J Cancer 2024; 15(8):2193-2205. doi:10.7150/jca.93885 This issue Cite

Review

Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns

Ya'ning Zhao1, Jun Bai2, Xi Wang2, Yaoren Zhang3, Xiaohong Yan1, Jun'an Qi4, Xueyan Xia2, Yuansong Feng2, Baojun Duan1,2✉

1. Department of Medical Oncology of Baoji Central Hospital, Baoji 721008, Shaanxi Province, China.
2. Department of Medical Oncology of Shaanxi Provincial People's Hospital, Xi'an 710068, Shaanxi Province, China.
3. Department of Ultrasonography of Baoji Central Hospital, Baoji 721008, Shaanxi Province, China.
4. Department of Hepatobiliary Surgery of Baoji Central Hospital, Baoji 721008, Shaanxi Province, China.

Citation:
Zhao Y, Bai J, Wang X, Zhang Y, Yan X, Qi J, Xia X, Feng Y, Duan B. Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns. J Cancer 2024; 15(8):2193-2205. doi:10.7150/jca.93885. https://www.jcancer.org/v15p2193.htm
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Abstract

Graphic abstract

With the development of guidance technology and ablation equipment, ablative procedures have emerged as important loco-regional alternatives to surgical resection for recurrent hepatocellular carcinoma (rHCC) patients. Currently, ablation modalities used in clinical practice mainly include radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation (LA), cryoablation (CRA), high-intensity focused ultrasound (HIFU), and irreversible electroporation (IRE). Accumulated comparative data of ablation versus surgical resection reveal noninferior responses and outcomes but superior adverse effects. Moreover, studies demonstrate that ablation may serve as an excellent procedure for rHCC given its exact minimal invasiveness and immune modulation. We focus on the current status of ablation in clinical practice for rHCC and discuss new research in the field, including ablation combined with these other modalities, such as targeted therapy and immunotherapy.

Keywords: Ablation, HCC, RFA, MWA


Citation styles

APA
Zhao, Y., Bai, J., Wang, X., Zhang, Y., Yan, X., Qi, J., Xia, X., Feng, Y., Duan, B. (2024). Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns. Journal of Cancer, 15(8), 2193-2205. https://doi.org/10.7150/jca.93885.

ACS
Zhao, Y.; Bai, J.; Wang, X.; Zhang, Y.; Yan, X.; Qi, J.; Xia, X.; Feng, Y.; Duan, B. Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns. J. Cancer 2024, 15 (8), 2193-2205. DOI: 10.7150/jca.93885.

NLM
Zhao Y, Bai J, Wang X, Zhang Y, Yan X, Qi J, Xia X, Feng Y, Duan B. Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns. J Cancer 2024; 15(8):2193-2205. doi:10.7150/jca.93885. https://www.jcancer.org/v15p2193.htm

CSE
Zhao Y, Bai J, Wang X, Zhang Y, Yan X, Qi J, Xia X, Feng Y, Duan B. 2024. Threatment Strategies for Recurrent Hepatocellular Carcinoma Patients: Ablation and its Combination Patterns. J Cancer. 15(8):2193-2205.

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