Global reach, higher impact
J Cancer 2011; 2:347-349. doi:10.7150/jca.2.347
Short Report
Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC)
Department of Hematology, Istituto Scientifico San Raffaele, Milano, Italy
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Citation:
Bregni M, Ciceri F, Peccatori J. Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC). J Cancer 2011; 2:347-349. doi:10.7150/jca.2.347. Available from http://www.jcancer.org/v02p0347.htm
Bregni M, Ciceri F, Peccatori J. Allogeneic Stem Cell Transplantation for Metastatic Renal Cell Cancer (RCC). J Cancer 2011; 2:347-349. doi:10.7150/jca.2.347. Available from http://www.jcancer.org/v02p0347.htm
Abstract
A variety of therapeutic options are now available for advanced renal cell cancer, including antiangiogenic and anti-mTOR agents. Allogeneic hematopoietic stem cell transplantation, through its graft-versus-tumor effect, can induce clinical responses and prolonged survival in selected cytokine-refractory patients. However, the still relevant transplant-related mortality due to toxicity and graft-versus-host disease is an obstacle to its widespread use.
Keywords: Allogeneic hematopoietic stem cell transplantation, advanced renal cell cancer, graft-versus-tumor.