J Cancer
2020; 11(23):6970-6981.
doi:10.7150/jca.44384 This issueCite
Review
The functional roles of long noncoding RNA DANCR in Human Cancers
Lei Pan1, Xiudi Xiao1, Yuan Zhao1, Liang Yin1, Min Fu2,3, Xu Zhang2✉, Pengcheng Jiang3✉
1. Department of Breast Surgery, The Affiliated People's Hospital of Jiangsu University, 8 Dianli Road, Zhenjiang, Jiangsu 212002, China. 2. Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China. 3. Department of General Surgery, The Affiliated People's Hospital of Jiangsu University, 8 Dianli Road, Zhenjiang, Jiangsu 212002, China.
✉ Corresponding authors: Xu Zhang, Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, Jiangsu University. 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China. E-mail: xuzhangedu.cn; Pengcheng Jiang, Department of General Surgery, The Affiliated People's Hospital of Jiangsu University. 8 Dianli Road, Zhenjiang, Jiangsu 212002, China. E-mail: pc_jiangcom.More
Citation:
Pan L, Xiao X, Zhao Y, Yin L, Fu M, Zhang X, Jiang P. The functional roles of long noncoding RNA DANCR in Human Cancers. J Cancer 2020; 11(23):6970-6981. doi:10.7150/jca.44384. https://www.jcancer.org/v11p6970.htm
Long noncoding RNAs (lncRNAs) have been wildly explored in various cellular processes and their aberrant expression could lead to tumorigenesis, development and progression. Differentiation antagonizing non-protein coding RNA (DANCR), a well-known lncRNA that is aberrant expression in various tumors, including hepatocellular carcinoma, gastric cancer, colorectal cancer, breast cancer, lung cancer and glioma and so on, in which it functions as oncogene mainly, contributing to cancer development and progression. High expressed DANCR is correlated with poor prognosis. In the present review, we summarize recent progression concerning the role, potential clinical utilities and underlying molecular mechanisms of DANCR related to occurrence and development of multiple cancers.
Keywords: long noncoding RNA, DANCR, biomarker, therapeutic target
Citation styles
APA
Pan, L., Xiao, X., Zhao, Y., Yin, L., Fu, M., Zhang, X., Jiang, P. (2020). The functional roles of long noncoding RNA DANCR in Human Cancers. Journal of Cancer, 11(23), 6970-6981. https://doi.org/10.7150/jca.44384.
ACS
Pan, L.; Xiao, X.; Zhao, Y.; Yin, L.; Fu, M.; Zhang, X.; Jiang, P. The functional roles of long noncoding RNA DANCR in Human Cancers. J. Cancer 2020, 11 (23), 6970-6981. DOI: 10.7150/jca.44384.
NLM
Pan L, Xiao X, Zhao Y, Yin L, Fu M, Zhang X, Jiang P. The functional roles of long noncoding RNA DANCR in Human Cancers. J Cancer 2020; 11(23):6970-6981. doi:10.7150/jca.44384. https://www.jcancer.org/v11p6970.htm
CSE
Pan L, Xiao X, Zhao Y, Yin L, Fu M, Zhang X, Jiang P. 2020. The functional roles of long noncoding RNA DANCR in Human Cancers. J Cancer. 11(23):6970-6981.
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