ISSN: 1837-9664Journal of Cancer
Global reach, higher impact
J Cancer 2023; 14(5):843-849. doi:10.7150/jca.81594 This issue Cite
Research Paper
Decompression Surgery Options for Metastatic Cervical Spine Lesions
1. Kuban State Medical University, Krasnodar, Russian Federation
2. Kemerovo State Medical University, Kemerovo, Russian Federation
Abstract
Background: Metastatic spinal lesions occur in 70% of patients with incurable cancer, and the most common site for bone metastases is the spine. Over the last decade, medical science has made significant progress in treating tumor damage to the spine. The study examined the efficacy of decompression surgery for patients with metastatic cervical spine lesions contributing to spinal cord compression.
Methods: The study enrolled 38 patients (27 females and 11 males, average age of 61.35±8.49 years) with metastatic cervical spine lesions resulting in cord compression relieved with surgery. Patients experienced improvement in pain and motor within one month of surgery addressing cervical metastatic disease.
Results: Complete or partial regression of pain syndrome 10 days after surgery was observed in 26 (68.4%) patients, one month later - in 33 (86.8%) patients, one year later - in 35 (92.1%) patients. Regression of neurological symptoms on the 10th day after surgery was observed in 8 (21.1%) patients, one month later - in 21 (55.3%) patients, one year later - in 34 (89.5%) patients. Two patients died between 3 and 12 months after surgery, having a worsening of their neurological status and pain syndrome.
Conclusions: Decompression surgeries for metastatic lesions of the cervical spine with spinal cord compression resulted in effective reduction of pain and neurological dysfunction.
Keywords: metastatic lesion of the spine, decompression surgery, vertebral stabilization, neurological disorders, regression of pain syndrome.
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