J Cancer 2018; 9(17):3058-3066. doi:10.7150/jca.26060

Research Paper

Risk Assessment and Hydrodissection Technique for Radiofrequency Ablation of Thyroid Benign Nodules

Tang Xiaoyin#, Li Ping#, Cui Dan, Ding Min, Chi Jiachang, Wang Tao, Shi Yaoping, Wang Zhi, Zhai Bo

Department of Tumor Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University,160# Pujian Road, Shanghai, 200127, China
# These authors contributed equally to this study

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Xiaoyin T, Ping L, Dan C, Min D, Jiachang C, Tao W, Yaoping S, Zhi W, Bo Z. Risk Assessment and Hydrodissection Technique for Radiofrequency Ablation of Thyroid Benign Nodules. J Cancer 2018; 9(17):3058-3066. doi:10.7150/jca.26060. Available from http://www.jcancer.org/v09p3058.htm

File import instruction


Purpose: This retrospective study aimed to explore the importance of risk assessment and hydrodissection pre-treatment for radiofrequency ablation of thyroid nodules and initially establish the concept of thyroid nodule risk assessment and the corresponding ablation norms.

Method: Based on the specific location of thyroid nodules, risk assessment and the corresponding preventive measures for thyroid ablation were established. During the period of 2015.10-2017.5, a total of 382 patients were enrolled to compare the safety and efficacy of the ablation for patients with or without risk assessment and the corresponding preventive measures. Statistical analysis encompassed Independent T test for continuous variables and Fisher's exact test/Chi-square test for categorical variables.

Result: Of all 382 patients, 188 patients underwent ablation with risk assessment and the corresponding preventive measures before ablation and 194 without, respectively. The patient characteristics, risk grading, ablation time, thyroid function after ablation and the complete ablation rate showed no statistical differences exsisted between two groups (P>0.05). The complication in very high risk nodules was avoided in the group of patients with risk assessment and preventive measures before ablation.

Conclusion: It is a very safe and effective way to carry out radiofrequency ablation after pre-treatment of thyroid nodules by hydrodissection technique according to risk assessment. It will provide clinicians with greater help in the ablation treatment of thyroid nodules, and improve the safety of the thyroid ablation.

Keywords: Thyroid Nodule, Neoplasm Grading, Ablation Techniques, Evaluation Studies, Comparative Study.