-Infiltrating Immune Cells in Breast Cancer
Shi-Chao Zhang, Zu-Quan Hu, Jin-Hua Long, Gui-Ming Zhu, Yun Wang, Yi Jia, Jing Zhou, Yan Ouyang, Zhu Zeng
J. Cancer 2019; 10(24): 6175-6184. doi:10.7150/jca.35901
[Abstract] [Full text] [PDF]

Reviews

Eribulin in Triple Negative Metastatic Breast Cancer: Critic Interpretation of Current Evidence and Projection for Future Scenarios
Laura Pizzuti, Eriseld Krasniqi, Giacomo Barchiesi, Marco Mazzotta, Maddalena Barba, Antonella Amodio, Gioia Massimiani, Fabio Pelle, Ramy Kayal, Enrico Vizza, Antonino Grassadonia, Silverio Tomao, Aldo Venuti, Teresa Gamucci, Paolo Marchetti, Clara Natoli, Giuseppe Sanguineti, Gennaro Ciliberto, Patrizia Vici
J. Cancer 2019; 10(24): 5903-5914. doi:10.7150/jca.35109
[Abstract] [Full text] [PDF]

CircRNAs and its relationship with gastric cancer
Xinxin Fang, Jing Wen, Mingjun Sun, Yuan Yuan, Qian Xu
J. Cancer 2019; 10(24): 6105-6113. doi:10.7150/jca.32927
[Abstract] [Full text] [PDF]

Potential Therapeutic Roles of Exosomes in Multiple Myeloma: A Systematic Review
Mengzhen Li, Bing Xia, Yi Wang, M. James You, Yizhuo Zhang
J. Cancer 2019; 10(24): 6154-6160. doi:10.7150/jca.31752
[Abstract] [Full text] [PDF]