J Cancer
2020; 11(21):6226-6233.
doi:10.7150/jca.46613 This issueCite
Review
miR-552: an important post-transcriptional regulator that affects human cancer
Yuhao Zou, Xin Zhao✉, Yin Li, Shiwei Duan✉
Medical Genetics Center, Ningbo University School of Medicine, Ningbo, Zhejiang, China.
✉ Corresponding authors: Shiwei Duan (E-mail: duanshiweiedu.cn) and Dr. Xin Zhao (E-mail: zhaoxinedu.cn).
Citation:
Zou Y, Zhao X, Li Y, Duan S. miR-552: an important post-transcriptional regulator that affects human cancer. J Cancer 2020; 11(21):6226-6233. doi:10.7150/jca.46613. https://www.jcancer.org/v11p6226.htm
MiR-552 is a small non-coding RNA located on chromosome 1p34.3, and its expression level is significantly up-regulated in tissues or cells of various tumors. miR-552 can target multiple genes. These targeted genes play important regulatory roles in biological processes such as gene transcription and translation, cell cycle progression, cell proliferation, apoptosis, cell migration, and invasion. Besides, miR-552 may affect the efficacy of various anticancer drugs by targeting genes such as TP53 and RUNX3. This review summarizes the biological functions and clinical expressions of miR-552 in human cancer. Our goal is to explore the potential value of miR-552 in the diagnosis, prognosis, and treatment of human cancer.
Keywords: miR-552, cancer, diagnosis, prognosis, drug resistance
Citation styles
APA
Zou, Y., Zhao, X., Li, Y., Duan, S. (2020). miR-552: an important post-transcriptional regulator that affects human cancer. Journal of Cancer, 11(21), 6226-6233. https://doi.org/10.7150/jca.46613.
ACS
Zou, Y.; Zhao, X.; Li, Y.; Duan, S. miR-552: an important post-transcriptional regulator that affects human cancer. J. Cancer 2020, 11 (21), 6226-6233. DOI: 10.7150/jca.46613.
NLM
Zou Y, Zhao X, Li Y, Duan S. miR-552: an important post-transcriptional regulator that affects human cancer. J Cancer 2020; 11(21):6226-6233. doi:10.7150/jca.46613. https://www.jcancer.org/v11p6226.htm
CSE
Zou Y, Zhao X, Li Y, Duan S. 2020. miR-552: an important post-transcriptional regulator that affects human cancer. J Cancer. 11(21):6226-6233.
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