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Volume 15 (14); 2024

Research Papers

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Exosomal miRNA-146a-5p Derived from Senescent Hepatocellular Carcinoma Cells Promotes Aging and Inhibits Aerobic Glycolysis in Liver Cells via Targeting IRF7 Sijia Yang, Ang Li, Lihong Lv, Zhihua Zheng, Peiqing Liu, Jun Min, Jinxing Wei J. Cancer 2024; 15(14): 4448-4466. doi:10.7150/jca.96500 Full text PDF PubMed PMC


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Genomic Alterations Correlated to Trastuzumab Resistance and Clinical Outcomes in HER2+/HR- Breast Cancers of Patients Living in Northwestern China Gang Ma, Binliang Huo, Yanwei Shen, Xulong Zhu, Chong Cheng, Wensheng Li, Wei Cao, Jianhui Li J. Cancer 2024; 15(14): 4467-4476. doi:10.7150/jca.84832 Full text PDF PubMed PMC


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Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway Aixin Yu, Yiqi Wang, Jun Qin, Junrong Lei, Wendai Bao, Zhiqiang Dong J. Cancer 2024; 15(14): 4477-4489. doi:10.7150/jca.97357 Full text PDF PubMed PMC


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MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells Chunlin Tao, Xiaoge Ni J. Cancer 2024; 15(14): 4490-4502. doi:10.7150/jca.96185 Full text PDF PubMed PMC


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Impact of Pulmonary microbiota on lung cancer treatment-related pneumonia Maoyuan Zhao, Wang Hou, Dan Pu, Zhixi Li, Li Tu, Calista Jia Ling Ow, Jie Tian, Weimin Li J. Cancer 2024; 15(14): 4503-4512. doi:10.7150/jca.93818 Full text PDF PubMed PMC


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Identification of Hypoxia and Mitochondrial-related Gene Signature and Prediction of Prognostic Model in Lung Adenocarcinoma Wenhao Zhao, Hua Huang, Zexia Zhao, Chen Ding, Chaoyi Jia, Yingjie Wang, Guannan Wang, Yongwen Li, Hongyu Liu, Jun Chen J. Cancer 2024; 15(14): 4513-4526. doi:10.7150/jca.97374 Full text PDF PubMed PMC


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Administering immunotherapy after anti-vascular targeted therapy improves overall survival of patients with metastatic clear cell renal cell carcinoma Zhiwei Hou, Long Lai, HuaGuo Wu, Benkui Zou, Ni Xu, Dongyuan Zhu, Xiaokun Wang, Hui Zhang J. Cancer 2024; 15(14): 4527-4533. doi:10.7150/jca.96514 Full text PDF PubMed PMC


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Synergistic Anti-Tumor Efficacy Achieved by Reversing Drug Resistance through the Regulation of the Tumor Immune Microenvironment with IL-12 and Osimertinib Combination Therapy Huiqin Ding, Lijuan Wu, Huan Qin, Wenhui Fu, Yajun Wang, Mingyuan Wu, Jiangang Wang, Yantao Han J. Cancer 2024; 15(14): 4534-4550. doi:10.7150/jca.95407 Full text PDF PubMed PMC


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Relationship between sex differences in drinking, smoking, and exercising and the incidence of malignancies and medical procedures: a cross-sectional study of 21,916 participants in China Mingyan Hao, Yifan Li, Wenjun Ma, Lizheng Wang, Janzhong Zheng, Yibo Wu J. Cancer 2024; 15(14): 4551-4565. doi:10.7150/jca.95456 Full text PDF PubMed PMC


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OTUB1 Promotes Glioblastoma Growth by Inhibiting the JAK2/STAT1 Signaling Pathway Jun Yang, Na Zhang, Zesong He, Junyi Xiong, Wei Meng, Chengcheng Xue, Li Ying, Meihua Li, Mei Liu, Taohui Ouyang J. Cancer 2024; 15(14): 4566-4576. doi:10.7150/jca.96360 Full text PDF PubMed PMC


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EGR1 Promotes Erastin-induced Ferroptosis Through Activating Nrf2-HMOX1 Signaling Pathway in Breast Cancer Cells Zhirong Lin, Zifei Liu, Zhilong Pan, Yunyi Zhang, Xinyu Yang, Yaxin Feng, Ruihua Zhang, Wenfeng Zeng, Chang Gong, Jianing Chen J. Cancer 2024; 15(14): 4577-4590. doi:10.7150/jca.95328 Full text PDF PubMed PMC


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Causal associations of BAFF-R on IgD+ CD24- B cell immune cell trait with hepatocellular carcinoma and the mediating role of phenylacetylglutamate levels: a Mendelian randomization study Xuan Zhu, Zongchao Qiu, Maochun Yang, Jiali Yang, Lingxi Kong, Limin Li, Yingting Huang, Li Xie J. Cancer 2024; 15(14): 4591-4603. doi:10.7150/jca.96059 Full text PDF PubMed PMC


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Genetic polymorphism of IL-18 influences susceptibility to lung cancer in population of eastern China Xu Chen, Yanping Yao, Jianle Lao, Hua Li, Hailong Fu, Jun Qiu J. Cancer 2024; 15(14): 4604-4611. doi:10.7150/jca.97039 Full text PDF PubMed PMC


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Establishing and Validating a novel Prognostic Model in the Initial Diagnosis of Non-small Cell Lung Cancer with Bone Metastases Bin Li, Deying Su, Xiaoyan Wen, Miaomiao Jia, Ning Xue, Shulin Chen, Chaoju Lou J. Cancer 2024; 15(14): 4612-4622. doi:10.7150/jca.95784 Full text PDF PubMed PMC


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Apolipoprotein L3 inhibits breast cancer proliferation and modulates cell cycle via the P53 pathway Hao Yu, Siyan Li, Xing Li, Yanbiao Liu, Zhaobu Wang, Mengyao Cui, Feng Jin, Xinmiao Yu J. Cancer 2024; 15(14): 4623-4635. doi:10.7150/jca.96903 Full text PDF PubMed PMC


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Efficacy of Whole-Brain Radiotherapy Plus Simultaneous Integrated Boost (SIB-WBRT) for Lung Cancer Brain Metastases Qian Bi, Jing Shen, Pengyu Li, Yuhao Zeng, Xin Lian, Fuquan Zhang J. Cancer 2024; 15(14): 4636-4642. doi:10.7150/jca.95804 Full text PDF PubMed PMC


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Coumestrol facilitates apoptosis in colorectal cancer cells by interacting with ZIP8 protein via the ferroptosis pathway Jing Geng, Yingying Wang, Fengchun Lv, Xiaomin Yu, Mingyu Gong, Jie Zhang, Zicheng Zhao, Xiaoyue Zhu, Xiaoyu Zhang, Jian Yang, Xiu-An Yang J. Cancer 2024; 15(14): 4656-4667. doi:10.7150/jca.94628 Full text PDF PubMed PMC


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DPF2 overexpression correlates with immune infiltration and dismal prognosis in hepatocellular carcinoma Kejian Yang, Jusen Nong, Haixiang Xie, Zuyin Wan, Xin Zhou, Junqi Liu, Chongjiu Qin, Jianzhu Luo, Guangzhi Zhu, Tao Peng J. Cancer 2024; 15(14): 4668-4685. doi:10.7150/jca.97437 Full text PDF PubMed PMC


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Integrated pan-cancer genomic analysis reveals the role of SLC30A5 in the proliferation, metastasis, and prognosis of hepatocellular carcinoma Yihan Liu, Tong Lu, Runze Li, Long Cui, Rui Xu, Shenyi Teng, Denis Baranenko, Tianze Zhang, Lida Yang, Rui Qie, Dan Xiao J. Cancer 2024; 15(14): 4686-4699. doi:10.7150/jca.97214 Full text PDF PubMed PMC


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A Novel Cellular Senescence-related lncRNA Signature for Predicting the Prognosis of Breast Cancer Patients Fangxu Yin, Wenhao Zhao, Chen Ding, Chong Hou, Song Wang, Chao Sun, Zexia Zhao, Zhanrui Zhang, Fan Ren, Yuying Liu, Xuanguang Li J. Cancer 2024; 15(14): 4700-4716. doi:10.7150/jca.96107 Full text PDF PubMed PMC


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Development of Polymeric Micelles for Combined Delivery of Luteolin and Doxorubicin for Cancer Therapy Saad Alshamrani, Ashok Kumar, Mohammed S. Aldughaim, Khalid M. Alghamdi, Muhammad Delwar Hussain, Fars K. Alanazi, Mohsin Kazi J. Cancer 2024; 15(14): 4717-4730. doi:10.7150/jca.96402 Full text PDF PubMed PMC


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A Novel Signature Based on Angiogenesis-Related Genes Predicts the Prognosis and Immunotherapy Response in HER2-Positive Breast Cancer Shuanglong Chen, Weiheng Cui, Jiale Dong, Wenyan Chen, Hongmei Dong, Ruijun Zhao J. Cancer 2024; 15(14): 4731-4748. doi:10.7150/jca.94120 Full text PDF PubMed PMC


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Exploring the Prognostic Value and Immune Infiltration Patterns of GPRC5A Across Multiple Cancer Types Song Hu, Yan Chen, Beibei Sun J. Cancer 2024; 15(14): 4749-4758. doi:10.7150/jca.93217 Full text PDF PubMed PMC


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TLE4 downregulation identified by WGCNA and machine learning algorithm promotes papillary thyroid carcinoma progression via activating JAK/STAT pathway Junyu Lin, Beichen Cai, Qian Lin, Xinjian Lin, Biao Wang, Xiangjin Chen J. Cancer 2024; 15(14): 4759-4776. doi:10.7150/jca.95501 Full text PDF PubMed PMC

Review

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Nanotechnology as a new strategy for the diagnosis and treatment of gliomas Jun Lei, Yiyang Huang, Yichuan Zhao, Zhi Zhou, Lei Mao, Yanhui Liu J. Cancer 2024; 15(14): 4643-4655. doi:10.7150/jca.96859 Full text PDF PubMed PMC

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