J Cancer 2013; 4(9):724-726. doi:10.7150/jca.5921

Short Research Communication

A Comparative Study of the effects of Vitamins C and E in the Development of Sarcoma 180 in Mice

Gerson S. Paiva1✉, Carlton A. Taft1, Marcos C. Carvalho1, Ivone A. de Souza2, Elisângela C. Barbosa da Silva2, Karen P. Cavalcanti2, Ronaldo F. L. Jr.3, Neil M. De la Cruz4

1. Centro Brasileiro de pesquisas Físicas, Rua Dr.Xavier Sigaud, 150, 22290-180, Rio de Janeiro, Rio de Janeiro, Brazil
2. Centro de Ciências Biológicas, Departamento de Antibióticos, Universidade Federal de Pernambuco, 1235, 50670-901, Recife, Pernambuco, Brazil
3. Departamento de Química, Universidade Católica de Pernambuco, Rua do Principe, 526, 50050-900, Recife, Pernambuco, Brazil
4. Departamento de Física, Pontifícia Universidade Católica do Rio de Janeiro Rua Marquês de São Vicente, 225, 22450-900, Rio de Janeiro, Rio de Janeiro, Brazil

Abstract

In this work we have investigated the effects of vitamins C and E on tumors via the mice xenotransplant model of sarcoma 180 (S180) in vivo. The experimental results suggest that dosages of 100 mg/kg vitamin C and 400 mg/kg vitamin E yields a great inhibitory behavior on tumors.

Keywords: Vitamin C, Vitamin E, Sarcoma 180, mice

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How to cite this article:
Paiva GS, Taft CA, Carvalho MC, de Souza IA, da Silva ECB, Cavalcanti KP, L. Jr. RF, De la Cruz NM. A Comparative Study of the effects of Vitamins C and E in the Development of Sarcoma 180 in Mice. J Cancer 2013; 4(9):724-726. doi:10.7150/jca.5921. Available from http://www.jcancer.org/v04p0724.htm