J Cancer 2015; 6(7):610-615. doi:10.7150/jca.11710

Research Paper

Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative

Nisreen Elsayegh1, Jessica Profato1, Angelica M. Gutierrez Barrera2, Heather Lin3, Henry M. Kuerer4, Can Ardic2, Jennifer K. Litton2, Debasish Tripathy2, Banu K. Arun1,2 ✉

1. Clinical Cancer Genetics, the University of Texas MD Anderson Cancer Center, Houston, TX
2. Department of Breast Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX
3. Department of Biostatistics, the University of Texas MD Anderson Cancer Center, Houston, TX
4. Department of Surgical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX

Abstract

The authors retrospectively examined the contralateral prophylactic mastectomy (CPM) rate among 100 women with ductal carcinoma in situ who are BRCA negative. Of 100 women with ductal carcinoma in situ, 31 elected contralateral prophylactic mastectomy (CPM). Factors associated with increased likelihood of undergoing contralateral prophylactic mastectomy (CPM) among this cohort were: family history of ovarian cancer, marital status, reconstruction, mastectomy of the affected breast, and tamoxifen use.

Keywords: contralateral prophylactic mastectomy, BRCA negative

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How to cite this article:
Elsayegh N, Profato J, Barrera AMG, Lin H, Kuerer HM, Ardic C, Litton JK, Tripathy D, Arun BK. Predictors that Influence Election of Contralateral Prophylactic Mastectomy among Women with Ductal Carcinoma in Situ who are BRCA-Negative. J Cancer 2015; 6(7):610-615. doi:10.7150/jca.11710. Available from http://www.jcancer.org/v06p0610.htm