Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.

Sui, Qiaoqi; Lin, Junzhong; Peng, Jianhong; Zhao, Yujie; Deng, Yuxiang; Pan, Zhizhong

doi:10.7150/jca.21476

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J Cancer 2017; 8(19):3969-3974. doi:10.7150/jca.21476 This issue Cite

Research Paper

Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.

Qiaoqi Sui^*, Junzhong Lin^*, Jianhong Peng, Yujie Zhao, Yuxiang Deng, Zhizhong Pan^✉

Department of Colorectal Surgery, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine Guangzhou
*Qiaoqi Sui and Junzhong Lin contribute equally to this study

Citation:

Sui Q, Lin J, Peng J, Zhao Y, Deng Y, Pan Z. Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.. J Cancer 2017; 8(19):3969-3974. doi:10.7150/jca.21476. https://www.jcancer.org/v08p3969.htm

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Abstract

Purpose: To date, there is not enough evidence concerning the optimal treatment strategy for early rectal carcinoids, we conducted a meta-analysis in order to determine the feasible local treatment for these selected patients.

Methods: We searched the studies from the PubMed, Cochrane database, Medline, Ovid, SpringerLink, PMC and Embase between January 2007 and April 2017. Studies of local surgical excision compared with endoscopic resection for rectal carcinoids less than 20mm without adverse features were included. Data were analyzed by using Stata SE 12.0.

Results: Seven studies were included in this meta-analysis, with a total of 1056 patients. The data showed that local surgical excision was associated with higher complete resection rate than that of endoscopic resection (OR 5.837, 95%CI 2.048 to 16.632, P=0.001) but consuming longer procedural time (SMD 1.757, 95% CI 1.263 to 2.251, P=0.000). Additionally, incidences of recurrence and en bloc resection rate were comparable between two kinds of resections. The difference of post-operative complications remained unclear.

Conclusions: For rectal carcinoids sized 20mm or smaller without adverse features, endoscopic resection might be an efficient treatment, which achieved a comparable oncological safety as local surgical excision.

Keywords: rectal carcinoids sized 20mm or smaller without adverse features, local surgical excision, endoscopic resection, complete resection, recurrence

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APA

Sui, Q., Lin, J., Peng, J., Zhao, Y., Deng, Y., Pan, Z. (2017). Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.. Journal of Cancer, 8(19), 3969-3974. https://doi.org/10.7150/jca.21476.

ACS

Sui, Q.; Lin, J.; Peng, J.; Zhao, Y.; Deng, Y.; Pan, Z. Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.. J. Cancer 2017, 8 (19), 3969-3974. DOI: 10.7150/jca.21476.

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CSE

Sui Q, Lin J, Peng J, Zhao Y, Deng Y, Pan Z. 2017. Local surgical excision versus endoscopic resection for rectal carcinoid: A meta-analysis.. J Cancer. 8(19):3969-3974.

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