◂ Last issue Archive   

Volume 16 (10); 2025

Research Papers

Graphic abstract

Pembrolizumab versus Pembrolizumab plus Chemotherapy in Non-small Cell Lung Cancer with High PD-L1 Expression - Multicenter Real-world Evidence Study
Martin Svaton, Magdalena Knetki-Wroblewska, Petr Hosek, Gabriela Chowaniecova, Jan Spacek, Ondrej Fischer, Ondrej Bilek, Michal Hrnciarik, Diego Kauffmann-Guerrero
J. Cancer 2025; 16(10): 3015-3023. doi:10.7150/jca.113815
Full text PDF


Graphic abstract

Nit1 is upregulated in non-small cell lung cancer and promotes cancer cell proliferation and invasion and regulates EMT-related molecules and cyclins
Jian Wang, Biying Jiang, Xiaojing Wang, Haifeng Liu, Chuifeng Fan
J. Cancer 2025; 16(10): 3040-3047. doi:10.7150/jca.96095
Full text PDF


Graphic abstract

Study on the mechanism of gracillin inhibiting the proliferation of lung cancer NCI-H1299 cells based on MAPK signaling pathway
Bang Xiao, Minhong Zhang, Hai Liu, Aiping Cui, Yihe Tian, Fosheng Tang, Shichen Liao, Mingchun Li, Hao Huang, Weijie Peng, Jianqiong Yang
J. Cancer 2025; 16(10): 3048-3064. doi:10.7150/jca.113694
Full text PDF


Graphic abstract

Impact of PIK3CA Mutations on the Clinical Benefits of CDK 4/6 Inhibitors in HR+/HER2- Advanced Breast Cancer: An Updated Pairwise and Network Meta-Analysis
Sheng-Fan Wang, Chian-Ying Chou, Yi-Wen Chao, Tzu-Kuan Chan, Wan-Yu Yeh, Chern-En Chiang, Chen-Huan Chen, Hsin-Chen Lee, Ling-Ming Tseng, Yuh-Lih Chang, Hao-Min Cheng, Chun-Yu Liu
J. Cancer 2025; 16(10): 3065-3079. doi:10.7150/jca.111362
Full text PDF


Graphic abstract

RBM10 inhibits pancreatic cancer development by suppressing immune escape through PD-1 expression
Xia Gao, Xiuqin Zhang, Junjie Huang, Zhenyu Tan, Jing Yang, Liuhong Yuan, Pengjun Wang, Feier Chen, Huiyan Wu, Changyi Feng, Hong Yu, Shisan Bao, Da Fu, Kun Tao
J. Cancer 2025; 16(10): 3080-3093. doi:10.7150/jca.111459
Full text PDF


Graphic abstract

Investigation of CBX4 Polymorphisms and Their Association with Clinicopathological Features in Asian Patients with Oral Squamous Cell Carcinoma
Li-Chung Hung, Yi-Chung Chien, Chiao-Wen Lin, Chun-Yi Chuang, Hsiu-San Hsu, Liang-Chih Liu, Shun-Fa Yang, Yung-Luen Yu
J. Cancer 2025; 16(10): 3094-3102. doi:10.7150/jca.116232
Full text PDF


Graphic abstract

Characteristics of Non-mass Enhancement in Contrast-enhanced Breast MRI and Associations with Malignancy
Kamber Goksu, Ahmet Vural, Ahmet Nedim Kahraman
J. Cancer 2025; 16(10): 3103-3111. doi:10.7150/jca.114087
Full text PDF


Graphic abstract

Unlocking ESCC Progression: CCL15-CCR1 Axis Activates AKT/ERK1/2/c-Jun/CDK2 Pathway
Shengliang He, Yunjiu Gou, Qizhou Bo, Dacheng Jin, Songchen Han, Hui Cai
J. Cancer 2025; 16(10): 3112-3127. doi:10.7150/jca.113925
Full text PDF

Review

Graphic abstract

Predictive and Prognostic Biomarkers of Recurrence in Locoregional Colorectal Cancer
Alicia Sánchez Cendra, Leonel Pekarek, Linda Rocio Ospino, Yumna Dbouk, Sami Chnaiker, Ana Luengo, Tania Villamor, Amalia Corralo, Beatriz Pedrejon, Tatiana Pekarek, Silvestra Barrena-Blázquez, David Díaz-Pérez, Ana M Minaya-Bravo, Laura López-Gonzalez, Manuel Díez Alonso, Tomás Ratia Giménez, Alberto Gutiérrez-Calvo, Melchor Álvarez-Mon, Javier Cassinello Espinosa, Raúl Díaz-Pedrero, Miguel A Ortega
J. Cancer 2025; 16(10): 3024-3039. doi:10.7150/jca.111828
Full text PDF

Popup Image