Impact Factor ISSN: 1837-9664
Research Paper Bevacizumab or Aflibercept in Combination with Second-Line FOLFIRI after Progression on FOLFOX Plus Bevacizumab in Metastatic Colorectal Cancer: A Comparative Study Full text PDF
Review Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer Full text PDF
Research Paper Associations of HMGA2 single-nucleotide polymorphisms with clinicopathological features of tongue squamous cell carcinoma in Taiwanese men with distinct lifestyle-related risk factors Full text PDF
Research Paper Separability of histopathology foundation model embeddings of stimulated Raman histology images for lung carcinoma subtyping Full text PDF
Review Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges Full text PDF PubMed PMC
Review Regulatory roles of E3 ubiquitin ligase RNF128 in inflammatory diseases and tumors Full text PDF PubMed PMC
Issue 9; 2026
Indexed in PubMed and SCI expanded; full texts in Europe PMC. ...
Background: Oral squamous cell carcinoma (OSCC) is a predominant malignancy of the oral cavity, with tongue squamous cell carcinoma (TSCC) accounting for a substantial proportion of cases worldwide. High-mobility group A protein 2 (HMGA2) is a nonhistone chromatin-binding factor implicated in aggressive malignant phenotypes of various human cancers. However, the effects of HMGA2 variants on OSCC susceptibility and tumor clinicopathological aggressiveness ...
Chimeric Antigen Receptor T cells (CAR-T) therapy represents a groundbreaking technology in the field of tumor immunotherapy. This innovative approach involves the genetic engineering of T cells to specifically identify and eradicate tumor cells, and it has been shown to yield remarkable efficacy in treating hematological malignancies. This article provides a comprehensive overview of the core advancements in CAR-T technology, emphasizing the evolution ...