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J Cancer 2010; 1:32-37. doi:10.7150/jca.1.32 This volume Cite

Research Paper

Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?

Yan-gao Man✉

Gynecologic and Breast Research Laboratory, Armed Forces Institute of Pathology and American Registry of Pathology, Washington DC, USA, and Jilin University, China

✉ Corresponding author: Yan-gao Man, MD., PhD., Director of Gynecologic and Breast Research Laboratory, Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology and American Registry of Pathology. Tel: 202-782-1612; Fax: 202 More

Citation:
Man Yg. Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?. J Cancer 2010; 1:32-37. doi:10.7150/jca.1.32. https://www.jcancer.org/v01p0032.htm
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Abstract

Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically and immnohistochemically distinct subtypes with substantially different prognoses. Our recent studies have suggested that all breast cancer subtypes, however, may share a common pathway, tumor cell budding from focally disrupted tumor capsules, for their invasion. The potential mechanisms and clinical implications of our observations are discussed.

Keywords: Breast cancer heterogeneity, Breast cancer invasion, Cell budding, Basement membrane, Myoepithelial cell layer

Citation styles

APA
Man, Y.g. (2010). Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?. Journal of Cancer, 1, 32-37. https://doi.org/10.7150/jca.1.32.

ACS
Man, Y.g. Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?. J. Cancer 2010, 1, 32-37. DOI: 10.7150/jca.1.32.

NLM
Man Yg. Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?. J Cancer 2010; 1:32-37. doi:10.7150/jca.1.32. https://www.jcancer.org/v01p0032.htm

CSE
Man Yg. 2010. Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?. J Cancer. 1:32-37.

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