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Volume 11 (19); 2020

Research Papers

Reduction of Polyunsaturated Fatty Acids with Tumor Progression in a Lean Non-Alcoholic Steatohepatitis-Associated Hepatocellular Carcinoma Mouse Model
Elizabeth M Vlock, Shilpa Karanjit, Geoffrey Talmon, Paraskevi A Farazi
J. Cancer 2020; 11(19): 5536-5546. doi:10.7150/jca.48495
[Abstract] [Full text] [PDF]

The development of bronchoscopy in China: a national cross-sectional study
Dongchen Shi, Fuqi Li, Kaicheng Wang, Chen Kong, Haidong Huang, Qiang Li, Faguang Jin, Chengping Hu, Changhui Wang, Hui Shi, Zhenli Hu, Yuchao Dong, Yunye Ning, Kosmas Tsakiridis, Konstantinos Sapalidis, Christoforos Kosmidis, Anastasios Vagionas, Wolfgang Hohenforst-Schmidt, Lutz Freitag, J Francis Turner, Konstantinos Drevelegas, Eleni-Isidora Perdikouri, Tomi Kovacevic, Tatjana Sarcev, Bojan Zaric, Savas Petanidis, Sofia Baka, Ioannis Boukovinas, Stylianos Kakolyris, Paul Zarogoulidis, Chong Bai
J. Cancer 2020; 11(19): 5547-5555. doi:10.7150/jca.47183
[Abstract] [Full text] [PDF]

Genome-wide RNA-sequencing dataset reveals the prognostic value and potential molecular mechanisms of lncRNA in non-homologous end joining pathway 1 in early stage Pancreatic Ductal Adenocarcinoma
Li-Ming Shang, Xi-Wen Liao, Guang-Zhi Zhu, Ke-Tuan Huang, Chuang-Ye Han, Cheng-Kun Yang, Xiang-Kun Wang, Xin Zhou, Hao Su, Xin-Ping Ye, Tao Peng
J. Cancer 2020; 11(19): 5556-5567. doi:10.7150/jca.39888
[Abstract] [Full text] [PDF]

Gambogic acid affects ESCC progression through regulation of PI3K/AKT/mTOR signal pathway
Jiarui Yu, Wei Wang, Weinan Yao, Zhao Yang, Peng Gao, Meiyue Liu, Huan Wang, Siyuan Chen, Dan Wang, weixi Wang, Guogui Sun
J. Cancer 2020; 11(19): 5568-5577. doi:10.7150/jca.41115
[Abstract] [Full text] [PDF]

SSR2 overexpression associates with tumorigenesis and metastasis of Hepatocellular Carcinoma through modulating EMT
Xiaopeng Hong, Hui Luo, Genglong Zhu, Xiaodong Guan, Yingbin Jia, Hailing Yu, Xiufang Lv, Ting Yu, Huimin Lan, Qianqian Zhang, Hanjie Li, Weiming Sun, Xiaofang Huang, Jian Li
J. Cancer 2020; 11(19): 5578-5587. doi:10.7150/jca.44788
[Abstract] [Full text] [PDF]

Systematic Analysis of the Clinical Relevance of Cell Division Cycle Associated Family in Endometrial Carcinoma
Wenchao Zhang, Xiaofeng Qiu, Di Sun, Danye Zhang, Yue Qi, Xiao Li, Bingying Liu, Juanjuan Liu, Bei Lin
J. Cancer 2020; 11(19): 5588-5600. doi:10.7150/jca.46324
[Abstract] [Full text] [PDF]

Involvement of the NF-κB signaling pathway in proliferation and invasion inhibited by Zwint-1 deficiency in Pancreatic Cancer Cells
Jae Hyeong Kim, Yuna Youn, Jong-chan Lee, Jaihwan Kim, Jin-Hyeok Hwang
J. Cancer 2020; 11(19): 5601-5611. doi:10.7150/jca.46173
[Abstract] [Full text] [PDF]

ALKBH5 regulates IGF1R expression to promote the Proliferation and Tumorigenicity of Endometrial Cancer
Xiaowen Pu, Zhuowei Gu, Zhengrong Gu
J. Cancer 2020; 11(19): 5612-5622. doi:10.7150/jca.46097
[Abstract] [Full text] [PDF]

Developing a selection-aided model to screen Cirrhotic Intrahepatic Cholangiocarcinoma for Hepatectomy
Qinjunjie Chen, Fengwei Li, Yuzhen Gao, Hui Xue, Zheng Li, Qifei Zou, Yong Xia, Kui Wang, Feng Shen
J. Cancer 2020; 11(19): 5623-5634. doi:10.7150/jca.46587
[Abstract] [Full text] [PDF]

Safety, Efficacy, Pharmacokinetic and Pharmacodynamic evaluation of YF-H-2015005 for mobilizing Hematopoietic stem cells in Non-Hodgkin's Lymphoma Patients
Weiping Liu, Yan Xie, Lingyan Ping, Min Jiang, Guanmin Zhang, Yimin Cui, Junyu Xu, Meng Wu, Xin Leng, Xiaopei Wang, Shufang Wang, Jun Zhu, Yuqin Song
J. Cancer 2020; 11(19): 5635-5640. doi:10.7150/jca.48748
[Abstract] [Full text] [PDF]

LINC00355:8 promotes cell proliferation and migration with invasion via the MiR-6777-3p/Wnt10b axis in Hepatocellular Carcinoma
Fangyuan Zhou, Yiming Lei, Xuan Xu, Haoxiong Zhou, Huiling Liu, Jie Jiang, Yidong Yang, Bin Wu
J. Cancer 2020; 11(19): 5641-5655. doi:10.7150/jca.43831
[Abstract] [Full text] [PDF]

High serum Androgen and Insulin concentrations increase the tendency of Endometrial Carcinoma
Fei Teng, Xiaotong Ma, Xiaopei Yu, Ye Yan, Jing Zhao, Jinping Gao, Chao Gao, Yingmei Wang, Wenyan Tian, Fengxia Xue
J. Cancer 2020; 11(19): 5656-5664. doi:10.7150/jca.46391
[Abstract] [Full text] [PDF]

Association of preoperative systemic Immune-inflammation Index and Prognostic Nutritional Index with survival in patients with Upper Tract Urothelial Carcinoma
Yangqin Zheng, Dongdong Yu, Zhixian Yu, Dewei Zhao, Yuming Chen, Wu Chen, Yeping Li, Binwei Lin, Xiaomin Gao
J. Cancer 2020; 11(19): 5665-5677. doi:10.7150/jca.44915
[Abstract] [Full text] [PDF]

TRPV1 acts as a Tumor Suppressor and is associated with Immune Cell Infiltration in Clear Cell Renal Cell Carcinoma: evidence from integrated analysis
Long Zheng, Xiaojie Dou, Huijia Song, Ruixia Gao, Xiaoshuang Tang
J. Cancer 2020; 11(19): 5678-5688. doi:10.7150/jca.45918
[Abstract] [Full text] [PDF]

Dihydromyricetin inhibits cell proliferation, migration, invasion and promotes apoptosis via regulating miR-21 in Human Cholangiocarcinoma Cells
Lei Chen, Zhou-Sheng Yang, Yang-Zhao Zhou, Yang Deng, Pei Jiang, Sheng-Lan Tan
J. Cancer 2020; 11(19): 5689-5699. doi:10.7150/jca.45970
[Abstract] [Full text] [PDF]

LINC00662 sponges miR-107 accelerating the invasiveness and proliferation of glioma cells
Jinsong Wu, Xiaolong Guo, Dongxiao Xu, Hongri Zhang
J. Cancer 2020; 11(19): 5700-5712. doi:10.7150/jca.46381
[Abstract] [Full text] [PDF]

A tropism-transformed Oncolytic Adenovirus with Dual Capsid Modifications for enhanced Glioblastoma Therapy
Lizheng Wang, Wenmo Liu, Zhe Li, Xupu Wang, Xinyao Feng, Zixuan Wang, Jiaxin Wu, Haihong Zhang, Hui Wu, Wei Kong, Bin Yu, Xianghui Yu
J. Cancer 2020; 11(19): 5713-5726. doi:10.7150/jca.46463
[Abstract] [Full text] [PDF]

The diagnostic and prognostic value of cell division cycle associated gene family in Hepatocellular Carcinoma
Bowen Wu, Yu Huang, Yingwan Luo, An Ma, Zhaoxing Wu, Yichao Gan, Ying Xu, Rongzhen Xu
J. Cancer 2020; 11(19): 5727-5737. doi:10.7150/jca.46554
[Abstract] [Full text] [PDF]

Cryotherapy shows no inferiority compared with radical Prostatectomy for low-risk and intermediate-risk localized Prostate Cancer: a real-world study from the SEER database
Kun Jin, Shi Qiu, Xiaonan Zheng, Yanyan Li, Shiyu Zhang, Jiakun Li, Xinyang Liao, Xiang Tu, Lu Yang, Qiang Wei
J. Cancer 2020; 11(19): 5738-5745. doi:10.7150/jca.38323
[Abstract] [Full text] [PDF]

Torin2 inhibits the EGFR-TKI resistant Non-Small Lung Cancer cell proliferation through negative feedback regulation of Akt/mTOR signaling
Yi Hu, Ji Zhang, Qun Liu, Mingyao Ke, Jiurong Li, Wenhao Suo, Weixi Guo, Aiping Ma
J. Cancer 2020; 11(19): 5746-5757. doi:10.7150/jca.37417
[Abstract] [Full text] [PDF]

PM2.5 downregulates MicroRNA-139-5p and induces EMT in Bronchiolar Epithelium Cells by targeting Notch1
Yunxia Wang, Yijue Zhong, Cheng Zhang, Jiping Liao, Guangfa Wang
J. Cancer 2020; 11(19): 5758-5767. doi:10.7150/jca.46976
[Abstract] [Full text] [PDF]

A novel seven-gene signature as Prognostic Biomarker in Hepatocellular Carcinoma
Hui Xie, Shouping Liu, Ziying Zhang, Peng Chen, Yongguang Tao
J. Cancer 2020; 11(19): 5768-5781. doi:10.7150/jca.44573
[Abstract] [Full text] [PDF]

Conditional Survival of female patients with operable invasive Breast Cancer in US: A population-based study
Bolun Ai, Xiangyu Wang, Xiangyi Kong, Zhongzhao Wang, Yi Fang, Jing Wang
J. Cancer 2020; 11(19): 5782-5791. doi:10.7150/jca.46183
[Abstract] [Full text] [PDF]

Clinical Significance of Paraspinal Muscle Parameters as a prognostic factor for survival in Gastric Cancer Patients who underwent Curative Surgical Resection
Wankyu Eo, Jungmi Kwon, Soomin An, Sookyung Lee, Sehyun Kim, Dongwoo Nam, Ga Young Han, Sung Il Choi, Ho-Yeon Chung
J. Cancer 2020; 11(19): 5792-5801. doi:10.7150/jca.46637
[Abstract] [Full text] [PDF]

Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway
Jingjing Liu, Hongsheng Liang, Saadia Khilji, Haitao Li, Dandan Song, Chen Chen, Xiaoxing Wang, Yiwei Zhang, Ning Zhao, Xina Li, Aili Gao
J. Cancer 2020; 11(19): 5802-5811. doi:10.7150/jca.46697
[Abstract] [Full text] [PDF]

Differences in tumour characteristics of Hepatocellular Carcinoma between patients with and without Cirrhosis: A population-based study
Bing Yan, Dou-Sheng Bai, Jian-Jun Qian, Chi Zhang, Sheng-Jie Jin, Xuehao Wang, Guo-Qing Jiang
J. Cancer 2020; 11(19): 5812-5821. doi:10.7150/jca.46927
[Abstract] [Full text] [PDF]

Genetic variants in the Folic acid Metabolic Pathway Genes predict outcomes of metastatic Colorectal Cancer patients receiving first-line Chemotherapy
Lu Jiang, Shuwei Li, Ming Yuan, Ling Ma, Yu Lin, Weiyou Zhu, Haina Du, Meilin Wang, Tao Chen, Lingjun Zhu
J. Cancer 2020; 11(19): 5822-5830. doi:10.7150/jca.44580
[Abstract] [Full text] [PDF]

ZNF521 which is downregulated by miR-802 suppresses malignant progression of Hepatocellular Carcinoma through regulating Runx2 expression
Nan Yang, Liang Wang, Tianxiang Chen, Runkun Liu, Zhikui Liu, Lei Zhang
J. Cancer 2020; 11(19): 5831-5839. doi:10.7150/jca.45190
[Abstract] [Full text] [PDF]

miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells
Zhexuan Li, Longbo Zhang, Zhiqiang Liu, Tianxiang Huang, Ying Wang, Yujie Ma, Xingqi Fang, Yanqing He, Yangying Zhou, Lei Huo, Jun Wu
J. Cancer 2020; 11(19): 5840-5851. doi:10.7150/jca.47588
[Abstract] [Full text] [PDF]

Value of Sarcopenia defined by the new EWGSOP2 consensus for the prediction of Postoperative Complications and Long-term Survival after Radical Gastrectomy for Gastric Cancer: A comparison with four common nutritional screening tools
Dong-Dong Huang, Hui-Yang Cai, Xi-Yi Chen, Wen-Xi Dong, Drugyel Wangchuk, Jing-Yi Yan, Xiao-Lei Chen, Qian-Tong Dong
J. Cancer 2020; 11(19): 5852-5860. doi:10.7150/jca.49815
[Abstract] [Full text] [PDF]