Impact Factor ISSN: 1837-9664
Review Tumor Treating Fields in Solid Tumors: A Multiscale Evidence Framework with Gastric Cancer as an Early Translational Case Study Full text PDF
Research Paper Systemic Immune Traits and Candidate Genes in Uveal Melanoma: An Exploratory Mendelian Randomization and Transcriptomic Study Full text PDF
Research Paper Dynamic Postoperative Skeletal Muscle Trajectories Predict Survival in Stage II-III Gastric Cancer Full text PDF
Research Paper RFC1, RPA1, and POLE expression characterizes the clinical behavior and immune microenvironment of colorectal cancer Full text PDF
Review Who Should Undergo Surgery, and at What Operative Risk? Two Conditions Governing Cytoreduction in TKI-Treated Gastrointestinal Stromal Tumor Full text PDF
Research Paper Integrative Locus-Resolved Genomics Uncovers Distinct Genetic Links Between Leukocyte Telomere Length and Colon Cancer Susceptibility Full text PDF
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Gastrointestinal stromal tumor is where targeted therapy was first shown to work, and where the surgical question remains least resolved. Two randomized trials of cytoreductive surgery closed on accrual for a structural reason: both required randomization at best radiological response, the moment at which individual equipoise collapses. The literature that filled the gap is uniformly selected and is commonly set aside on that ground. Setting it aside ...
Background: Uveal melanoma (UM) is classified by recurrent genomic alterations and by high-risk, immune-rich tumor states, but the contribution of inherited variation in peripheral immune phenotypes remains unclear. We aimed to identify peripheral immune traits and candidate genes associated with UM and characterize candidate-gene expression in its immune microenvironment. We combined two-sample Mendelian randomization (MR) of 731 immunophenotypes, ...