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Review tsRNA's Biological Function and its Potential Application in Disease Diagnosis and Prognosis Full text PDF
Research Paper Long-Term Empagliflozin Treatment (50 Days) Attenuates Protease Activity, Migration, and Stemness-Associated Phenotypes in BFTC-909 Renal Pelvis Transitional Cell Carcinoma Cells Full text PDF
Research Paper A digital polymerase chain reaction method targeting non-recombined T-cell receptor sequences aids in diagnosing primary cutaneous T-cell lymphomas Full text PDF
Research Paper Single-cell Transcriptomics Uncovers the Tumor Microenvironment and Collagen-CD44 Axis in HIV Positive Cervical Squamous Cell Carcinoma Full text PDF
Research Paper Integrative bulk and single-cell transcriptomic analysis identifies an ac4C-related signature in lung adenocarcinoma Full text PDF
Research Paper Cell-Specific DNA Methylation Markers in Plasma cfDNA Reveal Diagnostic Potential for Head and Neck Cancer Full text PDF
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Introduction: Human immunodeficiency virus (HIV) infection markedly increases the incidence and worsens clinical outcomes of cervical squamous cell carcinoma (CSCC). The single-cell landscape of the tumor microenvironment (TME) in HIV positive CSCC (HIV-CSCC) remains poorly defined, and its cellular and molecular differences from HIV negative CSCC are largely unclear. Methods: We performed single-cell RNA sequencing (scRNA-seq) on tumor tissues from ...
Purpose: Head and neck cancer ranks as the seventh most common type of cancer worldwide. For patients diagnosed at advanced stages, the five-year survival rate remains below 40%, underscoring the urgent need for early detection strategies. However, current diagnostic approaches face considerable limitations. Furthermore, tissue biopsy remains invasive and impractical for routine screening. In light of these challenges, this study aims to identify ...