J Cancer 2018; 9(16):2946-2952. doi:10.7150/jca.25539

Research Paper

The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm)

Wenwu Ling1*, Manni Wang2*, Xuelei Ma2, Tingting Qiu1, Jiawu Li1, Qiang Lu1✉, Yan Luo1✉

1. Department of Ultrasound, West China Hospital of Sichuan University, Chengdu 610041, China
2. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital of Sichuan University, Chengdu 610041, China
*: these authors contributed equally to this work.

Abstract

To evaluate the diagnostic accuracy of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) for patients at risk for hepatocellular carcinoma with hepatic nodules (≤2cm). We retrospectively evaluated 56 CEUS exam records of hepatic nodules (≤2cm) performed between January 2015 and July 2016 at West China hospital. Each nodule was classified into a LI-RADS-CEUS category by two radiologists according to imaging features. The ultimate CEUS categories were then compared with pathological reports and their correlation was then calculated. Inter-observer agreement for LI-RADS between reader A and B was κ, 0.690, illustrating good consistency. The diagnostic accuracy of LR-5 on hepatocellular carcinoma (HCC) was 86.49% but 11.11% for LR-M. LI-RADS-CEUS is a potential standardized categorization system for high-risk HCC patients but might also increase the false-negative diagnosis of nodules of less than 2cm.

Keywords: Contrast-enhanced ultrasound, Liver imaging reporting and data system, and Small hepatic nodules

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How to cite this article:
Ling W, Wang M, Ma X, Qiu T, Li J, Lu Q, Luo Y. The preliminary application of liver imaging reporting and data system (LI-RADS) with contrast-enhanced ultrasound (CEUS) on small hepatic nodules (≤ 2cm). J Cancer 2018; 9(16):2946-2952. doi:10.7150/jca.25539. Available from http://www.jcancer.org/v09p2946.htm