1. 3rd Department of Surgery, “AHEPA” University Hospital, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece 2. Anesthesiology Department, “AHEPA” University Hospital, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece 3. Department of Pharmacology and Department of Surgery, Faculty of Dentistry, University of Medicine and Pharmacy of Craiova, Craiova, Romania 4. Clinical Pharmacology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece 5. Surgery Department, University of Timisoara, Romania 6. General Surgery Department, "Dr Carol Davila", University of Medicine and Pharmacy, Bucuresti, Romania 7. University of Medicine and Pharmacy, Craiova, Romania
✉ Corresponding author: Paul Zarogoulidis, M.D, Ph.D, 3rd Department of Surgery, ``AHEPA`` University Hospital, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece. Mobile: 00306977271974; E-mail: pzarogcom
Citation:
Sapalidis K, Kosmidis C, Funtanidou V, Katsaounis A, Barmpas A, Koimtzis G, Mantalobas S, Alexandrou V, Aidoni Z, Koulouris C, Pavlidis E, Giannakidis D, Surlin V, Pantea S, Strambu V, Constantina RO, Amaniti A, Zarogoulidis P, Mogoantă S, Kesisoglou I, Sardeli C. Update on current pancreatic treatments: from molecular pathways to treatment. J Cancer 2019; 10(21):5162-5172. doi:10.7150/jca.36300. https://www.jcancer.org/v10p5162.htm
Pancreatic cancer is still diagnosed at a late stage although we have novel diagnostic tools. Pancreatic cancer chemotherapy treatment resistance is observed and therefore novel treatments are in need. Anti-cancer stem cell therapy, combination of chemotherapy and/or radiotherapy with immunotherapy, proteins/enzymes and gene therapy are currently under evaluation. Targeted treatment with tyrosine kinase inhibitors is also administered and novel inhibitors are also under evaluation. In the current review we present recent data from our search within the year 2018.
Keywords: pancreatic cancer, gene therapy, stem cells, cancer
Citation styles
APA
Sapalidis, K., Kosmidis, C., Funtanidou, V., Katsaounis, A., Barmpas, A., Koimtzis, G., Mantalobas, S., Alexandrou, V., Aidoni, Z., Koulouris, C., Pavlidis, E., Giannakidis, D., Surlin, V., Pantea, S., Strambu, V., Constantina, R.O., Amaniti, A., Zarogoulidis, P., Mogoantă, S., Kesisoglou, I., Sardeli, C. (2019). Update on current pancreatic treatments: from molecular pathways to treatment. Journal of Cancer, 10(21), 5162-5172. https://doi.org/10.7150/jca.36300.
ACS
Sapalidis, K.; Kosmidis, C.; Funtanidou, V.; Katsaounis, A.; Barmpas, A.; Koimtzis, G.; Mantalobas, S.; Alexandrou, V.; Aidoni, Z.; Koulouris, C.; Pavlidis, E.; Giannakidis, D.; Surlin, V.; Pantea, S.; Strambu, V.; Constantina, R.O.; Amaniti, A.; Zarogoulidis, P.; Mogoantă, S.; Kesisoglou, I.; Sardeli, C. Update on current pancreatic treatments: from molecular pathways to treatment. J. Cancer 2019, 10 (21), 5162-5172. DOI: 10.7150/jca.36300.
NLM
Sapalidis K, Kosmidis C, Funtanidou V, Katsaounis A, Barmpas A, Koimtzis G, Mantalobas S, Alexandrou V, Aidoni Z, Koulouris C, Pavlidis E, Giannakidis D, Surlin V, Pantea S, Strambu V, Constantina RO, Amaniti A, Zarogoulidis P, Mogoantă S, Kesisoglou I, Sardeli C. Update on current pancreatic treatments: from molecular pathways to treatment. J Cancer 2019; 10(21):5162-5172. doi:10.7150/jca.36300. https://www.jcancer.org/v10p5162.htm
CSE
Sapalidis K, Kosmidis C, Funtanidou V, Katsaounis A, Barmpas A, Koimtzis G, Mantalobas S, Alexandrou V, Aidoni Z, Koulouris C, Pavlidis E, Giannakidis D, Surlin V, Pantea S, Strambu V, Constantina RO, Amaniti A, Zarogoulidis P, Mogoantă S, Kesisoglou I, Sardeli C. 2019. Update on current pancreatic treatments: from molecular pathways to treatment. J Cancer. 10(21):5162-5172.
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