J Cancer 2023; 14(5):835-842. doi:10.7150/jca.80803 This issue Cite

Review

Current status and progress of the development of prostate cancer vaccines

Jie Wang1#, Kaichen Zhou1#, Huihuang Zhu2#, Fukun Wei1, Sai Ma1, Yi Kan1, Bingheng Li1, Lijun Mao1,2✉

1. Department of Urology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
2. Jiangsu Key Laboratory of Biological Cancer Therapy, Xuzhou Medical University, Xuzhou 221002, China.
# Contributed equally

Citation:
Wang J, Zhou K, Zhu H, Wei F, Ma S, Kan Y, Li B, Mao L. Current status and progress of the development of prostate cancer vaccines. J Cancer 2023; 14(5):835-842. doi:10.7150/jca.80803. https://www.jcancer.org/v14p0835.htm
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Abstract

Graphic abstract

At present, common treatments of prostate cancer mainly include surgery, radiotherapy, chemotherapy and hormone therapy. However, patients have high recurrence rate after treatment, and are prone to castration-resistant prostate cancer. Tumor vaccine is based on tumor specific antigen (TSA) and tumor associated antigen (TAA) to activate specific immune response of the body to cancer cells. With continuous maturity of tumor vaccine technology, different forms of prostate cancer vaccines have been developed, such as cellular vaccines, extracellular-based anti-tumor vaccines, polypeptide vaccines, and nucleic acid vaccines. In this review, we summarize current status and progress in the development of prostate cancer vaccines.

Keywords: prostate cancer, cancer vaccine, tumor specific antigen, tumor associated antigen


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APA
Wang, J., Zhou, K., Zhu, H., Wei, F., Ma, S., Kan, Y., Li, B., Mao, L. (2023). Current status and progress of the development of prostate cancer vaccines. Journal of Cancer, 14(5), 835-842. https://doi.org/10.7150/jca.80803.

ACS
Wang, J.; Zhou, K.; Zhu, H.; Wei, F.; Ma, S.; Kan, Y.; Li, B.; Mao, L. Current status and progress of the development of prostate cancer vaccines. J. Cancer 2023, 14 (5), 835-842. DOI: 10.7150/jca.80803.

NLM
Wang J, Zhou K, Zhu H, Wei F, Ma S, Kan Y, Li B, Mao L. Current status and progress of the development of prostate cancer vaccines. J Cancer 2023; 14(5):835-842. doi:10.7150/jca.80803. https://www.jcancer.org/v14p0835.htm

CSE
Wang J, Zhou K, Zhu H, Wei F, Ma S, Kan Y, Li B, Mao L. 2023. Current status and progress of the development of prostate cancer vaccines. J Cancer. 14(5):835-842.

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