J Cancer 2011; 2:331-332. doi:10.7150/jca.2.331 This volume Cite

Short Report

Chimeric Antigen Receptor Therapy for B-cell Malignancies

David L Porter1,2✉, Michael Kalos1,3, Zhaohui Zheng1,3, Bruce Levine1,3, Carl June1,3

1. Abramson Cancer Center, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, USA
2. Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, USA
3. Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, USA

Citation:
Porter DL, Kalos M, Zheng Z, Levine B, June C. Chimeric Antigen Receptor Therapy for B-cell Malignancies. J Cancer 2011; 2:331-332. doi:10.7150/jca.2.331. https://www.jcancer.org/v02p0331.htm
Other styles

File import instruction

Abstract

We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.

Keywords: B-cell Malignancies, CART-19, Chimeric Antigen Receptor Therapy


Citation styles

APA
Porter, D.L., Kalos, M., Zheng, Z., Levine, B., June, C. (2011). Chimeric Antigen Receptor Therapy for B-cell Malignancies. Journal of Cancer, 2, 331-332. https://doi.org/10.7150/jca.2.331.

ACS
Porter, D.L.; Kalos, M.; Zheng, Z.; Levine, B.; June, C. Chimeric Antigen Receptor Therapy for B-cell Malignancies. J. Cancer 2011, 2, 331-332. DOI: 10.7150/jca.2.331.

NLM
Porter DL, Kalos M, Zheng Z, Levine B, June C. Chimeric Antigen Receptor Therapy for B-cell Malignancies. J Cancer 2011; 2:331-332. doi:10.7150/jca.2.331. https://www.jcancer.org/v02p0331.htm

CSE
Porter DL, Kalos M, Zheng Z, Levine B, June C. 2011. Chimeric Antigen Receptor Therapy for B-cell Malignancies. J Cancer. 2:331-332.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) License. See http://ivyspring.com/terms for full terms and conditions.
Popup Image