Online advance articles

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A snapshot of the PD-1/PD-L1 pathway
Chinmoy Ghosh, Gary Luong, and Yue Sun
J. Cancer 2021; doi:10.7150/jca.57334; accepted
[Author manuscript]

Identification of a Prognostic Signature Model with Tumor Microenvironment for Predicting Disease-free Survival after Radical Prostatectomy
Hao Zhao, Xuening Zhang, Zhan Shi, Bingxin Guo, Wenli Zhang, Kun He, Xueqi Hu, Songhe Shi
J. Cancer 2021; doi:10.7150/jca.51173; accepted
[Author manuscript]

CDK1 serves as a novel therapeutic target for endometrioid endometrial cancer
Xue Ying, Xuan Che, Jianzhang Wang, Gen Zou, Qin Yu, Xinmei Zhang
J. Cancer 2021; doi:10.7150/jca.51139; accepted
[Author manuscript]

Exosomal miR-10b-5p mediates cell communication of gastric cancer cells and fibroblasts and facilitates cell proliferation
Ting Yan, Xiaping Wang, Guohua Wei, Hai Li, Leiyu Hao, Yan Liu, Xinqian Yu, Wei Zhu, Ping Liu, Yichao Zhu, Xin Zhou
J. Cancer 2021; doi:10.7150/jca.47817; accepted
[Author manuscript]

Multidisciplinary Team Consultation for Resectable Gastric Cancer: A Propensity Score Matching Analysis
Yonghe Chen, Jun Xiang, Dan Liu, Jian Xiao, Fei Xiong, Kaikai Wei, Aihong Liu, Shi Chen, Yaxi Zhu, Xiaochun Meng, Junsheng Peng
J. Cancer 2021; doi:10.7150/jca.53365; in press
[Author manuscript]

GPRC5A: An Emerging Prognostic Biomarker for Predicting Malignancy of Pancreatic Cancer Based on Bioinformatics Analysis
Xuetian Qian, Chengfei Jiang, Shanshan Shen, Xiaoping Zou
J. Cancer 2021; doi:10.7150/jca.52578; in press
[Author manuscript]

Co-expression of PD-L1 and HIF-1α predicts poor prognosis in Patients with Non-small Cell Lung Cancer after surgery
Hongmei Zheng, Yue Ning, Yuting Zhan, Sile Liu, Yang yang, Qiuyuan Wen, Songqing Fan
J. Cancer 2021; doi:10.7150/jca.53119; in press
[Author manuscript]

Corpora Cavernos Invasion vs. Corpus Spongiosum Invasion in penile Cancer: A Systematic Review and Meta-analysis
Zaishang Li, Xueying Li, Wayne Lam, Yabing Cao, Jiunhung Geng, Antonio Augusto Ornellas, Fangjian Zhou and Hui Han
J. Cancer 2021; doi:10.7150/jca.56504; in press
[Author manuscript]

Mutational landscape of PI3K-AKT-mTOR pathway in breast cancer:Implications for targeted therapeutics
Weikai Xiao; Guochun Zhang; Bo Chen; Xiaoqing Chen; Lingzhu Wen; Jianguo Lai; Xuerui Li; Min Li; Hao Liu; Jing Liu; Han Han-Zhang; Analyn Lizaso; Ning Liao
J. Cancer 2021; doi:10.7150/jca.52993; accepted
[Author manuscript]

Intratumoral Treatment with Chemotherapy and Immunotherapy for NSCLC with EBUS-TBNA 19G
Paul Zarogoulidis, Wolfgang Hohenforst-Schmidt, Haidong Huang, Chong Bai, Chrysanthi Sardeli, Kosmas Tsakiridis, Bojan Zaric , Tomi Kovacevic, Vladimir Stojsic, Tatjana Sarcev, Daliborka Bursac, Biljana Kukic, Sofia Baka, Evagelia Athanasiou, Dimitrios Hatzibougias, Electra Michalopoulou-Manoloutsiou, Savvas Petanidis, Dimitris Drougas, Konstantinos Drevelegas, Dimitris Paliouras, Nikolaos Mparmpetakis, Lutz Freitag
J. Cancer 2021; doi:10.7150/jca.55322; accepted
[Author manuscript]

MicroRNA Profiling of Morphologically Heterogeneous Clear Cell Renal Cell Carcinoma
Alessio Giubellino, Christopher J. Ricketts, Vanessa Moreno, W. Marston Linehan, Maria J. Merino
J. Cancer 2021; doi:10.7150/jca.52310; accepted
[Author manuscript]

The clinical value of indocyanine green fluorescence navigation system for laparoscopic partial nephrectomy in the case of complex renal clear cell carcinoma (R.E.N.A.L score ≥7)
Rongjiang Wang, Jianer Tang, Yu Chen, Zhihai Fang, Junwen Shen
J. Cancer 2021; doi:10.7150/jca.55033; in press
[Author manuscript]

Para-aortic lymph node metastasis in Lower Thoracic Esophageal Squamous Cell Carcinoma After Radical Esophagectomy: a CT-based atlas and its clinical implications for adjuvant radiotherapy
Luxi Ye, Lijun Zhou, Shengping Wang, Lining Sun, Jiazhou Wang, Quan Liu, Xi Yang, Li Chu, Xiaofei Zhang, Weigang Hu, Jie Lin, Zhengfei Zhu
J. Cancer 2021; doi:10.7150/jca.51212; in press
[Author manuscript]

Prognostic Value Of The Glasgow Prognostic Score On Overall Survival In Patients With Advanced Non-Small Cell Lung Cancer
Pan Mingmei, Zhao Yun, He Jianbo, Wu Huanqiong, Pan yujia, Yu Qitao, Zhou Shaozhang
J. Cancer 2021; doi:10.7150/jca.52215; accepted
[Author manuscript]

MMP9 and IGFBP1 Regulate Tumor Immune and Drive Tumor Progression in Clear Cell Renal Cell Carcinoma
Tianbo Xu, Su Gao, Jingchong Liu, Yu Huang, Ke Chen, Xiaoping Zhang
J. Cancer 2021; doi:10.7150/jca.48664; accepted
[Author manuscript]

Role of CT texture features for predicting outcome of pancreatic cancer patients with liver metastases
Haifeng Shi; Kequn Xu; Ruohan Yin; Yueting Shao; Muhan Liu; Junjie Hang, Xiaoyong Wang, Lixia Wu
J. Cancer 2021; doi:10.7150/jca.49569; accepted
[Author manuscript]

Cyr61 Mediates Oxaliplatin Resistance in Colorectal Cancer Cells by Regulating Bcl-XL Expression
Yanfang Song, Yanli Kang, Zhen Lin, Menglu Zeng, Pengchong Shi, Jia Lin, Pingxia Lu, Li Luo, Yingping Cao, Xianjin Zhu
J. Cancer 2021; doi:10.7150/jca.48891; in press
[Author manuscript]

Msi1 inhibits cervical cancer cell apoptosis by downregulating BAK through AKT signaling
Xian Liu, Yanru Zhang, PengSheng Zheng and Nan Cui
J. Cancer 2021; doi:10.7150/jca.52950; accepted
[Author manuscript]

Brucine Inhibits Proliferation of Glioblastoma Cells by Targeting the G-quadruplexes in the c-Myb Promoter
Qiaochu Liu, Qunhui Wang, Chuanqi Lv, Ziqiang Liu, Haijun Gao, Yong Chen, Gang Zhao
J. Cancer 2021; doi:10.7150/jca.53689; in press
[Author manuscript]

Prognostic efficacy of the combination of the pretreatment systemic immune-inflammation index and Epstein-Barr virus DNA status in locally advanced nasopharyngeal carcinoma patients
Ying Xiong, Liang-Liang Shi, Li-Sheng Zhu, Qian Ding, Li Ba, Gang Peng
J. Cancer 2021; doi:10.7150/jca.52539; accepted
[Author manuscript]

Can a Novel American Joint Committee on Cancer Prognostic Groups Stage for Help to Predict Survival of Patients with Surgery of Invasive Upper Tract Urothelial Carcinoma?
Zaishang Li, Xueying Li, Ying Liu, Jiequn Fang and Kefeng Xiao
J. Cancer 2021; doi:10.7150/jca.50417; in press
[Author manuscript]

Is cardia cancer a special type of gastric cancer? A differential analysis of early cardia cancer and non-cardia cancer
Xiao Liang
J. Cancer 2021; doi:10.7150/jca.51433; accepted
[Author manuscript]

MicroRNA-32-5p inhibits epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting SMAD family 3
JIN-XING ZHANG, WEI YANG, JUN-ZHENG WU, CHUN ZHOU, SHENG LIU, HAI-BIN SHI and WEI-ZHONG ZHOU
J. Cancer 2021; doi:10.7150/jca.48387; accepted
[Author manuscript]

JP3 enhances the toxicity of cisplatin on drug-resistant gastric cancer cells while reducing the damage to normal cells
Yi Zhang, Junjie Chen, Zhen Che, Chuanjun Shu, Dongyin Chen, Kun Ding, Aiping Li, Jianwei Zhou
J. Cancer 2021; doi:10.7150/jca.50306; in press
[Author manuscript]

Screening and bioinformatical analysis of differentially expressed genes in nasopharyngeal carcinoma
Weiqian Guo, Xiaomin Zheng, Lei Hua, Xianbin Zheng, Yangyang Zhang, Bin Sun, Zhenchao Tao, Jin Gao
J. Cancer 2021; doi:10.7150/jca.48979; in press
[Author manuscript]

Aberrant KIF23 Expression Is Associated with Adverse Clinical Outcome and Promotes Cellular Malignant Behavior through the Wnt/β-catenin Signaling Pathway in Colorectal Cancer
Zhiyu Ji, Aoning Mi, Mengmeng Li, Quanying Li, Changjiang Qin
J. Cancer 2021; doi:10.7150/jca.51565; in press
[Author manuscript]

Prognostic significance of FSCN family in multiple myeloma
Cong Deng, Tingting Qian, Xu Ye , Qiang Zhou, Tiansheng Zeng, Wenhui Huang, Pei Zhu,Qingfu Zhong,Zhihua Wu,Huoyan Zhu,Qing Lin,Wenjuan Zhang,Lin Fu,Yongjiang Zheng, Chaozeng Si
J. Cancer 2021; doi:10.7150/jca.53675; in press
[Author manuscript]

Study on the correlation between helicobacter pylori and biological characteristics of early
Guanqun Chao Shuo Zhang
J. Cancer 2021; doi:10.7150/jca.46392; in press
[Author manuscript]

CAR-T Cells For Colorectal Cancer: Target-selection And Strategies For Improved Activity and Safety
Huali Li, Chao Yang, Huangrong Cheng, Shuoyang Huang, Yongbin Zheng
J. Cancer 2021; doi:10.7150/jca.50509; in press
[Author manuscript]

Ethyl Acetate Subfractions from Ethanol Extracts of Fermented Oats (Avena sativa L.) Exert Anti-cancer Properties in Vitro and in Vivo through G2/M and S Phase Arrest and Apoptosis
Nanhai Zhang, Liang Zhao, Shengbao Cai, Xiang Zeng, Wei Wu, Baoping Ji, Feng Zhou
J. Cancer 2021; doi:10.7150/jca.48993; in press
[Author manuscript]

Clinical significance of site-specific metastases in pancreatic cancer: a study based on both clinical trial and real-world data
Lixia Wu, Lina Zhu, Kequn Xu, Siyuan Zhou, Yang Zhou, Tiening Zhang, Junjie Hang, Benny Chung-Ying Zee
J. Cancer 2021; doi:10.7150/jca.50317; in press
[Author manuscript]

Peri-tumoral brain edema associated with glioblastoma correlates with tumor recurrence
Xingping Qin, Rui Liu, Farhana Akter, Lingxia Qin, Qiurong Xie, Yanfei Li, Zhihong Jian, Haowen Qiao, Wen Zhao, Renzhong Liu, Songlin Wu
J. Cancer 2021; doi:10.7150/jca.53198; in press
[Author manuscript]

ARRB1 Drives Gallbladder Cancer Progression by Facilitating TAK1/MAPK Signaling Activation
Xudong Zhang, Zhijun Kong , Xiaoliang Xu , Xiao Yun, Jiadeng Chao, Dong Ding , Tao Li , Yuan Gao, Naifu Guan, Chunfu Zhu, Xihu Qin
J. Cancer 2021; doi:10.7150/jca.53325; in press
[Author manuscript]

Identification of hub genes-based predictive model in hepatocellular carcinoma by robust rank aggregation and regression analysis
Di Wu, Yun Pan, Xueyong Zheng
J. Cancer 2021; doi:10.7150/jca.52089; in press
[Author manuscript]

Radiofrequency ablation vs. stereotactic body radiotherapy for stage IA non-small cell lung cancer in nonsurgical patients
Shuanshuan Xie, Ming Li, Yingyi Qin, Changhui Wang, Lihong Fan
J. Cancer 2021; doi:10.7150/jca.51413; accepted
[Author manuscript]

Identification of prognostic and diagnostic biomarkers with weighted gene co-expression network analysis as potential joint therapy target BRAFi in PTC
YaLi Han, XiaQing Yu, YuZhen Yin, Zhongwei Lv, ChengYou Jia, Yina Liao, Hongyan Sun, Tie Liu, Lele Cong, ZhaoLiang Fei, Da Fu, Xianling CongShen Qu
J. Cancer 2021; doi:10.7150/jca.51551; in press
[Author manuscript]

Preliminary study on SPECT/CT imaging of pancreatic cancer xenografts by targeting integrin α5 in pancreatic stellate cells
Tao Wang, Ye Peng, Rou Li, Xiao Li, Changjing Zuo
J. Cancer 2021; doi:10.7150/jca.51190; in press
[Author manuscript]

Clinical Importance of ADC in the Prediction of 125I in the Treatment for Gliomas
Congxiao Wang, Zhijian Xu, Song Wang, Lijing Peng, Wei Zhang, Xueda Li, Lili Yang, Ying Luan, Tao Su, Zixiang Li, Xiaokun Hu
J. Cancer 2021; doi:10.7150/jca.50789; in press
[Author manuscript]

Comparison Of Proteomics Profiles Between Xenografts Derived From Cell Lines And Primary Tumors Of Thyroid Carcinoma
Luo Fang, Yu-jia Liu, Yi-wen Zhang, Zong-fu Pan, Li-ke Zhong, Lie-hao Jiang, Jia-feng Wang, Yang-yang Qian, Ling-ya Chen, Ping Huang, Ming-hua Ge, Zhuo Tan
J. Cancer 2021; doi:10.7150/jca.50897; in press
[Author manuscript]

LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-145 inhibition
Hai-yan Piao, Shuai Guo, Haoyi Jin, Yue Wang, Jun Zhang
J. Cancer 2021; doi:10.7150/jca.49138; accepted
[Author manuscript]

Reduced miR-16 levels are associated with VEGF upregulation in high-risk myelodysplastic syndromes
Bei Xiong, Yanbo Nie, Yalan Yu, Shixuan Wang, Xuelan Zuo
J. Cancer 2021; doi:10.7150/jca.52455; in press
[Author manuscript]

Proteomic profiling reveals a signature for optimizing prognostic prediction in colon cancer
Shan Zezhi, Luo Dakui, Liu Qi, Cai Sanjun, Wang Renjie, Ma Yanlei, Li Xinxiang
J. Cancer 2021; doi:10.7150/jca.50630; accepted
[Author manuscript]

Preoperative Portal Vein Embolization for Liver Resection: An Updated Meta-Analysis and Systematic Review
Yu Huang, Wenhao Ge, Yang Kong, Yuan Ding, Bingqiang Gao, Xiaohui Qian, Weilin Wang
J. Cancer 2021; doi:10.7150/jca.50371; in press
[Author manuscript]

Title: Transcription factor E2F4 is an indicator of poor prognosis and is related with to immune infiltration of in hepatocellular carcinoma
Qiuxian Zheng, Qiang Fu, Jia Xu, Xinyu Gu, Haibo Zhou, Chen Zhi
J. Cancer 2021; doi:10.7150/jca.51616; in press
[Author manuscript]

Androgen Plays a Carcinogenic Role in EOC via the PI3K/AKT Signaling Pathway in an AR-Dependent Manner
Yanfang Li, Sha Li, Yizhou Zhang, Shuhong Shi, Shan Qin, Chang Wang, Jingle Ma, Huan Chen, Huixian Cui
J. Cancer 2021; doi:10.7150/jca.51099; in press
[Author manuscript]

LINC00665 Promotes Ovarian Cancer Progression through Regulating the miRNA-34a-5p/E2F3 Axis
Dan Xu, Qingxia Song, Ying Liu, Wansu Chen, Lijuan LU, Min Xu, Xiaohui Fang, Wenjie Zhao, Huifang Zhou
J. Cancer 2021; doi:10.7150/jca.51457; in press
[Author manuscript]

Segmentectomy or wedge Wedge resection Resection in Stage IA Lung Squamous Cell Carcinoma and Adenocarcinoma?
Guoshu Li, Shuanshuan Xie, Feng Hu ,Min Tan, Lihong Fan, Changhui Wang
J. Cancer 2021; doi:10.7150/jca.49683; in press
[Author manuscript]

AURKA and FAM83A are Prognostic Biomarkers and Correlated with Tumor-infiltrating Lymphocytes in Smoking Related Lung Adenocarcinoma
Mengyu Zhang, Chen Huo, Yingxiao Jiang, Jianyu Liu, Yican Yang, Yunhong Yin and Yiqing Qu
J. Cancer 2021; doi:10.7150/jca.51321; in press
[Author manuscript]

The Effects of Lentivirus-Mediated Gene Silencing of RARβ on the Stemness Capability of Non-Small Cell Lung Cancer
Noor Hanis Abu Halim, Norashikin Zakaria, Kumitaa Theva Das, Moon Nian Lim, Kamal Shaik Fakiruddin, Badrul Hisham Yahaya
J. Cancer 2021; doi:10.7150/jca.50793; accepted
[Author manuscript]

R-split-EPOCH plus high dose methotrexate in untreated diffuse large B cell lymphoma with MYC rearrangement or double expression of MYC and BCL-2
Peng Sun, Yu Wang, Cui Chen, Hang Yang, Man Nie, Xiao-Qing Sun, Xiao-Hua He, Wen-Qi Jiang, Zhi-Ming Li
J. Cancer 2021; doi:10.7150/jca.52958; in press
[Author manuscript]

HPV58 E7 Protein Expression Profile in Cervical Cancer and CIN with Immunohistochemistry
Qiaoli Zheng, Xianzhen chen, Rui Han, Jiang Zhu, Hui Wang, Lingjing Chen, Yinjing Song, Luxia Chen, Hao Cheng, Na Jin
J. Cancer 2021; doi:10.7150/jca.50816; in press
[Author manuscript]

Sequential administration of anti-PD-1 and anti-Tim-3 combined with an SA-GM-CSF-anchored vaccine overcomes adaptive immune resistance to reject established cancer
Xinji Zhang, Guang Liu, Xianghua Shi, Xiaojun Shi, Jinlong Li, Lijun Mo, Jimin Gao, Zhaolin Long, Wanlong Tan
J. Cancer 2021; doi:10.7150/jca.44769; in press
[Author manuscript]

Overexpression of HIPK2 removes the transrepression of proapoptotic genes mediated by the CtBP1-p300-FOXO3a complex and increases the chemosensitivity in osteosarcoma
Ning Duan, Wentao Zhang, Zhong Li, Liang Sun, Tao Song, Zirui Yu, Xun Chen, Wei Ma
J. Cancer 2021; doi:10.7150/jca.52115; in press
[Author manuscript]

SLC25A21 suppresses cell growth in bladder cancer via the reactive oxygen species-mediated mitochondrion-dependent apoptosis pathway
Yong Wang, Jiawen Gao, Shasha Hu, Weiting Zeng, Hui Chen, Liankun Sun, Shuang Wang
J. Cancer 2021; doi:10.7150/jca.50906; accepted
[Author manuscript]

Syntaxin 2 promotes colorectal cancer proliferation by increasing the secretion of exosomes
YongXia Wang, Yongzhen Li, Hong Zhou, XinLai Qian, Huhan Hu
J. Cancer 2021; doi:10.7150/jca.51494; in press
[Author manuscript]

UXT antisense RNA 1 sever as a novel prognostic long non-coding RNA in early stage pancreatic ductal adenocarcinoma patients after receiving pancreaticoduodenectomy
Xiwen Liao, Rui Huang, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Xin Zhou, Chuangye Han, Hao Su, Xinping Ye, Kang Liu, Guangzhi Zhu, Tao Peng
J. Cancer 2021; doi:10.7150/jca.46084; accepted
[Author manuscript]

Androgen receptor (AR) Decreases HCC Cells Migration and Invasion via miR-325/ACP5 Signaling
Xiwu Ouyang, Lemeng Feng, Guodong Liu, Lei Yao, Zhiming Wang, Shiqing Liu, Yao Xiao, Gewen Zhang
J. Cancer 2021; doi:10.7150/jca.49200; in press
[Author manuscript]

Classification Of Clear Cell Renal Cell Carcinoma Based On Tumor Suppressor Genomic Profiling
Weimin Zhong, Fengling Zhang, Chaoqun Huang, Yao Lin, Jiyi Huang
J. Cancer 2021; doi:10.7150/jca.50462; accepted
[Author manuscript]

Comprehensive investigation of the clinical significance of long non-coding RNA HOXA-AS2 in acute myeloid leukemia using genome-wide RNA sequencing dataset
Rui Huang, Xiwen Liao, Xiangkun Wang, Qiaochuan Li
J. Cancer 2021; doi:10.7150/jca.48045; accepted
[Author manuscript]

EVALUATION OF ANTI-CANCER FUNCTION OF TRANSGENIC HEMATOPOIETIC NATURAL KILLER CELLS
Alireza Pirahmadiana, Shaharudin Abdul Razak, Shamsul Azlin B Ahmad Shamsuddin
J. Cancer 2021; doi:10.7150/jca.48343; accepted
[Author manuscript]

Demethylzelasteral Contributes to Epithelial-Mesenchymal Transition (EMT) in ESCC through the Wnt/β-catenin Signaling Pathway
Jiarui Yu, Wei Wang, Baolin Liu, Jinling Gu, Meiyue Liu, Siyuan Chen, Guogui Sun
J. Cancer 2021; doi:10.7150/jca.45493; accepted
[Author manuscript]

Multimodality MRI-based Prediction Model for Histologic Grade of Hepatocellular Carcinoma
Baolin Wu, Fei Jia, Xuekun Li, Kaiyu Wang, Dongming Han, Zhiyun Jia
J. Cancer 2021; doi:10.7150/jca.49029; accepted
[Author manuscript]

The association between sites of distant metastases and overall survival in cervical cancer
Ce Wang, Zhenyi Xu, Jiali Song, Yuhong Lu, Meng Wang, Yan Hou
J. Cancer 2021; doi:10.7150/jca.41046; accepted
[Author manuscript]


Note: This page contains manuscripts that have been accepted by this journal. They haven't been copyedited by the journal and the content may change before final publication.