1. Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-Inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-Inflammatory and Immune Medicine, Hefei, China. 2. The First Affiliated Hospital of Anhui Medical University. #These authors equally contributed to this paper.
Tan X, Jiang H, Fang Y, Han D, Guo Y, Wang X, Gong X, Hong W, Tu J, Wei W. The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker. J Cancer 2021; 12(1):224-231. doi:10.7150/jca.49203. https://www.jcancer.org/v12p0224.htm
Glioma is a malignant brain tumor with a generally poor prognosis. Dysregulation of a long non-coding RNA, GAS5, has been detected in numerous cancers, including glioma. Previous studies have suggested that GAS5 plays a significant functional role in glioma, affecting proliferation, metastasis, invasion, and apoptosis. In this review, we describe the roles and mechanisms of GAS5 in glioma. GAS5 may be a biomarker for diagnosis and prognosis, and even a potential target for glioma treatment, and therefore warrants further investigation.
Keywords: GAS5, miRNA, glioma, chemosensitivity
Citation styles
APA
Tan, X., Jiang, H., Fang, Y., Han, D., Guo, Y., Wang, X., Gong, X., Hong, W., Tu, J., Wei, W. (2021). The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker. Journal of Cancer, 12(1), 224-231. https://doi.org/10.7150/jca.49203.
ACS
Tan, X.; Jiang, H.; Fang, Y.; Han, D.; Guo, Y.; Wang, X.; Gong, X.; Hong, W.; Tu, J.; Wei, W. The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker. J. Cancer 2021, 12 (1), 224-231. DOI: 10.7150/jca.49203.
NLM
Tan X, Jiang H, Fang Y, Han D, Guo Y, Wang X, Gong X, Hong W, Tu J, Wei W. The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker. J Cancer 2021; 12(1):224-231. doi:10.7150/jca.49203. https://www.jcancer.org/v12p0224.htm
CSE
Tan X, Jiang H, Fang Y, Han D, Guo Y, Wang X, Gong X, Hong W, Tu J, Wei W. 2021. The essential role of long non-coding RNA GAS5 in glioma: interaction with microRNAs, chemosensitivity and potential as a biomarker. J Cancer. 12(1):224-231.
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